Publications by authors named "Christopher Sarsons"

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Apabetalone, a Clinical-Stage, Selective BET Inhibitor, Opposes DUX4 Target Gene Expression in Primary Human FSHD Muscle Cells.
Christopher D Sarsons, Dean Gilham, Laura M Tsujikawa, Sylwia Wasiak, Li Fu

Biomedicines· September 2023

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Apabetalone Downregulates Fibrotic, Inflammatory and Calcific Processes in Renal Mesangial Cells and Patients with Renal Impairment.
Dean Gilham, Sylwia Wasiak, Brooke D Rakai, Li Fu, Laura M Tsujikawa, Christopher D Sarsons

Biomedicines· June 2023

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Dual mechanism: Epigenetic inhibitor apabetalone reduces SARS-CoV-2 Delta and Omicron variant spike binding and attenuates SARS-CoV-2 RNA induced inflammation.
Li Fu, Dean Gilham, Stephanie C Stotz, Christopher D Sarsons, Brooke D Rakai

Int Immunopharmacol· April 2023

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Breaking boundaries: Pan BETi disrupt 3D chromatin structure, BD2-selective BETi are strictly epigenetic transcriptional regulators.
Laura M Tsujikawa, Olesya A Kharenko, Stephanie C Stotz, Brooke D Rakai, Christopher D Sarsons

Biomed Pharmacother· August 2022

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Apabetalone (RVX-208) reduces vascular inflammation in vitro and in CVD patients by a BET-dependent epigenetic mechanism.
Laura M Tsujikawa, Li Fu, Shovon Das, Christopher Halliday, Brooke D Rakai, Christopher D Sarsons

Clin Epigenetics· July 2019

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Apabetalone downregulates factors and pathways associated with vascular calcification.
Dean Gilham, Laura M Tsujikawa, Christopher D Sarsons, Christopher Halliday, Sylwia Wasiak

Atherosclerosis· January 2019

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Understanding and improving assays for cytotoxicity of nanoparticles: what really matters?
Hagar I Labouta, Christopher Sarsons, Jacob Kennard, M Juliana Gomez-Garcia, Kenrick Villar

RSC Adv· June 2018

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Surface-grafted polyethylene glycol conformation impacts the transport of PEG-functionalized liposomes through a tumour extracellular matrix model.
Hagar I Labouta, M Juliana Gomez-Garcia, Christopher D Sarsons, Trinh Nguyen, Jacob Kennard

RSC Adv· February 2018

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Quantum dot interactions and flow effects in angiogenic zebrafish (Danio rerio) vessels and human endothelial cells.
Xiao-Yu Jiang, Christopher D Sarsons, M Juliana Gomez-Garcia, David T Cramb, Kristina D Rinker

Nanomedicine· April 2017

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Tailoring nanoparticle designs to target cancer based on tumor pathophysiology.
Edward A Sykes, Qin Dai, Christopher D Sarsons, Juan Chen, Jonathan V Rocheleau

Proc Natl Acad Sci U S A· March 2016

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Testing nanoparticles for angiogenesis-related disease: charting the fastest route to the clinic.
Christopher D Sarsons, Amy Tekrony, Kristin Yaehne, Sarah Childs, Kristina D Rinker

J Biomed Nanotechnol· September 2014

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