Publications by authors named "Cihangir Duy"

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IRE1α-XBP1 safeguards hematopoietic stem and progenitor cells by restricting pro-leukemogenic gene programs.
Brendan M Barton, Francheska Son, Akanksha Verma, Saswat Kumar Bal, Qianzi Tang, Cihangir Duy

Nat Immunol· February 2025

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Epigenetic balance ensures mechanistic control of MLL amplification and rearrangement.
Zach H Gray, Damayanti Chakraborty, Reuben R Duttweiler, Gulnaz D Alekbaeva, Sedona E Murphy, Cihangir Duy

Cell· October 2023

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(R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in IDH-Mutant Cancers.
Kathryn Gunn, Matti Myllykoski, John Z Cao, Manna Ahmed, Bofu Huang, Cihangir Duy

Cancer Discov· June 2023

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Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival.
Meng Li, Matthew R Teater, Jun Young Hong, Noel R Park, Cihangir Duy

Blood Cancer Discov· January 2022

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Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence.
Cihangir Duy, Meng Li, Matt Teater, Cem Meydan, Francine E Garrett-Bakelman

Cancer Discov· June 2021

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Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia.
Barry M Zee, Kamrine E Poels, Cong-Hui Yao, Kimihito C Kawabata, Gongwei Wu, Cihangir Duy

iScience· June 2021

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An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence.
Eugen Dhimolea, Ricardo de Matos Simoes, Dhvanir Kansara, Aziz Al'Khafaji, Juliette Bouyssou, Cihangir Duy

Cancer Cell· February 2021

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Epigenetic Mechanisms in Leukemias and Lymphomas.
Cihangir Duy, Wendy Béguelin, Ari Melnick

Cold Spring Harb Perspect Med· December 2020

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Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML.
Cihangir Duy, Matt Teater, Francine E Garrett-Bakelman, Tak C Lee, Cem Meydan

Cancer Discov· July 2019

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Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis.
Meng Li, Ying-Ling Chiang, Costas A Lyssiotis, Matthew R Teater, Jun Young Hong, Cihangir Duy

Cancer Cell· June 2019

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Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis.
Katerina Hatzi, Huimin Geng, Ashley S Doane, Cem Meydan, Reed LaRiviere, Cihangir Duy

Nat Immunol· January 2019

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Untangling the Role of Polycomb Complexes in Chemotherapy Resistance.
Cihangir Duy, Ari Melnick

Cancer Discov· November 2018

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ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia.
Tamara Maes, Cristina Mascaró, Iñigo Tirapu, Angels Estiarte, Filippo Ciceri, Cihangir Duy

Cancer Cell· March 2018

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Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia.
Stephen S Chung, Eunhee Kim, Jae H Park, Young Rock Chung, Piro Lito, Cihangir Duy

Sci Transl Med· May 2014

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BACH2-BCL6 balance regulates selection at the pre-B cell receptor checkpoint.
Srividya Swaminathan, Cihangir Duy, Markus Müschen

Trends Immunol· March 2014

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Pre-B cell receptor-mediated activation of BCL6 induces pre-B cell quiescence through transcriptional repression of MYC.
Rahul Nahar, Parham Ramezani-Rad, Maximilian Mossner, Cihangir Duy, Leandro Cerchietti

Blood· October 2011

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BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition.
Cihangir Duy, Christian Hurtz, Seyedmehdi Shojaee, Leandro Cerchietti, Huimin Geng

Nature· May 2011

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BCL6 is critical for the development of a diverse primary B cell repertoire.
Cihangir Duy, J Jessica Yu, Rahul Nahar, Srividya Swaminathan, Soo-Mi Kweon

J Exp Med· June 2010

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The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia.
Lars Klemm, Cihangir Duy, Ilaria Iacobucci, Stefan Kuchen, Gregor von Levetzow

Cancer Cell· September 2009

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Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function.
Daniel Trageser, Ilaria Iacobucci, Rahul Nahar, Cihangir Duy, Gregor von Levetzow

J Exp Med· August 2009

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Activation-induced cytidine deaminase acts as a mutator in BCR-ABL1-transformed acute lymphoblastic leukemia cells.
Niklas Feldhahn, Nadine Henke, Kai Melchior, Cihangir Duy, Bonaventure Ndikung Soh

J Exp Med· May 2007

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Thermostability of irreversible unfolding alpha-amylases analyzed by unfolding kinetics.
Cihangir Duy, Jörg Fitter

J Biol Chem· November 2005

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