Publications by authors named "Chukwuma Agu"

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Novel stem cell technologies are powerful tools to understand the impact of human factors on malaria.
Alena Pance, Bee L Ng, Kioko Mwikali, Manousos Koutsourakis, Chukwuma Agu

Front Cell Infect Microbiol· January 2024

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A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage.
Xueqing Zou, Gene Ching Chiek Koh, Arjun Scott Nanda, Andrea Degasperi, Katie Urgo, Chukwuma A Agu

Nat Cancer· June 2021

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Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2.
Subhankar Mukhopadhyay, Eva Heinz, Immacolata Porreca, Kaur Alasoo, Amy Yeung, Chukwuma A Agu

J Exp Med· February 2020

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Human blood vessel organoids as a model of diabetic vasculopathy.
Reiner A Wimmer, Alexandra Leopoldi, Martin Aichinger, Nikolaus Wick, Brigitte Hantusch, Chukwuma A Agu

Nature· January 2019

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Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.
Joshi Stephen, Sheela Nampoothiri, Aditi Banerjee, Nathanial J Tolman, Josef Martin Penninger, Chukwuma A Agu

Hum Genet· April 2018

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A reversible haploid mouse embryonic stem cell biobank resource for functional genomics.
Ulrich Elling, Reiner A Wimmer, Andreas Leibbrandt, Thomas Burkard, Georg Michlits, Chukwuma A Agu

Nature· October 2017

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Common genetic variation drives molecular heterogeneity in human iPSCs.
Helena Kilpinen, Angela Goncalves, Andreas Leha, Vackar Afzal, Kaur Alasoo, Chukwuma A Agu

Nature· June 2017

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Corrigendum: Common genetic variation drives molecular heterogeneity in human iPSCs.
Helena Kilpinen, Angela Goncalves, Andreas Leha, Vackar Afzal, Kaur Alasoo, Chukwuma A Agu

Nature· June 2017

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Successful Generation of Human Induced Pluripotent Stem Cell Lines from Blood Samples Held at Room Temperature for up to 48 hr.
Chukwuma A Agu, Filipa A C Soares, Alex Alderton, Minal Patel, Rizwan Ansari

Stem Cell Reports· October 2015

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Toxin Kid uncouples DNA replication and cell division to enforce retention of plasmid R1 in Escherichia coli cells.
Belén Pimentel, Radhika Nair, Camino Bermejo-Rodríguez, Mark A Preston, Chukwuma A Agu

Proc Natl Acad Sci U S A· February 2014

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Bacteriophage-encoded toxins: the lambda-holin protein causes caspase-independent non-apoptotic cell death of eukaryotic cells.
Chukwuma A Agu, Reinhard Klein, Johannes Lengler, Franz Schilcher, Wolfgang Gregor

Cell Microbiol· July 2007

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The cytotoxic activity of the bacteriophage lambda-holin protein reduces tumour growth rates in mammary cancer cell xenograft models.
Chukwuma A Agu, Reinhard Klein, Sonja Schwab, Marielle König-Schuster, Petra Kodajova

J Gene Med· February 2006

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