Publications by authors named "Christopher Sassetti"

Claim this Profile
C
Cross-species blood transcriptional correlates of BCG-mediated protection against tuberculosis include innate and adaptive immune processes.
Kate Bridges, Denis Awany, Anele Gela, Temwa-Dango Mwambene, Sherry L Kurtz, Christopher M Sassetti

JCI Insight· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Reference-based chemical-genetic interaction profiling to elucidate small molecule mechanism of action in Mycobacterium tuberculosis.
Austin N Bond, Marek Orzechowski, Shuting Zhang, Ishay Ben-Zion, Allison Lemmer, Christopher M Sassetti

Nat Commun· November 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Noncanonical T cell responses are associated with protection from tuberculosis in mice and humans.
Megan K Proulx, Christine D Wiggins, Charlotte J Reames, Claire Wu, Michael C Kiritsy, Christopher M Sassetti

J Exp Med· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Mycobacterium tuberculosis Transposon Sequencing Database (MtbTnDB): A Large-Scale Guide to Genetic Conditional Essentiality.
Adrian Jinich, Anisha Zaveri, Michael A DeJesus, Amanda Spencer, Ricardo Almada-Monter, Christopher M Sassetti

Mol Microbiol· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restriction.
Patricia S Grace, Joshua M Peters, Jaimie Sixsmith, Richard Lu, Edward B Irvine, Christopher M Sassetti

Immunity· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
BCG induced innate immune response heterogeneity and susceptibility to pediatric tuberculosis.
Christine Anterasian, Anele Gela, Temwa-Dango Mwambene, Javeed A Shah, Josh Ivie, Christopher M Sassetti

J Immunol· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cross-species blood transcriptional correlates of BCG-mediated protection against tuberculosis include innate and adaptive immune processes.
Kate Bridges, Denis Awany, Anele Gela, Temwa-Dango Mwanbene, Christopher M Sassetti

bioRxiv· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Frequently arising ESX-1-associated phase variants influence fitness in the presence of host and antibiotic pressures.
Michael J Luna, Peter O Oluoch, Jiazheng Miao, Peter Culviner, Kadamba Papavinasasundaram, Christopher M Sassetti

mBio· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeted delivery of antitubercular drugs using glucan lipid particles.
Eleni Jaecklein, Kadamba Papavinasasundaram, Gary R Ostroff, Christopher Sassetti, Ernesto R Soto

Microbiol Spectr· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Chemical genetic interactions elucidate pathways controlling tuberculosis antibiotic efficacy during infection.
Peter O Oluoch, Eun-Ik Koh, Megan K Proulx, Charlotte J Reames, Kadamba G Papavinasasundaram, Christopher M Sassetti

Proc Natl Acad Sci U S A· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of .
Nelson V Simwela, Eleni Jaecklein, Christopher M Sassetti, David G Russell

Elife· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cross-species transcriptomics translation reveals a role for the unfolded protein response in Mycobacterium tuberculosis infection.
Krista M Pullen, Ryan Finethy, Seung-Hyun B Ko, Charlotte J Reames, Christopher M Sassetti

NPJ Syst Biol Appl· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of .
Nelson V Simwela, Eleni Jaecklein, Christopher M Sassetti, David G Russell

bioRxiv· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mycobacterium tuberculosis virulence lipid PDIM inhibits autophagy in mice.
Ekansh Mittal, G V R Krishna Prasad, Sandeep Upadhyay, Jully Sadadiwala, Andrew J Olive, Christopher M Sassetti

Nat Microbiol· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The updated mouse universal genotyping array bioinformatic pipeline improves genetic QC in laboratory mice.
Matthew W Blanchard, John Sebastian Sigmon, Jennifer Brennan, Chidima Ahulamibe, Michelle E Allen, Christopher M Sassetti

G3 (Bethesda)· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genome-wide screen of Mycobacterium tuberculosis-infected macrophages revealed GID/CTLH complex-mediated modulation of bacterial growth.
Nelson V Simwela, Luana Johnston, Paulina Pavinski Bitar, Eleni Jaecklein, Craig Altier, Christopher M Sassetti

Nat Commun· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Chemical genetic interactions elucidate pathways controlling tuberculosis antibiotic efficacy during infection.
Peter O Oluoch, Eun-Ik Koh, Megan K Proulx, Charlotte J Reames, Kadamba G Papavinasasundaram, Christopher M Sassetti

bioRxiv· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genome-wide screen of infected macrophages identified the GID/CTLH complex as a determinant of intracellular bacterial growth.
Nelson V Simwela, Luana Johnston, Paulina Pavinski Bitar, Eleni Jaecklein, Craig Altier, Christopher M Sassetti

bioRxiv· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The structure of Mycobacterium thermoresistibile MmpS5 reveals a conserved disulfide bond across mycobacteria.
Bonnie J Cuthbert, Jessica Mendoza, Rodger de Miranda, Kadamba Papavinasasundaram, Christopher M Sassetti

Metallomics· March 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Multiple genetic loci influence vaccine-induced protection against Mycobacterium tuberculosis in genetically diverse mice.
Sherry L Kurtz, Richard E Baker, Frederick J Boehm, Chelsea C Lehman, Lara R Mittereder, Christopher M Sassetti

PLoS Pathog· March 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Glycerol contributes to tuberculosis susceptibility in male mice with type 2 diabetes.
Nuria Martinez, Lorissa J Smulan, Michael L Jameson, Clare M Smith, Kelly Cavallo, Christopher M Sassetti

Nat Commun· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Differentiating the roles of Mycobacterium tuberculosis substrate binding proteins, FecB and FecB2, in iron uptake.
Rodger de Miranda, Bonnie J Cuthbert, Thaís Klevorn, Alex Chao, Jessica Mendoza, Christopher M Sassetti

PLoS Pathog· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Rip1 intramembrane protease contributes to iron and zinc homeostasis in .
Samantha J Nelson, John T Williams, John A Buglino, Subhalaxmi Nambi, Lisa J Lojek, Christopher M Sassetti

mSphere· August 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genome-wide screen identifies host loci that modulate Mycobacterium tuberculosis fitness in immunodivergent mice.
Rachel K Meade, Jarukit E Long, Adrian Jinich, Kyu Y Rhee, David G Ashbrook, Christopher M Sassetti

G3 (Bethesda)· August 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Phase variation as a major mechanism of adaptation in complex.
Roger Vargas, Michael J Luna, Luca Freschi, Maximillian Marin, Ruby Froom, Christopher M Sassetti

Proc Natl Acad Sci U S A· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis