Publications by authors named "Christopher Weghorst"

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Impact of Cyanotoxin Ingestion on Liver Cancer Development Using an At-Risk Two-Staged Model of Mouse Hepatocarcinogenesis.
Igor Mrdjen, Jiyoung Lee, Christopher M Weghorst, Thomas J Knobloch

Toxins (Basel)· July 2022

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Acute cyanotoxin poisoning reveals a marginal effect on mouse gut microbiome composition but indicates metabolic shifts related to liver and gut inflammation.
Molly C Mills, Morgan V Evans, Seungjun Lee, Thomas Knobloch, Christopher Weghorst

Ecotoxicol Environ Saf· June 2021

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Microcystis toxin-mediated tumor promotion and toxicity lead to shifts in mouse gut microbiome.
Jiyoung Lee, Seungjun Lee, Alba Mayta, Igor Mrdjen, Christopher Weghorst

Ecotoxicol Environ Saf· December 2020

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Comparative Encapsulation Efficiency of Lutein in Micelles Synthesized via Batch and High Throughput Methods.
Lauren E Cosby, Kil Ho Lee, Thomas J Knobloch, Christopher M Weghorst, Jessica O Winter

Int J Nanomedicine· December 2020

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A Multi-level Model to Understand Cervical Cancer Disparities in Appalachia.
Electra D Paskett, Michael L Pennell, Mack T Ruffin, Christopher M Weghorst, Bo Lu

Cancer Prev Res (Phila)· March 2020

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Inherited alterations of TGF beta signaling components in Appalachian cervical cancers.
Thomas J Knobloch, Juan Peng, Erinn M Hade, David E Cohn, Mack T Ruffin, Logan C Weghorst, Christopher M Weghorst

Cancer Causes Control· October 2019

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Dietary administration of black raspberries modulates arsenic biotransformation and reduces urinary 8-oxo-2'-deoxyguanosine in mice.
Pengcheng Tu, Jingchuan Xue, Xiaoming Bian, Liang Chi, Bei Gao, Christopher M Weghorst

Toxicol Appl Pharmacol· August 2019

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Metabolic Regulation of Glycolysis and AMP Activated Protein Kinase Pathways during Black Raspberry-Mediated Oral Cancer Chemoprevention.
Thomas J Knobloch, Nathan M Ryan, Lei Bruschweiler-Li, Cheng Wang, Matthew C Bernier, Christopher M Weghorst

Metabolites· July 2019

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Impact of Microcystin-LR on Liver Function Varies by Dose and Sex in Mice.
Igor Mrdjen, Mark A Morse, Randall J Ruch, Thomas J Knobloch, Shambhunath Choudhary, Christopher M Weghorst

Toxins (Basel)· October 2018

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Storage conditions modulate the metabolomic profile of a black raspberry nectar with minimal impact on bioactivity.
Matthew D Teegarden, Thomas J Knobloch, Christopher M Weghorst, Jessica L Cooperstone, Devin G Peterson

Food Funct· September 2018

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Characterization of the Functional Changes in Mouse Gut Microbiome Associated with Increased Population Modulated by Dietary Black Raspberries.
Pengcheng Tu, Xiaoming Bian, Liang Chi, Bei Gao, Hongyu Ru, Christopher M Weghorst

ACS Omega· September 2018

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Inhibition of Pro-inflammatory and Anti-apoptotic Biomarkers during Experimental Oral Cancer Chemoprevention by Dietary Black Raspberries.
Steve Oghumu, Bruce C Casto, Jennifer Ahn-Jarvis, Logan C Weghorst, Jim Maloney, Christopher M Weghorst

Front Immunol· October 2017

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Deletion of macrophage migration inhibitory factor inhibits murine oral carcinogenesis: Potential role for chronic pro-inflammatory immune mediators.
Steve Oghumu, Thomas J Knobloch, Cesar Terrazas, Sanjay Varikuti, Jennifer Ahn-Jarvis, Christopher M Weghorst

Int J Cancer· September 2016

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Suppression of Proinflammatory and Prosurvival Biomarkers in Oral Cancer Patients Consuming a Black Raspberry Phytochemical-Rich Troche.
Thomas J Knobloch, Lana K Uhrig, Dennis K Pearl, Bruce C Casto, Blake M Warner, Christopher M Weghorst

Cancer Prev Res (Phila)· February 2016

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Alterations in RD(INK4/ARF) -mediated en bloc regulation of the INK4-ARF locus in human squamous cell carcinoma of the head and neck.
Ming J Poi, Thomas J Knobloch, Marta T Sears, Blake M Warner, Lana K Uhrig, Christopher M Weghorst

Mol Carcinog· July 2015

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Comprehensive evaluation of caspase-14 in vulvar neoplasia: an opportunity for treatment with black raspberry extract.
Amy S Joehlin-Price, Camille T Elkins, Julie A Stephens, David E Cohn, Thomas J Knobloch, Christopher M Weghorst

Gynecol Oncol· December 2014

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Chemoprevention of oral cancer by topical application of black raspberries on high at-risk mucosa.
Blake M Warner, Bruce C Casto, Thomas J Knobloch, Brent T Accurso, Christopher M Weghorst

Oral Surg Oral Med Oral Pathol Oral Radiol· December 2014

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Bioactive compounds or metabolites from black raspberries modulate T lymphocyte proliferation, myeloid cell differentiation and Jak/STAT signaling.
Thomas A Mace, Samantha A King, Zeenath Ameen, Omar Elnaggar, Gregory Young, Christopher M Weghorst

Cancer Immunol Immunother· September 2014

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Coordinated expression of cyclin-dependent kinase-4 and its regulators in human oral tumors.
Ming J Poi, Thomas J Knobloch, Marta T Sears, Lana K Uhrig, Blake M Warner, Christopher M Weghorst

Anticancer Res· July 2014

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Genetic alterations of RD(INK4/ARF) enhancer in human cancer cells.
Junan Li, Thomas J Knobloch, Ming J Poi, Zhaoxia Zhang, Andrew T Davis, Christopher M Weghorst

Mol Carcinog· March 2014

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The choice of reference gene affects statistical efficiency in quantitative PCR data analysis.
Yi Guo, Michael L Pennell, Dennis K Pearl, Thomas J Knobloch, Soledad Fernandez, Christopher M Weghorst

Biotechniques· October 2013

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The study of pH-dependent stability shows that the TPLH-mediated hydrogen-bonding network is important for the conformation and stability of human gankyrin.
Chunhua Yuan, Yi Guo, Lu Zhu, Wei Guo, Anjali Mahajan, Christopher M Weghorst

Biochemistry· July 2013

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Evidence that P12, a specific variant of P16(INK4A), plays a suppressive role in human pancreatic carcinogenesis.
Ming J Poi, Thomas J Knobloch, Chunhua Yuan, Ming-Daw Tsai, Christopher M Weghorst

Biochem Biophys Res Commun· June 2013

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Chemoprevention of mouse lung and colon tumors by suberoylanilide hydroxamic acid and atorvastatin.
Michael A Pereira, Blake M Warner, Thomas J Knobloch, Christopher M Weghorst, Ronald A Lubet

Int J Cancer· September 2012

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Gankyrin, a biomarker for epithelial carcinogenesis, is overexpressed in human oral cancer.
Junan Li, Thomas J Knobloch, Laura A Kresty, Zhaoxia Zhang, Jas C Lang, Christopher M Weghorst

Anticancer Res· September 2011

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