Publications by authors named "Chuling Zhuang"

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PTPN22-CD45 dual phosphatase retrograde feedback enhances TCR signaling and autoimmunity.
Shen Yang, Eugenio Santelli, Carlos G Gonzalez, Wade T Johnson, Irene V Choi, Chuling Zhuang

Sci Adv· September 2025

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Targeting tGLI1, a novel mediator of tumor therapeutic resistance, using Ketoconazole sensitizes glioblastoma to CDK4/6 therapy and chemoradiation.
Yang Yu, Austin Arrigo, Ankush Chandra, Chuling Zhuang, Mariana K Najjar

bioRxiv· February 2025

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Co-Inhibition of tGLI1 and GP130 Using FDA-Approved Ketoconazole and Bazedoxifene Is Synergistic Against the Growth and Metastasis of HER2-Enriched and Triple-Negative Breast Cancers.
Sara Manore, Chuling Zhuang, Mariana K Najjar, Grace L Wong, Shivani Bindal

Cells· December 2024

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Interleukin-1 Receptor-Associated Kinase 1 in Cancer Metastasis and Therapeutic Resistance: Mechanistic Insights and Translational Advances.
Mariana K Najjar, Munazza S Khan, Chuling Zhuang, Ankush Chandra, Hui-Wen Lo

Cells· October 2024

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Dual inhibition of the TrkA and JAK2 pathways using entrectinib and pacritinib suppresses the growth and metastasis of HER2-positive and triple-negative breast cancers.
Angelina T Regua, Shivani Bindal, Mariana K Najjar, Chuling Zhuang, Munazza Khan

Cancer Lett· August 2024

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Crosstalk between breast cancer-derived microRNAs and brain microenvironmental cells in breast cancer brain metastasis.
Munazza S Khan, Grace L Wong, Chuling Zhuang, Mariana K Najjar, Hui-Wen Lo

Front Oncol· August 2024

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A novel gain-of-function phosphorylation site modulates PTPN22 inhibition of TCR signaling.
Chuling Zhuang, Shen Yang, Carlos G Gonzalez, Richard I Ainsworth, Sheng Li

J Biol Chem· June 2024

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