Publications by authors named "Claire Durrant"

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Confirmation of p-tau Ser356's association with Alzheimer's disease pathology and lowering in response to WZ4003 treatment in brain slice cultures. Reply to: "Phospho-tau Ser356 is mostly confined to pre-NFT neurons in Alzheimer's pathology".
Lewis W Taylor, Elizabeth M Simzer, Lauren F P Young, Kristján Holt, Tara L Spires-Jones, Claire S Durrant

Acta Neuropathol· December 2025

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Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy.
Robert I McGeachan, Lois Keavey, Elizabeth M Simzer, Ya Yin Chang, Jamie L Rose, Claire S Durrant

Nat Neurosci· August 2025

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Living and dying with Brenda Walker (and Motor Neurone Disease).
Brenda Walker, Claire Durrant, Kate Baker

Brain Neurosci Adv· July 2025

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Phylogenetic divergence of GABA receptor signaling in neocortical networks over adult life.
Max A Wilson, Anna Sumera, Lewis W Taylor, Soraya Meftah, Robert I McGeachan, Claire S Durrant

Nat Commun· May 2025

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Divergent actions of physiological and pathological amyloid-β on synapses in live human brain slice cultures.
Robert I McGeachan, Soraya Meftah, Lewis W Taylor, James H Catterson, Danilo Negro, Claire S Durrant

Nat Commun· April 2025

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appear resistant to trans-synaptic tau propagation.
James H Catterson, Edmond N Mouofo, Inés López De Toledo Soler, Gillian Lean, Stella Dlamini, Claire S Durrant

Brain Commun· August 2024

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Is amyloid-β a friend or foe?
Claire S Durrant

Nat Rev Mol Cell Biol· July 2024

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A nose for tau.
Soraya Meftah, Claire S Durrant, Tara L Spires-Jones

Sci Transl Med· July 2024

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Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease.
Martí Colom-Cadena, Jamie Toombs, Elizabeth Simzer, Kristjan Holt, Robert McGeachan, Claire S Durrant

Acta Neuropathol· February 2024

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p-tau Ser356 is associated with Alzheimer's disease pathology and is lowered in brain slice cultures using the NUAK inhibitor WZ4003.
Lewis W Taylor, Elizabeth M Simzer, Claire Pimblett, Oscar T T Lacey-Solymar, Robert I McGeachan, Claire S Durrant

Acta Neuropathol· January 2024

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Protein retention in the endoplasmic reticulum rescues Aβ toxicity in Drosophila.
James H Catterson, Lucy Minkley, Salomé Aspe, Sebastian Judd-Mole, Sofia Moura, Claire S Durrant

Neurobiol Aging· December 2023

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Alzheimer's disease-like neuropathology in three species of oceanic dolphin.
Marissa C Vacher, Claire S Durrant, Jamie Rose, Ailsa J Hall, Tara L Spires-Jones

Eur J Neurosci· April 2023

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Synaptic degeneration in Alzheimer disease.
Makis Tzioras, Robert I McGeachan, Claire S Durrant, Tara L Spires-Jones

Nat Rev Neurol· January 2023

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Preparation of Organotypic Hippocampal Slice Cultures for the Study of CNS Disease and Damage.
Claire S Durrant

Methods Mol Biol· March 2021

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Tau assemblies do not behave like independently acting prion-like particles in mouse neural tissue.
Lauren V C Miller, Aamir S Mukadam, Claire S Durrant, Marina J Vaysburd, Taxiarchis Katsinelos

Acta Neuropathol Commun· March 2021

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The physiological roles of tau and Aβ: implications for Alzheimer's disease pathology and therapeutics.
Sarah A Kent, Tara L Spires-Jones, Claire S Durrant

Acta Neuropathol· October 2020

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Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signalling.
Claire S Durrant, Karsten Ruscher, Olivia Sheppard, Michael P Coleman, Ilknur Özen

Cell Death Dis· February 2020

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Lipopolysaccharide-induced neuroinflammation induces presynaptic disruption through a direct action on brain tissue involving microglia-derived interleukin 1 beta.
Olivia Sheppard, Michael P Coleman, Claire S Durrant

J Neuroinflammation· May 2019

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Interaction between a MAPT variant causing frontotemporal dementia and mutant APP affects axonal transport.
Robert Adalbert, Stefan Milde, Claire Durrant, Kunie Ando, Virginie Stygelbout

Neurobiol Aging· August 2018

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