Publications by authors named "Clare Jolly"

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Human guanylate-binding protein (GBP) 1 inhibits replication of severe acute respiratory syndrome coronavirus 2.
Rubaiyea Farrukee, Francesca Mordant, Charley Mackenzie-Kludas, Dejan Mesner, Masahiro Yamomoto, Clare Jolly

J Virol· October 2025

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Signatures of omicron-like adaptation in early SARS-CoV-2 variants and chronic infection.
Mark Tsz Kin Cheng, Mazharul Altaf, Jesu Castin, Ann-Kathrin Reuschl, Benjamin L Sievers, Clare Jolly

Cell Rep· August 2025

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HIV-1 Gag-protease-driven replicative capacity influences T-cell metabolism, cytokine induction, and viral cell-to-cell spread.
Omolara O Baiyegunhi, Kensane Mthembu, Ann-Kathrin Reuschl, Doty Ojwach, Omotayo Farinre, Clare Jolly

mBio· April 2025

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Macrocycle-based PROTACs selectively degrade cyclophilin A and inhibit HIV-1 and HCV.
Lydia S Newton, Clara Gathmann, Sophie Ridewood, Robert J Smith, Andre J Wijaya, Clare Jolly

Nat Commun· February 2025

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Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants.
Ann-Kathrin Reuschl, Lucy G Thorne, Matthew V X Whelan, Roberta Ragazzini, Wilhelm Furnon, Clare Jolly

Nat Microbiol· February 2024

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SARS-CoV-2 variants evolve convergent strategies to remodel the host response.
Mehdi Bouhaddou, Ann-Kathrin Reuschl, Benjamin J Polacco, Lucy G Thorne, Manisha R Ummadi, Clare Jolly

Cell· October 2023

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SARS-CoV-2 evolution influences GBP and IFITM sensitivity.
Dejan Mesner, Ann-Kathrin Reuschl, Matthew V X Whelan, Taylor Bronzovich, Tafhima Haider, Clare Jolly

Proc Natl Acad Sci U S A· January 2023

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Evolutionary remodelling of N-terminal domain loops fine-tunes SARS-CoV-2 spike.
Diego Cantoni, Matthew J Murray, Mphatso D Kalemera, Samuel J Dicken, Lenka Stejskal, Clare Jolly

EMBO Rep· October 2022

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Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19.
Jose F Varona, Pedro Landete, Jose A Lopez-Martin, Vicente Estrada, Roger Paredes, Clare Jolly

Life Sci Alliance· April 2022

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Publisher Correction: Evolution of enhanced innate immune evasion by SARS-CoV-2.
Lucy G Thorne, Mehdi Bouhaddou, Ann-Kathrin Reuschl, Lorena Zuliani-Alvarez, Ben Polacco, Clare Jolly

Nature· April 2022

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HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells.
Ann-Kathrin Reuschl, Dejan Mesner, Maitreyi Shivkumar, Matthew V X Whelan, Laura J Pallett, Clare Jolly

Cell Rep· April 2022

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Local and systemic responses to SARS-CoV-2 infection in children and adults.
Masahiro Yoshida, Kaylee B Worlock, Ni Huang, Rik G H Lindeboom, Colin R Butler, Clare Jolly

Nature· February 2022

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Evolution of enhanced innate immune evasion by SARS-CoV-2.
Lucy G Thorne, Mehdi Bouhaddou, Ann-Kathrin Reuschl, Lorena Zuliani-Alvarez, Ben Polacco, Clare Jolly

Nature· February 2022

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Executable network of SARS-CoV-2-host interaction predicts drug combination treatments.
Rowan Howell, Matthew A Clarke, Ann-Kathrin Reuschl, Tianyi Chen, Sean Abbott-Imboden, Clare Jolly

NPJ Digit Med· February 2022

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A Conserved Tryptophan in the Envelope Cytoplasmic Tail Regulates HIV-1 Assembly and Spread.
Xenia Snetkov, Tafhima Haider, Dejan Mesner, Nicholas Groves, Schuyler B van Engelenburg, Clare Jolly

Viruses· January 2022

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SARS-CoV-2 sensing by RIG-I and MDA5 links epithelial infection to macrophage inflammation.
Lucy G Thorne, Ann-Kathrin Reuschl, Lorena Zuliani-Alvarez, Matthew V X Whelan, Jane Turner, Clare Jolly

EMBO J· August 2021

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Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant.
Lucy G Thorne, Mehdi Bouhaddou, Ann-Kathrin Reuschl, Lorena Zuliani-Alvarez, Ben Polacco, Clare Jolly

bioRxiv· June 2021

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Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint.
Nathalie M Schmidt, Peter A C Wing, Mariana O Diniz, Laura J Pallett, Leo Swadling, Clare Jolly

Nat Commun· May 2021

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HIV envelope tail truncation confers resistance to SERINC5 restriction.
Tafhima Haider, Xenia Snetkov, Clare Jolly

Proc Natl Acad Sci U S A· May 2021

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Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization.
José F Varona, Pedro Landete, Jose A Lopez-Martin, Vicente Estrada, Roger Paredes, Clare Jolly

medRxiv· May 2021

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Characterisation of B.1.1.7 and Pangolin coronavirus spike provides insights on the evolutionary trajectory of SARS-CoV-2.
Samuel J Dicken, Matthew J Murray, Lucy G Thorne, Ann-Kathrin Reuschl, Calum Forrest, Clare Jolly

bioRxiv· March 2021

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Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant.
Ann-Kathrin Reuschl, Lucy G Thorne, Lorena Zuliani-Alvarez, Mehdi Bouhaddou, Kirsten Obernier, Clare Jolly

bioRxiv· February 2021

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Emergence of a Novel Protease Inhibitor Resistance Signature in HIV-1 Matrix.
Rawlings Datir, Steven Kemp, Kate El Bouzidi, Petra Mlchocova, Richard Goldstein, Clare Jolly

mBio· November 2020

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Loss of Nef-mediated CD3 down-regulation in the HIV-1 lineage increases viral infectivity and spread.
Dejan Mesner, Dominik Hotter, Frank Kirchhoff, Clare Jolly

Proc Natl Acad Sci U S A· March 2020

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Combination antiretroviral therapy and cell-cell spread of wild-type and drug-resistant human immunodeficiency virus-1.
Boghuma Kabisen Titanji, Deenan Pillay, Clare Jolly

J Gen Virol· April 2017

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