Publications by authors named "Chuxia Deng"

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Proteasomes suppress anticancer drug-induced cytotoxicity by inhibiting mitochondrial protein import and promoting ROS-BNIP3-mediated mitophagy.
Ling Li, Yangyang Feng, Jingbo Zhou, Fangyuan Shao, Yuzhong Peng, Chu-Xia Deng

Drug Resist Updat· November 2025

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Synergistic Effects of Radiotherapy and PD‑1 Blockade in a Human‑Mimetic BRCAness Model of Triple-Negative Breast Cancer.
Eun Ju Cho, Min Kyung Ki, Hye Jung Baek, Dong Hoon Shin, Eun Jung Park, Chu-Xia Deng

Int J Biol Sci· November 2025

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Proteasome: Role in T Cell Function Regulation.
Dongyang Tang, Xiaoran Wu, Josh Haipeng Lei, Yunfeng Qiao, Chu-Xia Deng

Int J Biol Sci· November 2025

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PTEN-deficient, chromosomal instability colorectal cancer is hypersensitive to STAT3 inhibition.
Guowen Ren, Yue Pu, Xiumei Zhang, Jinghong Chen, Eun Ju Yang, Chuxia Deng

Int J Biol Sci· November 2025

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The hemagglutinin-like proteins of basal vertebrate influenza-like viruses exhibit sialic-acid receptor binding disparity and their structural bases.
Di Zhang, Kefang Liu, Yufeng Xie, Junqing Sun, Wei Zhang, Chuxia Deng

PLoS Pathog· November 2025

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RAD51B-EZH2 axis as a potential therapeutic target for TNBC through cell fate conversion.
Shiqi Lin, Dongyang Tang, Josh Haipeng Lei, Xiangpeng Chu, Lijian Wang, Chuxia Deng

Cell Death Dis· November 2025

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Lars2-signaling mediates platinum resistance by accumulating cancer stem cell population and suppressing anti-tumor immunity.
Yuqing Wang, Min Deng, Haipeng Lei, Kai Miao, Xiaodong Shu, Chuxia Deng

Drug Resist Updat· November 2025

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CDK4/6 Inhibition Induces CD8 T Cell Antitumor Immunity via MIF-Induced Functional Orchestration of Tumor-Associated Macrophages.
Lin He, Yuzhong Peng, Lat-Lun Leong, Jingbo Zhou, Dongyang Tang, Chu-Xia Deng

Adv Sci (Weinh)· October 2025

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Liquid biopsy-based multi-cancer early detection: an exploration road from evidence to implementation.
Yongjie Xu, Sibo Zhu, Changfa Xia, Hui Yu, Si Shi, Chuxia Deng

Sci Bull (Beijing)· September 2025

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Suppressing protein damage response to overcome multidrug resistance in cancer therapy.
Fangyuan Shao, Zongjie Li, Hao Xiao, Yujun Chen, Yuheng Zhang, Chu-Xia Deng

Cell Discov· September 2025

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Reciprocal stabilization of CtBP and TRIM28 represses autophagy to promote metastasis.
Lixin Tai, Dongliang Zhu, Ping Tang, Jiajia Li, Junyi Li, Chuxia Deng

Nat Struct Mol Biol· August 2025

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CX1/BtSY2 and BANAL-20-52 exhibit broader receptor binding and higher affinities to multiple animal ACE2 orthologs than SARS-CoV-2 prototype.
Zepeng Xu, Linjie Li, Yuhang Gu, Dedong Li, Jianxun Qi, Chu-Xia Deng

J Virol· August 2025

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Manipulation of magnetic edge states in carbon quantum dots for magnetic resonance imaging and NIR-II photo-thermoelectric therapy.
Tesen Zhang, Quansheng Cheng, Hongwei Cheng, Qingcheng Wang, Bingzhe Wang, Chuxia Deng

Nat Commun· July 2025

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Orchestration of Tumor-Associated Macrophages in the Tumor Cell-Macrophage-CD8 T Cell Loop for Cancer Immunotherapy.
Lin He, Paul Kwong-Hang Tam, Chu-Xia Deng

Int J Biol Sci· July 2025

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Augment proteasome inhibitor efficacy activates CD8 T cell-mediated antitumor immunity in breast cancer.
Dongyang Tang, Shiqi Lin, Jingbo Zhou, Josh Haipeng Lei, Fangyuan Shao, Chu-Xia Deng

Cell Rep Med· July 2025

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Inhibition of mTOR attenuates the initiation and progression of BRCA1-associated mammary tumors.
Hye Jung Baek, Geun Hee Han, Eun Joo Cho, Jihao Xu, Min Kyung Ki, Chu-Xia Deng

Cancer Commun (Lond)· April 2025

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Establishing a cryopreserved biobank of living tumor tissues for drug sensitivity testing.
Ping Chen, Jing-Bo Zhou, Xiang-Peng Chu, Yang-Yang Feng, Qi-Bing Zeng, Chu-Xia Deng

Bioact Mater· April 2025

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Alkaline Adjuvant Regulates Proteolytic Activity of Macrophages for Antigen Cross-Presentation and Potentiates Radioimmunotherapy.
Bei Li, Yan Tan, Josh Haipeng Lei, Min Deng, Xinwang Yu, Chu-Xia Deng

Adv Mater· March 2025

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Lymphatic system is the mainstream for breast cancer dissemination and metastasis revealed by single-cell lineage tracing.
Kai Miao, Aiping Zhang, Xiaodan Yang, Yipeng Zhang, Anqi Lin, Chu-Xia Deng

Mol Cancer· March 2025

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Oncogenic activation of SMYD3-SHCBP1 promotes breast cancer development and is coupled with resistance to immune therapy.
Lihua Mo, Min Deng, Ragini Adhav, Yuni Chan, Josh Haipeng Lei, Chu-Xia Deng

Cell Death Dis· March 2025

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SRSF3 is oncogenic in breast but tumor-suppressive in liver by differential regulation of gene expression.
Lulu Yu, Masahiko Ajiro, Alexei Lobanov, Maggie Cam, Vladimir Majerciak, Chu-Xia Deng

bioRxiv· March 2025

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Susceptibility of Mitophagy-Deficient Tumors to Ferroptosis Induction by Relieving the Suppression of Lipid Peroxidation.
Shan Liu, Jing-Hong Chen, Li-Chao Li, Zhi-Peng Ye, Jian-Nan Liu, Chu-Xia Deng, Rong Deng

Adv Sci (Weinh)· February 2025

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Cancer can be a purely epigenetic disorder.
Ya Meng, Heng Sun, Chu-Xia Deng

Int J Biol Sci· January 2025

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Bubble-Inspired Multifunctional Magnetic Microrobots for Integrated Multidimensional Targeted Biosensing.
Zichen Xu, Heng Sun, Yuanhe Chen, Hon Ho Yu, Chu-Xia Deng

Nano Lett· November 2024

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YTHDF2 upregulation and subcellular localization dictate CD8 T cell polyfunctionality in anti-tumor immunity.
Haiyan Zhang, Xiaojing Luo, Wei Yang, Zhiying Wu, Zhicong Zhao, Chu-Xia Deng

Nat Commun· November 2024

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