Publications by authors named "Ciaran D Scallan"

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Self-amplifying mRNA expressing COBRA hemagglutinin elicits long-lasting, broadly reactive antibodies against seasonal influenza A viruses.
Spencer R Pierce, Hua Shi, Camila Caetano, David A Prots, Michael A Carlock, Ciaran D Scallan

Vaccine· August 2025

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Differential shaping of T cell responses elicited by heterologous ChAd68/self-amplifying mRNA SIV vaccine in macaques in combination with αCTLA4, αPD-1, or FLT3R agonist.
Amy R Rappaport, Elena Bekerman, Gregory R Boucher, Janette Sung, Brian Carr, Ciaran D Scallan

J Immunol· March 2025

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A shared neoantigen vaccine combined with immune checkpoint blockade for advanced metastatic solid tumors: phase 1 trial interim results.
Amy R Rappaport, Chrisann Kyi, Monica Lane, Meghan G Hart, Melissa L Johnson, Ciaran D Scallan

Nat Med· April 2024

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GRT-R910: a self-amplifying mRNA SARS-CoV-2 vaccine boosts immunity for ≥6 months in previously-vaccinated older adults.
Christine D Palmer, Ciaran D Scallan, Lauren D Kraemer Tardif, Melissa A Kachura, Amy R Rappaport

Nat Commun· June 2023

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Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results.
Christine D Palmer, Amy R Rappaport, Matthew J Davis, Meghan G Hart, Ciaran D Scallan

Nat Med· August 2022

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Low-dose self-amplifying mRNA COVID-19 vaccine drives strong protective immunity in non-human primates against SARS-CoV-2 infection.
Amy R Rappaport, Sue-Jean Hong, Ciaran D Scallan, Leonid Gitlin, Arvin Akoopie

Nat Commun· June 2022

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Orally administered adenoviral-based vaccine induces respiratory mucosal memory and protection against RSV infection in cotton rats.
Christina Joyce, Ciaran D Scallan, Roberto Mateo, Robert B Belshe, Sean N Tucker

Vaccine· July 2018

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Oral Modeling of an Adenovirus-Based Quadrivalent Influenza Vaccine in Ferrets and Mice.
Ciaran D Scallan, Jonathan D Lindbloom, Sean N Tucker

Infect Dis Ther· June 2016

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Oral administration of an adenovirus vector encoding both an avian influenza A hemagglutinin and a TLR3 ligand induces antigen specific granzyme B and IFN-γ T cell responses in humans.
Wendy Peters, Jennifer R Brandl, Jonathan D Lindbloom, C Josefina Martinez, Ciaran D Scallan

Vaccine· March 2013

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An adenovirus-based vaccine with a double-stranded RNA adjuvant protects mice and ferrets against H5N1 avian influenza in oral delivery models.
Ciaran D Scallan, Debora W Tingley, Jonathan D Lindbloom, James S Toomey, Sean N Tucker

Clin Vaccine Immunol· January 2013

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Oral adenoviral-based vaccines: historical perspective and future opportunity.
Sean N Tucker, Debora W Tingley, Ciaran D Scallan

Expert Rev Vaccines· February 2008

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Effects of transient immunosuppression on adenoassociated, virus-mediated, liver-directed gene transfer in rhesus macaques and implications for human gene therapy.
Haiyan Jiang, Linda B Couto, Susannah Patarroyo-White, Tongyao Liu, Dea Nagy, Ciaran D Scallan

Blood· November 2006

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Multiyear therapeutic benefit of AAV serotypes 2, 6, and 8 delivering factor VIII to hemophilia A mice and dogs.
Haiyan Jiang, David Lillicrap, Susannah Patarroyo-White, Tongyao Liu, Xiaobing Qian, Ciaran D Scallan

Blood· July 2006

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Human immunoglobulin inhibits liver transduction by AAV vectors at low AAV2 neutralizing titers in SCID mice.
Ciaran D Scallan, Haiyan Jiang, Tongyao Liu, Susannah Patarroyo-White, Jurg M Sommer

Blood· March 2006

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Improved coagulation in bleeding disorders by Non-Anticoagulant Sulfated Polysaccharides (NASP).
Tongyao Liu, Ciaran D Scallan, George J Broze, Susanna Patarroyo-White, Glenn F Pierce

Thromb Haemost· January 2006

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Phenotypic correction of a mouse model of hemophilia A using AAV2 vectors encoding the heavy and light chains of FVIII.
Ciaran D Scallan, Tongyao Liu, Amy E Parker, Susannah L Patarroyo-White, Haifeng Chen

Blood· December 2003

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Sustained phenotypic correction of canine hemophilia A using an adeno-associated viral vector.
Ciaran D Scallan, David Lillicrap, Haiyan Jiang, Xiaobing Qian, Susannah L Patarroyo-White

Blood· September 2003

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