Publications by authors named "Claudia Heuser"

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An IL12-IL2-antibody fusion protein targeting Hodgkin's lymphoma cells potentiates activation of NK and T cells for an anti-tumor attack.
Tobias Jahn, Martin Zuther, Björn Friedrichs, Claudia Heuser, Stefan Guhlke

PLoS One· March 2013

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T cell activation by antibody-like immunoreceptors: the position of the binding epitope within the target molecule determines the efficiency of activation of redirected T cells.
Andreas A Hombach, Verena Schildgen, Claudia Heuser, Ricarda Finnern, David E Gilham

J Immunol· April 2007

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Simultaneous targeting of IL2 and IL12 to Hodgkin's lymphoma cells enhances activation of resting NK cells and tumor cell lysis.
Andreas Hombach, Claudia Heuser, Hinrich Abken

Int J Cancer· June 2005

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T cell activation by antibody-like immunoreceptors: increase in affinity of the single-chain fragment domain above threshold does not increase T cell activation against antigen-positive target cells but decreases selectivity.
Markus Chmielewski, Andreas Hombach, Claudia Heuser, Gregory P Adams, Hinrich Abken

J Immunol· December 2004

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Anti-CD30-scFv-Fc-IL-2 antibody-cytokine fusion protein that induces resting NK cells to highly efficient cytolysis of Hodgkin's lymphoma derived tumour cells.
Claudia Heuser, Stefan Guhlke, Alexander Matthies, Hans Bender, Stefan Barth

Int J Cancer· June 2004

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Immune response manipulation: recombinant immunoreceptors endow T-cells with predefined specificity.
Hinrich Abken, Andreas Hombach, Claudia Heuser

Curr Pharm Des· December 2003

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Anti-CD30-IL-12 antibody-cytokine fusion protein that induces IFN-gamma secretion of T cells and NK cell-mediated lysis of Hodgkin's lymphoma-derived tumor cells.
Claudia Heuser, Volker Diehl, Hinrich Abken, Andreas Hombach

Int J Cancer· September 2003

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Generation, expression, and monitoring of recombinant immune receptors for use in cellular immunotherapy.
Andreas Hombach, Claudia Heuser, Hinrich Abken

Methods Mol Biol· May 2003

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Tuning tumor-specific T-cell activation: a matter of costimulation?
Hinrich Abken, Andreas Hombach, Claudia Heuser, Kai Kronfeld, Barbara Seliger

Trends Immunol· May 2002

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The recombinant T cell receptor strategy: insights into structure and function of recombinant immunoreceptors on the way towards an optimal receptor design for cellular immunotherapy.
Andreas Hombach, Claudia Heuser, Hinrich Abken

Curr Gene Ther· May 2002

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