Publications by authors named "Claude Libert"

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Balancing metabolism and regeneration in liver diseases through HNF4α targeting.
Céline Van Dender, Jolien Vandewalle, Claude Libert

Trends Endocrinol Metab· January 2026

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CARD14 signaling in intestinal epithelial cells induces intestinal inflammation and intestinal transit delay.
Aigerim Aidarova, Marieke Carels, Mira Haegman, Yasmine Driege, Steven Timmermans, Claude Libert

EMBO Mol Med· December 2025

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Correction: Generation of a new Paneth cell-specific -recombinase transgenic mouse line.
Natalia Garcia-Gonzalez, Charlotte Wallaeys, Wendy Toussaint, Tino Hochepied, Sylviane Dewaele, Claude Libert

Front Immunol· December 2025

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A crucial role of the malate aspartate shuttle in metabolic reprogramming in TNF-induced SIRS.
Louise Nuyttens, Marah Heyerick, Maxime Roes, Elise Moens, Céline Van Dender, Claude Libert

Front Immunol· October 2025

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HNF4α contributes to hepatic CAR dysfunction in polymicrobial sepsis.
Céline Van Dender, Steven Timmermans, Maxime Roes, Madeleine Hellemans, Elise Moens, Claude Libert

Front Immunol· September 2025

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Unraveling mitochondrial pyruvate dysfunction to mitigate hyperlactatemia and lethality in sepsis.
Louise Nuyttens, Marah Heyerick, Geike Heremans, Elise Moens, Maxime Roes, Claude Libert

Cell Rep· August 2025

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Gradual DNA methylation changes reveal transcription factors implicated in metabolic dysfunction-associated steatotic liver disease progression and epigenetic age acceleration.
Evelien Van Dijck, Steven Van Laere, Emilie Logie, Steven Timmermans, Erik Fransen, Claude Libert

Clin Epigenetics· August 2025

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Modulation of glucocorticoid receptor function under iron overload.
Wanting Zhu, Tineke Vanderhaeghen, Steven Timmermans, Jolien Vandewalle, Melanie Eggermont, Claude Libert

Front Immunol· July 2025

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Generation of a new Paneth cell-specific -recombinase transgenic mouse line.
Natalia Garcia-Gonzalez, Charlotte Wallaeys, Wendy Toussaint, Tino Hochepied, Sylviane Dewaele, Claude Libert

Front Immunol· July 2025

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Detection of chimeric alpha-defensin transcripts and peptides in mouse Paneth cells.
Steven Timmermans, Charlotte Wallaeys, Somara De Beul, Natalia Garcia-Gonzales, Claude Libert

Front Immunol· May 2025

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Sepsis-induced changes in pyruvate metabolism: insights and potential therapeutic approaches.
Louise Nuyttens, Jolien Vandewalle, Claude Libert

EMBO Mol Med· November 2024

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Polo-like kinase 1 (PLK1) is a novel CARD14-binding protein in keratinocytes.
Styliani Iliaki, Marja Kreike, Natalia Ferreras Moreno, Femke De Meyer, Aigerim Aidarova, Claude Libert

Biochem Pharmacol· October 2024

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Paneth cell TNF signaling induces gut bacterial translocation and sepsis.
Charlotte Wallaeys, Natalia Garcia-Gonzalez, Steven Timmermans, Jolien Vandewalle, Tineke Vanderhaeghen, Claude Libert

Cell Host Microbe· October 2024

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A critical role for HNF4α in polymicrobial sepsis-associated metabolic reprogramming and death.
Céline Van Dender, Steven Timmermans, Ville Paakinaho, Tineke Vanderhaeghen, Jolien Vandewalle, Claude Libert

EMBO Mol Med· October 2024

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Comparative Analysis of Hepatic Gene Expression Profiles in Murine and Porcine Sepsis Models.
Fëllanza Halimi, Tineke Vanderhaeghen, Steven Timmermans, Siska Croubels, Claude Libert

Int J Mol Sci· October 2024

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Microbial metabolome in septic shock: Bridging bench to bedside.
Jolien Vandewalle, Claude Libert

Cell Host Microbe· August 2024

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Identification and Characterization of Multiple Paneth Cell Types in the Mouse Small Intestine.
Steven Timmermans, Charlotte Wallaeys, Natalia Garcia-Gonzalez, Lotte Pollaris, Yvan Saeys, Claude Libert

Cells· August 2024

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Crosstalk interactions between transcription factors ERRα and PPARα assist PPARα-mediated gene expression.
Sofie J Desmet, Jonathan Thommis, Tineke Vanderhaeghen, Edmee M F Vandenboorn, Dorien Clarisse, Claude Libert

Mol Metab· June 2024

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Immunomodulation by glucocorticoid-induced leucine zipper in macrophages: enhanced phagocytosis, protection from pyroptosis, and altered mitochondrial function.
Thierry M Legroux, Hanna S Schymik, Gilles Gasparoni, Saeed Mohammadi, Jörn Walter, Claude Libert

Front Immunol· June 2024

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MeCP2 binds to methylated DNA independently of phase separation and heterochromatin organisation.
Raphaël Pantier, Megan Brown, Sicheng Han, Katie Paton, Stephen Meek, Claude Libert

Nat Commun· May 2024

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Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in metabolic dysfunction associated Steatotic liver disease (MASLD).
Claudia Theys, Tineke Vanderhaeghen, Evelien Van Dijck, Cedric Peleman, Anne Scheepers, Claude Libert

Front Mol Med· January 2024

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Spns2/S1P: it takes two to tango with inflammation and metabolic rewiring during sepsis.
Tineke Vanderhaeghen, Jolien Vandewalle, Claude Libert

EMBO Rep· August 2023

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The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function.
Tineke Vanderhaeghen, Steven Timmermans, Melanie Eggermont, Deepika Watts, Jolien Vandewalle, Claude Libert

Front Immunol· April 2023

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Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF.
Kai Ling Liang, Juliette Roels, Marieke Lavaert, Tom Putteman, Lena Boehme, Claude Libert

Nat Immunol· March 2023

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Mousepost 2.0, a major expansion of the resource.
Steven Timmermans, Jolien Vandewalle, Claude Libert

Nucleic Acids Res· February 2023

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