Publications by authors named "Clara Tang"

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Loss of function of Adducin 3 (ADD3) causes abnormal development and impaired barrier function of human and mouse bile duct cells resulting in increased incidence and severity of Biliary Atresia.
Jerry Lh Ha, Yongqin Ye, Hailong Liu, Zhongluan Wu, Amy Wy Wai, Clara Sm Tang

EBioMedicine· December 2025

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iRUNNER: A Baseline Mutation Burden Regression for Identifying Gene Interaction Between Rare Variants for Diseases.
Hui Jiang, Bin Tang, Kun Li, Liubin Zhang, Junhao Liang, Clara Sze-Man Tang

Genomics Proteomics Bioinformatics· December 2025

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Multi-ancestry genome-wide association meta-analysis identifies novel associations and informs genetic risk prediction for Hirschsprung disease.
Yuanxin Zhong, Man-Ting So, Zuyi Ma, Detao Zhang, Yanbing Wang, Clara Sze-Man Tang

EBioMedicine· May 2025

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Multifaceted analysis of noncoding and coding de novo variants implicates NOTCH signaling pathway in tetralogy of Fallot in Chinese population.
Qiongfen Lin, Detao Zhang, Peter J Gruber, Paul Kwong-Hang Tam, Vincent Chi-Hang Lui, Clara Sze-Man Tang

HGG Adv· April 2025

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Human Liver Organoids to Predict the Outcome of Kasai Portoenterostomy.
Amy Wing Yi Wai, Vincent Chi Hang Lui, Clara Sze Man Tang, Bin Wang, Paul Kwong Hang Tam

J Pediatr Surg· February 2025

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Genetics of biliary atresia: Approaches, pathological insights and challenges.
Qiongfen Lin, Paul Kwong-Hang Tam, Clara Sze-Man Tang

Semin Pediatr Surg· December 2024

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General and sex-specific effects of vitamin D against atrial fibrillation and young-onset ischemic stroke: a Mendelian randomization series.
Yap-Hang Chan, Jie V Zhao, C Mary Schooling, Shiu-Lun Au Yeung, Yuen-Kwun Wong, Clara S Tang

J Clin Biochem Nutr· November 2024

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GestaltMatcher Database - A global reference for facial phenotypic variability in rare human diseases.
Hellen Lesmann, Alexander Hustinx, Shahida Moosa, Hannah Klinkhammer, Elaine Marchi, Clara Tang

medRxiv· October 2024

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Animal and organoid models to elucidate the anti-fibrotic effect of steroid on biliary atresia.
Fangran Liu, Vincent Chi Hang Lui, Zhongluan Wu, Paul David Blakeley, Clara Sze Man Tang

Pediatr Surg Int· August 2024

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A narrative review of genes associated with liver fibrosis in biliary atresia.
Fangran Liu, Clara Sze Man Tang, Patrick Ho Yu Chung

Transl Pediatr· August 2024

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Biliary atresia.
Paul K H Tam, Rebecca G Wells, Clara S M Tang, Vincent C H Lui, Maria Hukkinen

Nat Rev Dis Primers· July 2024

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Genome-wide association study of BNT162b2 vaccine-related myocarditis identifies potential predisposing functional areas in Hong Kong adolescents.
Chun Hing She, Hing Wai Tsang, Xingtian Yang, Sabrina Sl Tsao, Clara Sm Tang

BMC Genom Data· June 2024

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GestaltMatcher Database - A global reference for facial phenotypic variability in rare human diseases.
Hellen Lesmann, Alexander Hustinx, Shahida Moosa, Hannah Klinkhammer, Elaine Marchi, Clara Tang

Res Sq· June 2024

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Evaluation of ready-to-use freezer stocks of a synthetic microbial community for maize root colonization.
J Jacob Parnell, Simina Vintila, Clara Tang, Maggie R Wagner, Manuel Kleiner

Microbiol Spectr· January 2024

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Assessing the safety of lipid-modifying medications among Chinese adolescents: a drug-target Mendelian randomization study.
Shan Luo, Hugh Simon Lam, Yap Hang Chan, Clara Sze Man Tang, Baoting He

BMC Med· October 2023

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Artificial intelligence-based approaches for the detection and prioritization of genomic mutations in congenital surgical diseases.
Qiongfen Lin, Paul Kwong-Hang Tam, Clara Sze-Man Tang

Front Pediatr· August 2023

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Genetics of Hirschsprung's disease.
Clara Sze-Man Tang, Anwarul Karim, Yuanxin Zhong, Patrick Ho-Yu Chung, Paul Kwong-Hang Tam

Pediatr Surg Int· February 2023

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Isogenic Human-Induced Pluripotent Stem-Cell-Derived Cardiomyocytes Reveal Activation of Wnt Signaling Pathways Underlying Intrinsic Cardiac Abnormalities in Rett Syndrome.
Kwong-Man Ng, Qianqian Ding, Yiu-Lam Tse, Oscar Hou-In Chou, Wing-Hon Lai, Clara Sze-Man Tang

Int J Mol Sci· December 2022

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Whole genome sequencing reveals epistasis effects within RET for Hirschsprung disease.
Yanbing Wang, Timothy Shin Heng Mak, Saloni Dattani, Maria-Merce Garcia-Barcelo, Alexander Xi Fu, Clara Sze-Man Tang

Sci Rep· November 2022

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NGS4THAL, a One-Stop Molecular Diagnosis and Carrier Screening Tool for Thalassemia and Other Hemoglobinopathies by Next-Generation Sequencing.
Yujie Cao, Shau-Yin Ha, Chi-Chiu So, Ming-For Tony Tong, Clara Sze-Man Tang

J Mol Diagn· October 2022

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A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study.
Xiangfeng Lu, Zhongying Liu, Qingmei Cui, Fangchao Liu, Jianxin Li, Clara Sze-Man Tang, Tangchun Wu

Eur Heart J· May 2022

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Differential vulnerability of hippocampal CA3-CA1 synapses to Aβ.
Olivia A Shipton, Clara S Tang, Ole Paulsen, Mariana Vargas-Caballero

Acta Neuropathol Commun· April 2022

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Current Understanding in the Clinical Characteristics and Molecular Mechanisms in Different Subtypes of Biliary Atresia.
Lin He, Patrick Ho Yu Chung, Vincent Chi Hang Lui, Clara Sze Man Tang, Paul Kwong Hang Tam

Int J Mol Sci· April 2022

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Comprehensive analysis of recessive carrier status using exome and genome sequencing data in 1543 Southern Chinese.
Jeffrey Fong Ting Chau, Mullin Ho Chung Yu, Martin Man Chun Chui, Cyrus Chun Wing Yeung, Aaron Wing Cheung Kwok, Clara Sze Man Tang

NPJ Genom Med· March 2022

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Mendelian randomization analysis of vitamin D in the secondary prevention of hypertensive-diabetic subjects: role of facilitating blood pressure control.
Yap-Hang Chan, C Mary Schooling, Jie V Zhao, Shiu-Lun Au Yeung, Jo Jo Hai, Clara S Tang

Genes Nutr· January 2022

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