Publications by authors named "Chul Yu"

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The search for pyruvate kinase-R activators; from a HTS screening hit via an impurity to the discovery of a lead series.
Chul Yu, Lina Quattrocchio Setti, Shahul Nilar, Zhe Li, Ming Yu

Bioorg Med Chem Lett· September 2024

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Structures of full-length plasma kallikrein bound to highly specific inhibitors describe a new mode of targeted inhibition.
James R Partridge, Rebeca M Choy, Abel Silva-Garcia, Chul Yu, Zhe Li

J Struct Biol· May 2019

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Evaluation of [(18)F]-CP18 as a PET imaging tracer for apoptosis.
Helen Su, Gang Chen, Umesh Gangadharmath, Luis F Gomez, Qianwa Liang, Chul Yu

Mol Imaging Biol· December 2013

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[(18)F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease.
Chun-Fang Xia, Janna Arteaga, Gang Chen, Umesh Gangadharmath, Luis F Gomez, Chul Yu

Alzheimers Dement· November 2013

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A highly selective and specific PET tracer for imaging of tau pathologies.
Wei Zhang, Janna Arteaga, Daniel K Cashion, Gang Chen, Umesh Gangadharmath, Chul Yu

J Alzheimers Dis· May 2013

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Discovery and Development of Potent LFA-1/ICAM-1 Antagonist SAR 1118 as an Ophthalmic Solution for Treating Dry Eye.
Min Zhong, Thomas R Gadek, Minna Bui, Wang Shen, John Burnier, Chul H Yu

ACS Med Chem Lett· March 2012

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Structure-activity relationship (SAR) of the α-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists.
Min Zhong, Emily J Hanan, Wang Shen, Minna Bui, Michelle R Arkin, Chul H Yu

Bioorg Med Chem Lett· January 2011

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Discovery of tetrahydroisoquinoline (THIQ) derivatives as potent and orally bioavailable LFA-1/ICAM-1 antagonists.
Min Zhong, Wang Shen, Kenneth J Barr, Jennifer P Arbitrario, Michelle R Arkin, Chul H Yu

Bioorg Med Chem Lett· September 2010

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2-Aminobenzimidazoles as potent Aurora kinase inhibitors.
Min Zhong, Minna Bui, Wang Shen, Subramanian Baskaran, Darin A Allen, Chul H Yu

Bioorg Med Chem Lett· September 2009

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Water-soluble prodrugs of an Aurora kinase inhibitor.
Johan D Oslob, Stacey A Heumann, Chul H Yu, Darin A Allen, Subramanian Baskaran

Bioorg Med Chem Lett· March 2009

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Discovery of a potent and selective aurora kinase inhibitor.
Johan D Oslob, Michael J Romanowski, Darin A Allen, Subramanian Baskaran, Minna Bui, Chul H Yu

Bioorg Med Chem Lett· September 2008

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Knockout of a starch synthase gene OsSSIIIa/Flo5 causes white-core floury endosperm in rice (Oryza sativa L.).
Nayeon Ryoo, Chul Yu, Cheon-Seok Park, Moo-Yeol Baik, In Myoung Park

Plant Cell Rep· July 2007

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Identification of nonpeptidic small-molecule inhibitors of interleukin-2.
Nathan D Waal, Wenjin Yang, Johan D Oslob, Michelle R Arkin, Jennifer Hyde, Chul H Yu

Bioorg Med Chem Lett· February 2005

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Integrating fragment assembly and biophysical methods in the chemical advancement of small-molecule antagonists of IL-2: an approach for inhibiting protein-protein interactions.
Brian C Raimundo, Johan D Oslob, Andrew C Braisted, Jennifer Hyde, Robert S McDowell, Chul H Yu

J Med Chem· June 2004

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Benzimidazolone p38 inhibitors.
Mark A Dombroski, Michael A Letavic, Kim F McClure, John T Barberia, Thomas J Carty, Chul H Yu

Bioorg Med Chem Lett· February 2004

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Synthesis and biological activity of piperazine-based dual MMP-13 and TNF-alpha converting enzyme inhibitors.
Michael A Letavic, John T Barberia, Thomas J Carty, Joel R Hardink, Jennifer Liras, Chul H Yu

Bioorg Med Chem Lett· October 2003

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Discovery of a potent small molecule IL-2 inhibitor through fragment assembly.
Andrew C Braisted, Johan D Oslob, Warren L Delano, Jennifer Hyde, Robert S McDowell, Chul Yu

J Am Chem Soc· April 2003

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Synthesis and biological activity of selective pipecolic acid-based TNF-alpha converting enzyme (TACE) inhibitors.
Michael A Letavic, Matt Z Axt, John T Barberia, Thomas J Carty, Dennis E Danley, Chul H Yu

Bioorg Med Chem Lett· May 2002

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