Publications by authors named "Christopher Schafer"

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RIPK3 Protects Against Endothelial Activation and Vascular Permeability in a Mouse Model of Ischemia-Reperfusion Injury.
Charmain F Johnson, Christopher M Schafer, Kathryn Y Burge, Brian G Coon, Hala Chaaban

Arterioscler Thromb Vasc Biol· January 2026

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Constitutive activity of an atypical chemokine receptor revealed by inverse agonistic nanobodies.
Claudia V Perez Almeria, Omolade Otun, Roman Schlimgen, Thomas D Lamme, Lotte Di Niro, Christopher T Schafer

Nat Commun· December 2025

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Optimizing Medicare Annual Wellness Visits Through Quality Improvement: Leveraging Process, Continuity, and Combined Visits.
Courtney D Wellman, Richard Conway, Ashley Beaty, Kueitsung Shih, Christopher Schafer

Ann Fam Med· September 2025

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Targeting endothelial ERG to mitigate vascular regression in retinopathies.
Eric Ma, Christopher M Schafer, Jun Xie, Yelyzaveta Rudenko, John T H Knapp

Proc Natl Acad Sci U S A· September 2025

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Effect of phosphorylation barcodes on arrestin binding to a chemokine receptor.
Qiuyan Chen, Christopher T Schafer, Somnath Mukherjee, Kai Wang, Martin Gustavsson

Nature· July 2025

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Signal termination of the chemokine receptor CCR9 is governed by an arrestin-independent phosphorylation mechanism.
Thomas D Lamme, Martine J Smit, Christopher T Schafer

J Biol Chem· May 2025

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Distinct activation mechanisms of CXCR4 and ACKR3 revealed by single-molecule analysis of their conformational landscapes.
Christopher T Schafer, Raymond F Pauszek, Martin Gustavsson, Tracy M Handel, David P Millar

Elife· April 2025

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Distinct Activation Mechanisms of CXCR4 and ACKR3 Revealed by Single-Molecule Analysis of their Conformational Landscapes.
Christopher T Schafer, Raymond F Pauszek, Martin Gustavsson, Tracy M Handel, David P Millar

bioRxiv· February 2025

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Targeting endothelial ERG to mitigate vascular regression and neuronal ischemia in retinopathies.
Eric Ma, Christopher M Schafer, Jun Xie, Yelyzaveta Rudenko, John T H Knapp

bioRxiv· December 2024

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Comparative analysis of In vivo endothelial cell translatomes across central nervous system vascular beds.
Ana J Chucair-Elliott, Kevin Pham, Audrey C A Cleuren, Christopher M Schafer, Courtney T Griffin

Exp Eye Res· November 2024

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Constitutive activity of an atypical chemokine receptor revealed by inverse agonistic nanobodies.
Claudia V Perez Almeria, Omolade Otun, Roman Schlimgen, Thomas D Lamme, Caitrin Crudden, Christopher T Schafer

bioRxiv· November 2024

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Endothelial RIPK3 minimizes organotypic inflammation and vascular permeability in ischemia-reperfusion injury.
Charmain F Johnson, Christopher M Schafer, Kathryn Y Burge, Brian G Coon, Hala Chaaban

bioRxiv· November 2024

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Deficient RPE mitochondrial energetics leads to subretinal fibrosis in age-related neovascular macular degeneration.
Xiang Ma, Wenjing Wu, Miwa Hara, Junwen Zhou, Carolina Panzarin, Christopher M Schafer

Commun Biol· September 2024

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Atypical Chemokine Receptor 3 "Senses" CXC Chemokine Receptor 4 Activation Through GPCR Kinase Phosphorylation.
Christopher T Schafer, Qiuyan Chen, John J G Tesmer, Tracy M Handel

Mol Pharmacol· October 2023

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Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory Challenge.
Christopher M Schafer, Silvia Martin-Almedina, Katarzyna Kurylowicz, Neil Dufton, Lourdes Osuna-Almagro

Arterioscler Thromb Vasc Biol· August 2023

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ACKR3-arrestin2/3 complexes reveal molecular consequences of GRK-dependent barcoding.
Qiuyan Chen, Christopher T Schafer, Somnath Mukherjee, Martin Gustavsson, Parth Agrawal

bioRxiv· July 2023

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Atypical Chemokine Receptor 3 'Senses' CXC Chemokine Receptor 4 Activation Through GPCR Kinase Phosphorylation.
Christopher T Schafer, Qiuyan Chen, John J G Tesmer, Tracy M Handel

bioRxiv· March 2023

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Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory Challenge.
Christopher M Schafer, Silvia Martin-Almedina, Katarzyna Kurylowicz, Neil Dufton, Lourdes Osuna-Almagro

bioRxiv· February 2023

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Oxygen-dependent regulation of E3(SCF)ubiquitin ligases and a Skp1-associated JmjD6 homolog in development of the social amoeba Dictyostelium.
Andrew W Boland, Elisabet Gas-Pascual, Braxton L Nottingham, Hanke van der Wel, Nitin G Daniel, Christopher M Schafer

J Biol Chem· September 2022

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Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
Yu-Chen Yen, Christopher T Schafer, Martin Gustavsson, Stefanie A Eberle, Pawel K Dominik

Sci Adv· July 2022

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Effects of analgesic and surgical modality on immune response in colorectal cancer surgery.
Mohammed Faisal, Christopher Niels Schäfer, Pär Myrelid, Martin E Winberg, Johan D Söderholm

Surg Oncol· September 2021

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Novel fluorescent GPCR biosensor detects retinal equilibrium binding to opsin and active G protein and arrestin signaling conformations.
Christopher T Schafer, Anthony Shumate, David L Farrens

J Biol Chem· December 2020

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An inhibitor of endothelial ETS transcription factors promotes physiologic and therapeutic vessel regression.
Christopher M Schafer, Jami M Gurley, Katarzyna Kurylowicz, Prisca K Lin, Wen Chen

Proc Natl Acad Sci U S A· October 2020

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The chromatin-remodeling enzyme CHD3 plays a role in embryonic viability but is dispensable for early vascular development.
Jun Xie, Siqi Gao, Christopher Schafer, Sarah Colijn, Vijay Muthukumar

PLoS One· September 2020

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Proinflammatory Mediators, IL (Interleukin)-1β, TNF (Tumor Necrosis Factor) α, and Thrombin Directly Induce Capillary Tube Regression.
Gretchen M Koller, Christopher Schafer, Scott S Kemp, Kalia N Aguera, Prisca K Lin

Arterioscler Thromb Vasc Biol· February 2020

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