Publications by authors named "Christopher Seet"

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IL-9 as a naturally orthogonal cytokine with optimal JAK/STAT signaling for engineered T cell therapy.
Hua Jiang, Sam Limsuwannarot, Kayla R Kulhanek, Aastha Pal, Ossama Labiad, Christopher S Seet

Immunity· November 2025

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Author Correction: Barcoded HIV-1 reveals viral persistence driven by clonal proliferation and distinct epigenetic patterns.
Tian-Hao Zhang, Yuan Shi, Natalia L Komarova, Dominik Wodarz, Matthew Kostelny, Christopher Seet

Nat Commun· October 2025

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Stage-specific CAR-mediated signaling generates naïve-like, TCR-null CAR T cells from induced pluripotent stem cells.
Sang Pil Yoo, Xuegang Yuan, Claire Engstrom, Patrick Chang, Suwen Li, Christopher Seet

bioRxiv· April 2025

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Generation of allogeneic CAR-NKT cells from hematopoietic stem and progenitor cells using a clinically guided culture method.
Yan-Ruide Li, Yang Zhou, Jiaji Yu, Yu Jeong Kim, Miao Li, Christopher S Seet

Nat Biotechnol· March 2025

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Allogeneic CD33-directed CAR-NKT cells for the treatment of bone marrow-resident myeloid malignancies.
Yan-Ruide Li, Ying Fang, Siyue Niu, Yichen Zhu, Yuning Chen, Christopher S Seet

Nat Commun· February 2025

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Barcoded HIV-1 reveals viral persistence driven by clonal proliferation and distinct epigenetic patterns.
Tian-Hao Zhang, Yuan Shi, Natalia L Komarova, Dominik Wodarz, Matthew Kostelny, Christopher Seet

Nat Commun· February 2025

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IL-9 as a naturally orthogonal cytokine with optimal JAK/STAT signaling for engineered T cell therapy.
Hua Jiang, Sam Limsuwannarot, Kayla R Kulhanek, Aastha Pal, Lea W Rysavy, Christopher S Seet

bioRxiv· January 2025

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Pomalidomide/Daratumumab/Dexamethasone in Relapsed or Refractory Multiple Myeloma: Final Overall Survival From MM-014.
Nizar J Bahlis, Christy Samaras, Donna Reece, Michael Sebag, Jeffrey Matous, Christopher S Seet

Clin Lymphoma Myeloma Leuk· December 2024

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Assessing Patients beyond the Simple Optics of BMI: The Concomitant Role of Sarcopenia and BMI in Predicting Kidney Transplant Outcomes.
Christopher Seet, Laura Clementoni, Mohammed Rashid Akhtar, Pankaj Chandak, Mohammed Saoud

Life (Basel)· August 2024

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Generation of antigen-specific mature T cells from RAG1RAG2B2M stem cells by engineering their microenvironment.
Patrick C Chang, Xuegang Yuan, Alexandre Zampieri, Chloe Towns, Sang Pil Yoo, Christopher S Seet

Nat Biomed Eng· April 2024

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Distinct roles of hematopoietic cytokines in the regulation of leukemia stem cells in murine MLL-AF9 leukemia.
Yanchun Li, Christopher S Seet, Ryan Mack, Kanak Joshi, Austin P Runde

Stem Cell Reports· January 2024

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Predicting Atrial Fibrillation after Ischemic Stroke: Clinical, Genetics, and Electrocardiogram Modelling.
Mervyn Qi Wei Poh, Carol Huilian Tham, Jeremiah David Ming Siang Chee, Seyed Ehsan Saffari, Kenny Wee Kian Tan, Christopher Ying Hao Seet

Cerebrovasc Dis Extra· December 2023

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Revolutionizing the Management of Large-Core Ischaemic Strokes: Decoding the Success of Endovascular Therapy in the Recent Stroke Trials.
Gareth Zigui Lim, Jonathan Yexian Lai, Christopher Ying Hao Seet, Carol Huilian Tham, Narayanaswamy Venketasubramanian

J Cardiovasc Dev Dis· December 2023

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CCL21-DC in situ vaccination in murine NSCLC overcomes resistance to immunotherapy and generates systemic tumor-specific immunity.
Ramin Salehi-Rad, Raymond J Lim, Yushen Du, Linh M Tran, Rui Li, Christopher Seet

J Immunother Cancer· September 2023

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Transient SARS-CoV-2 RNA-Dependent RNA Polymerase Mutations after Remdesivir Treatment for Chronic COVID-19 in Two Transplant Recipients: Case Report and Intra-Host Viral Genomic Investigation.
Shangxin Yang, Ashrit Multani, Jacob M Garrigues, Michael S Oh, Peera Hemarajata, Christopher S Seet

Microorganisms· August 2023

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IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing.
Yang Pan, John W Phillips, Beatrice D Zhang, Miyako Noguchi, Eric Kutschera, Christopher S Seet

Proc Natl Acad Sci U S A· May 2023

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Strength of CAR signaling determines T cell versus ILC differentiation from pluripotent stem cells.
Suwen Li, Chloe S Wang, Amélie Montel-Hagen, Ho-Chung Chen, Shawn Lopez, Christopher S Seet

Cell Rep· March 2023

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Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing.
Grace E McAuley, Gloria Yiu, Patrick C Chang, Gregory A Newby, Beatriz Campo-Fernandez, Christopher S Seet

Cell· March 2023

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Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation.
Zhiyuan Mao, Pavlo A Nesterenko, Jami McLaughlin, Weixian Deng, Giselle Burton Sojo, Christopher S Seet

Proc Natl Acad Sci U S A· August 2022

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Pomalidomide, dexamethasone, and daratumumab immediately after lenalidomide-based treatment in patients with multiple myeloma: updated efficacy, safety, and health-related quality of life results from the phase 2 MM-014 trial.
Nizar J Bahlis, David S Siegel, Gary J Schiller, Christy Samaras, Michael Sebag, Christopher S Seet

Leuk Lymphoma· June 2022

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3D-organoid culture supports differentiation of human CAR iPSCs into highly functional CAR T cells.
Zhiqiang Wang, Helen P McWilliams-Koeppen, Hernan Reza, Julie R Ostberg, Wuyang Chen, Christopher S Seet

Cell Stem Cell· April 2022

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Generation of Artificial Thymic Organoids from Human and Murine Hematopoietic Stem and Progenitor Cells.
Amélie Montel-Hagen, Steven Tsai, Christopher S Seet, Gay M Crooks

Curr Protoc· April 2022

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3D-organoid culture supports differentiation of human CAR iPSCs into highly functional CAR T cells.
Zhiqiang Wang, Helen P McWilliams-Koeppen, Hernan Reza, Julie R Ostberg, Wuyang Chen, Christopher S Seet

Cell Stem Cell· April 2022

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Incidence of Cerebral Venous Thrombosis Following SARS-CoV-2 Infection vs mRNA SARS-CoV-2 Vaccination in Singapore.
Tian Ming Tu, Shen Jia Yi, Jasmine Shimin Koh, Seyed Ehsan Saffari, Rebecca Hui Min Hoe, Christopher Ying Hao Seet, Raymond Chee Seong Seet

JAMA Netw Open· March 2022

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Latency reversal plus natural killer cells diminish HIV reservoir in vivo.
Jocelyn T Kim, Tian-Hao Zhang, Camille Carmona, Bryanna Lee, Christopher S Seet

Nat Commun· January 2022

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