Publications by authors named "Christy Hung"

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Tau uptake by human neurons depends on receptor LRP1 and kinase LRRK2.
Lewis D Evans, Alessio Strano, Eleanor Tuck, Ashley Campbell, James Smith, Christy Hung

EMBO J· September 2025

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Mislocalization of nucleic acids is a convergent and targetable mechanism in Alzheimer's disease and frontotemporal dementia.
Christy Hung, Miriam Llorian, Koustav Pal, Frederick J Livesey, Jyoti Choudhary

Cell Rep· July 2025

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APP antisense oligonucleotides are effective in rescuing mitochondrial phenotypes in human iPSC-derived trisomy 21 astrocytes.
Srishruthi Thirumalai, Frederick J Livesey, Rickie Patani, Christy Hung

Alzheimers Dement· January 2025

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Clearance of beta-amyloid and tau aggregates is size dependent and altered by an inflammatory challenge.
Emre Fertan, Christy Hung, John S H Danial, Jeff Y L Lam, Pranav Preman

Brain Commun· December 2024

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APP antisense oligonucleotides reduce amyloid-β aggregation and rescue endolysosomal dysfunction in Alzheimer's disease.
Christy Hung, Emre Fertan, Frederick J Livesey, David Klenerman, Rickie Patani

Brain· July 2024

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Therapeutic potential of APP antisense oligonucleotides for Alzheimer's disease and down syndrome-related Alzheimer's disease.
Srishruthi Thirumalai, Rickie Patani, Christy Hung

Mol Neurodegener· July 2024

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4R tau drives endolysosomal and autophagy dysfunction in frontotemporal dementia.
Christy Hung, Rickie Patani

Autophagy· May 2024

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Elevated 4R tau contributes to endolysosomal dysfunction and neurodegeneration in VCP-related frontotemporal dementia.
Christy Hung, Rickie Patani

Brain· March 2024

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Endolysosome and autophagy dysfunction in Alzheimer disease.
Christy Hung, Frederick J Livesey

Autophagy· November 2021

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SORL1 deficiency in human excitatory neurons causes APP-dependent defects in the endolysosome-autophagy network.
Christy Hung, Eleanor Tuck, Victoria Stubbs, Sven J van der Lee, Cora Aalfs

Cell Rep· June 2021

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Importance of retrograde axonal transport in mitochondrial health and distribution.
Christy Hung

Cell Death Discov· May 2021

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Altered γ-Secretase Processing of APP Disrupts Lysosome and Autophagosome Function in Monogenic Alzheimer's Disease.
Christy O Y Hung, Frederick J Livesey

Cell Rep· December 2018

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Live-Cell Imaging Reveals Tau Isoforms Imbalance Disrupts Traffic of APP Vesicles in Human Neurons.
Christy Oi Ying Hung

J Neurosci· February 2017

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KIF1A mediates axonal transport of BACE1 and identification of independently moving cargoes in living SCG neurons.
Christy O Y Hung, Michael P Coleman

Traffic· November 2016

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