Publications by authors named "Chulhee Choi"

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Safety and Anti-Inflammatory Effects of Engineered Extracellular Vesicles (ILB-202) for NF-κB Inhibition: A Double-Blind, Randomized, Placebo-Controlled Phase 1 Trial.
Seoyeon Hyun, Hojun Choi, Yujin Sub, Dasom Hong, So-Hee Ahn, Kyungsun Choi, Chulhee Choi

J Extracell Vesicles· September 2025

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Single-cell analysis of the decidua unveils the mechanism of anti-inflammatory exosomes for chorioamnionitis in nonhuman primates.
Seung Hyun Jang, Hojun Choi, Eun Mi Lee, Seung-Bin Yoon, Hye-Jung Kim, Chulhee Choi

Sci Adv· July 2025

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Speech Recognition in Real-Life Background Noise by Young and Middle-Aged Adults with Normal Hearing.
Ji Young Lee, Jin Tae Lee, Hye Jeong Heo, Chul-Hee Choi, Seong Hee Choi

J Audiol Otol· April 2025

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Exosome-based targeted delivery of NF-κB ameliorates age-related neuroinflammation in the aged mouse brain.
Chae-Jeong Lee, Seung Hyun Jang, Jiwoo Lim, Hyunju Park, So-Hee Ahn, Chulhee Choi, Youn-Hee Choi

Exp Mol Med· February 2025

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Engineered Exosomes Carrying Super-Repressor IκB Reduced Biliary Atresia-Induced Liver Fibrosis in Minipig and Mouse Models.
Jisoo Kang, Cheolhyoung Park, Hanoul Yun, Chulhee Choi, Wonhyo Seo

Pharmaceutics· February 2025

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Exploring the clinical transition of engineered exosomes designed for intracellular delivery of therapeutic proteins.
Minseong Kim, Hojun Choi, Deok-Jin Jang, Hye-Jung Kim, Yujin Sub, Chulhee Choi

Stem Cells Transl Med· July 2024

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Effects of NF-κB Inhibitor on Sepsis Depend on the Severity and Phase of the Animal Sepsis Model.
Ye Jin Park, Jinkun Bae, Jae-Kwang Yoo, So-Hee Ahn, Seon Young Park, Chulhee Choi

J Pers Med· June 2024

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Exosome-mediated delivery of super-repressor IκBα alleviates inflammation and joint damages in rheumatoid arthritis.
Hae-In Lee, Min-Joo Ahn, Jae-Kwang Yoo, So-Hee Ahn, Seon Young Park, Chulhee Choi

Arthritis Res Ther· January 2024

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Efficacy of Allogeneic and Xenogeneic Exosomes for the Treatment of Canine Atopic Dermatitis: A Pilot Study.
Sang-Won Kim, Kyung-Min Lim, Ssang-Goo Cho, Bokyeong Ryu, C-Yoon Kim, Chulhee Choi

Animals (Basel)· January 2024

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Discovering the anti-cancer phytochemical rutin against breast cancer through the methodical platform based on traditional medicinal knowledge.
Jungwhoi Lee, Jungsul Lee, WooGwang Sim, Jae-Hoon Kim, Chulhee Choi

BMB Rep· November 2023

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A report on the International Society for Cell & Gene Therapy 2022 Scientific Signature Series, "Therapeutic advances with native and engineered human extracellular vesicles".
Wei Seong Toh, Reza Yarani, Samir El Andaloussi, Byong Seung Cho, Chulhee Choi

Cytotherapy· August 2023

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The Effect of Super-Repressor IkB-Loaded Exosomes (Exo-srIκBs) in Chronic Post-Ischemia Pain (CPIP) Models.
Ji Seon Chae, Hyunju Park, So-Hee Ahn, Eun-Chong Han, Yoonjin Lee, Chulhee Choi, Youn-Hee Choi

Pharmaceutics· February 2023

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Exosome-Based Delivery of Super-Repressor IκBα Alleviates Alcohol-Associated Liver Injury in Mice.
Hee-Hoon Kim, Young-Ri Shim, Sung Eun Choi, Tolulope Esther Falana, Jae-Kwang Yoo, Chulhee Choi

Pharmaceutics· February 2023

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Differential dependency of human glioblastoma cells on vascular endothelial growth factor‑A signaling via neuropilin‑1.
Jungwhoi Lee, Kyuha Chong, Jungsul Lee, Chungyeul Kim, Jae-Hoon Kim, Kyungsun Choi, Chulhee Choi

Int J Oncol· October 2022

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Atypical induction of HIF-1α expression by pericellular Notch1 signaling suffices for the malignancy of glioblastoma multiforme cells.
Jungwhoi Lee, Eunsoo Kim, Kyuha Chong, Seung-Wook Ryu, Chungyeul Kim, Kyungsun Choi, Chulhee Choi

Cell Mol Life Sci· October 2022

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Manufacturing Therapeutic Exosomes: from Bench to Industry.
So-Hee Ahn, Seung-Wook Ryu, Hojun Choi, Sangmin You, Jun Park, Chulhee Choi

Mol Cells· May 2022

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Quantitative Biodistribution and Pharmacokinetics Study of GMP-Grade Exosomes Labeled with Zr Radioisotope in Mice and Rats.
Hojun Choi, Myung-Yoon Kim, Dae-Hwan Kim, Hanoul Yun, Byung-Koo Oh, Chulhee Choi

Pharmaceutics· May 2022

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Strategies for Targeted Delivery of Exosomes to the Brain: Advantages and Challenges.
Hojun Choi, Kyungsun Choi, Dae-Hwan Kim, Byung-Koo Oh, Hwayoung Yim, Chulhee Choi

Pharmaceutics· March 2022

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Targeted Delivery of Exosomes Armed with Anti-Cancer Therapeutics.
Hojun Choi, Hwayoung Yim, Cheolhyoung Park, So-Hee Ahn, Yura Ahn, Chulhee Choi

Membranes (Basel)· January 2022

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Therapeutic exosomes for various human diseases: Special issue of BMB Reports in 2022.
Chulhee Choi

BMB Rep· January 2022

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Exosome-based delivery of super-repressor IκBα ameliorates kidney ischemia-reperfusion injury.
Seonghun Kim, Sul A Lee, Heakyung Yoon, Myung Yoon Kim, Jae-Kwang Yoo, Chulhee Choi

Kidney Int· September 2021

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Biodistribution of Exosomes and Engineering Strategies for Targeted Delivery of Therapeutic Exosomes.
Hojun Choi, Yoorim Choi, Hwa Young Yim, Amin Mirzaaghasi, Jae-Kwang Yoo, Chulhee Choi

Tissue Eng Regen Med· August 2021

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Extracellular vesicles in kidneys and their clinical potential in renal diseases.
Sul A Lee, Chulhee Choi, Tae-Hyun Yoo

Kidney Res Clin Pract· June 2021

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Platform technologies and human cell lines for the production of therapeutic exosomes.
Jiyoon Kim, Yonghee Song, Cheol Hyoung Park, Chulhee Choi

Extracell Vesicles Circ Nucl Acids· March 2021

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Biodistribution and Pharmacokinectics of Liposomes and Exosomes in a Mouse Model of Sepsis.
Amin Mirzaaghasi, Yunho Han, So-Hee Ahn, Chulhee Choi, Ji-Ho Park

Pharmaceutics· March 2021

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