Publications by authors named "Chuanzheng Zhou"

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Systematic Study of the Impact of DNA Interstrand Cross-Links on Nucleosome Structure, Sliding, and Transcription.
Xiajing Shan, Jiahui Li, Jingke Ma, Xiaoyao Li, Qitong Liu, Chuanzheng Zhou

ACS Chem Biol· December 2025

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DNA - histone cross-link locks the nucleosome structure and disrupts its recognition and processing.
Xiajing Shan, Gaoyuan Ji, Jiahui Li, Mengtian Ren, Jingke Ma, Yifei Zhou, Chuanzheng Zhou

Protein Cell· November 2025

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C4'-Me-modified 2',3'-cGAMP elicits a robust innate immune response in cells harboring the loss-of-function hSTING-R232H variant.
Kuan Lu, Qiang Li, Wenli Guan, Jingke Ma, Yongchang Zhou, Yifei Zhou, Chuanzheng Zhou

Org Biomol Chem· October 2025

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Development of Thiol-Labile α-Amino Protecting Groups for Efficient Solid-Phase Peptide Synthesis.
Hongjun Li, Yifei Zhou, Linhai Yan, Xiang Zhu, Xinrui Tian, Chuanzheng Zhou

Chembiochem· September 2025

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Synthesis of 4'-SCF-Modified Ribonucleic Acid for Structural Probing by F Nuclear Magnetic Resonance Spectroscopy.
Chaochao Fan, Marko Trajkovski, Qiang Li, Yating Chen, Chaoyu Cui, Yifei Zhou, Chuanzheng Zhou

J Org Chem· August 2025

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Hetero-Selective Cross-Linking of Primary and Secondary Alkyl Amines with CS Under Ambient Aerobic Oxidation for Bioconjugation.
Shuai Jiang, Xin Chu, Xiangmei Kong, Xintao Miao, Xiaoxi Xu, Chuanzheng Zhou

Angew Chem Int Ed Engl· July 2025

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Annulative Editing of Peptide Side Chains: N-Pyridination of Lysine via Chichibabin Pyridine Synthesis in Hexafluoroisopropanol.
Shaokun Cai, Chengjin Wu, Zhang Zhang, Xin Chu, Xiaowei Sun, Chuanzheng Zhou

Org Lett· June 2025

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Homobifunctional Photocaged 2-Butene-1,4-dials (bis-PBDAs) as Amino-Reactive Photo-Crosslinkers for Biomaterial Fabrication and Cell Fixation.
Jiahui Li, Qi Wang, Mengyuan Yin, Xiajing Shan, Wenli Guan, Yifei Zhou, Chuanzheng Zhou

Chembiochem· April 2025

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Uridine Embedded within DNA is Repaired by Uracil DNA Glycosylase via a Mechanism Distinct from That of Ribonuclease H2.
Chaochao Fan, Xuelin Zhan, Fengmin Guo, Qiang Li, Kuan Lu, Yifei Zhou, Chuanzheng Zhou

J Am Chem Soc· April 2025

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Formamidine as an Easy-On and Easy-Off Linker for Reversible Crosslinking of Two Alkyl Amines in Peptide Stapling and Conjugation.
Xin Chu, Zhang Zhang, Xiaoxi Xu, Wenli Guan, Shuai Jiang, Chuanzheng Zhou

Angew Chem Int Ed Engl· March 2025

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Structural basis for human OGG1 processing 8-oxodGuo within nucleosome core particles.
Mengtian Ren, Fabian Gut, Yilan Fan, Jingke Ma, Xiajing Shan, Chuanzheng Zhou

Nat Commun· October 2024

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Peptide Stapling by Crosslinking Two Amines with α-Ketoaldehydes through Diverse Modified Glyoxal-Lysine Dimer Linkers.
Pan Guo, Xin Chu, Chengjin Wu, Tianjiao Qiao, Wenli Guan, Chuanzheng Zhou

Angew Chem Int Ed Engl· April 2024

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synthesis of quantum dots in the nucleus of live cells.
Yusi Hu, Zhi-Gang Wang, Haohao Fu, Chuanzheng Zhou, Wensheng Cai

Natl Sci Rev· March 2024

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Photo-caged 2-butene-1,4-dial as an efficient, target-specific photo-crosslinker for covalent trapping of DNA-binding proteins.
Jiahui Li, Zenghui Cui, Chaochao Fan, Yifei Zhou, Mengtian Ren, Chuanzheng Zhou

Chem Sci· October 2023

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Suppression of alpha-carbon racemization in peptide synthesis based on a thiol-labile amino protecting group.
Yifei Zhou, Hongjun Li, Yi Huang, Jiahui Li, Guiyu Deng, Chuanzheng Zhou

Nat Commun· September 2023

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Bioconjugation via Hetero-Selective Clamping of Two Different Amines with ortho-Phthalaldehyde.
Xin Chu, Bo Li, Hao-Yang Liu, Xiaowei Sun, Xiaochen Yang, Chuanzheng Zhou

Angew Chem Int Ed Engl· January 2023

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4'-SCF -Labeling Constitutes a Sensitive F NMR Probe for Characterization of Interactions in the Minor Groove of DNA.
Qiang Li, Marko Trajkovski, Chaochao Fan, Jialiang Chen, Yifei Zhou, Chuanzheng Zhou

Angew Chem Int Ed Engl· November 2022

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Participation of Histones in DNA Damage and Repair within Nucleosome Core Particles: Mechanism and Applications.
Mengtian Ren, Marc M Greenberg, Chuanzheng Zhou

Acc Chem Res· April 2022

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2',3'-Cyclic GMP-AMP Dinucleotides for STING-Mediated Immune Modulation: Principles, Immunotherapeutic Potential, and Synthesis.
Mengdi Shang, Kuan Lu, Wenli Guan, Shujie Cao, Mengtian Ren, Chuanzheng Zhou

ChemMedChem· January 2022

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Nucleosomes enter cells by clathrin- and caveolin-dependent endocytosis.
Huawei Wang, Xiajing Shan, Mengtian Ren, Mengdi Shang, Chuanzheng Zhou

Nucleic Acids Res· December 2021

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C4'-Fluorinated Oligodeoxynucleotides: Synthesis, Stability, Structural Studies.
Yifei Zhou, Kuan Lu, Qiang Li, Chaochao Fan, Chuanzheng Zhou

Chemistry· October 2021

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Designing in vivo active DNAzymes.
Yifei Zhou, Chuanzheng Zhou

Nat Chem· April 2021

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Histones participate in base excision repair of 8-oxodGuo by transiently cross-linking with active repair intermediates in nucleosome core particles.
Mengtian Ren, Mengdi Shang, Huawei Wang, Zhen Xi, Chuanzheng Zhou

Nucleic Acids Res· January 2021

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Cellular uptake of extracellular nucleosomes induces innate immune responses by binding and activating cGMP-AMP synthase (cGAS).
Huawei Wang, Chuanlong Zang, Mengtian Ren, Mengdi Shang, Zhenghua Wang, Chuanzheng Zhou

Sci Rep· September 2020

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Cysteine-specific protein multi-functionalization and disulfide bridging using 3-bromo-5-methylene pyrrolones.
Yingqian Zhang, Chuanlong Zang, Guoce An, Mengdi Shang, Zenghui Cui, Chuanzheng Zhou

Nat Commun· February 2020

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