Publications by authors named "Claudio Sorio"

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CFTR Modulator Response in Nasal Organoids Derived from People with Cystic Fibrosis.
Stefania Lo Cicero, Germana Castelli, Aurora Ceci, Anna Maria Cerio, Giovanna Blaconà, Claudio Sorio

Cells· December 2025

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Inflammation and epithelial-mesenchymal transition in a CFTR-depleted human bronchial epithelial cell line revealed by proteomics and human organ-on-a-chip.
Domenico Mattoscio, Luis A Baeza, Haiqing Bai, Tommaso Colangelo, Simone Castagnozzi, Claudio Sorio

FEBS J· October 2025

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Evaluation of the response to elexacaftor-tezacaftor-ivacaftor of the rare CFTR variants L383S, I507del, L1065P and R1066H in intestinal organoid-derived epithelial monolayers.
Jessica Conti, Dora Angyal, Karina Kleinfelder, Roberta Valeria Latorre, Martina Calicchia, Claudio Sorio

J Cyst Fibros· May 2025

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Corrigendum to "Evaluation of the response to elexacaftor-tezacaftor-ivacaftor of the rare CFTR variants L383S, I507del, L1065P and R1066H in intestinal organoid-derived epithelial monolayers" [Journal of Cystic Fibrosis xxx (2025) 1-10].
Jessica Conti, Dora Angyal, Karina Kleinfelder, Roberta Valeria Latorre, Martina Calicchia, Claudio Sorio

J Cyst Fibros· March 2025

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Adenine base editing with engineered virus-like particles rescues the mutation G542X in patient-derived intestinal organoids.
Lucia Nicosia, Iwona Pranke, Roberta V Latorre, Joss B Murray, Lisa Lonetti, Claudio Sorio

iScience· March 2025

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Elexacaftor/tezacaftor/ivacaftor in people with cystic fibrosis and rare mutations.
Valentina Fainardi, Federico Cresta, Claudio Sorio, Paola Melotti, Emanuela Pesce

Pediatr Pulmonol· December 2024

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Non pathological sweat test, pancreatic insufficiency and Cystic Fibrosis: an unusual case in a child with F508del-duplication of exons 1-3 CFTR genotype.
Vito Terlizzi, Cristina Fevola, Alice Castaldo, Selene Del Vespa, Daniela Dolce, Claudio Sorio

BMC Pediatr· November 2024

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Real-Life Experience with CFTR Modulators Shows Correction of LAD-IV Phenotype in Cystic Fibrosis.
Alessio Montresor, Beatrice D'Ulivo, Sara Preato, Alessia Farinazzo, Emily Pintani, Claudio Sorio

Am J Respir Cell Mol Biol· October 2024

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CFTR modulators response of S737F and T465N CFTR variants on patient-derived rectal organoids.
Karina Kleinfelder, Paola Melotti, Anca Manuela Hristodor, Cristina Fevola, Giovanni Taccetti, Claudio Sorio

Orphanet J Rare Dis· September 2024

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Loss of CFTR Reverses Senescence Hallmarks in SARS-CoV-2 Infected Bronchial Epithelial Cells.
Flavia Merigo, Anna Lagni, Federico Boschi, Paolo Bernardi, Anita Conti, Claudio Sorio

Int J Mol Sci· June 2024

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CFTR function is impaired in a subset of patients with pancreatitis carrying rare CFTR variants.
Dora Angyal, Karina Kleinfelder, Fabiana Ciciriello, Tessa A Groeneweg, Giulia De Marchi, Claudio Sorio

Pancreatology· May 2024

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Functional rescue of CFTR in rectal organoids from patients carrying R334W variant by CFTR modulators and PDE4 inhibitor Roflumilast.
Roberta Valeria Latorre, Martina Calicchia, Martina Bigliardi, Jessica Conti, Karina Kleinfelder, Claudio Sorio

Respir Investig· May 2024

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Management of chronic myeloid leukaemia: current treatment options, challenges, and future strategies.
Salma Younes, Mohamed A Ismail, Rana Al-Jurf, Ayah Ziyada, Gheyath K Nasrallah, Claudio Sorio

Hematology· December 2023

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analysis and theratyping of an ultra-rare CFTR genotype (W57G/A234D) in primary human rectal and nasal epithelial cells.
Karina Kleinfelder, Virginia Lotti, Adriana Eramo, Felice Amato, Stefania Lo Cicero, Claudio Sorio

iScience· November 2023

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How the latent geometry of a biological network provides information on its dynamics: the case of the gene network of chronic myeloid leukaemia.
Paola Lecca, Giulia Lombardi, Roberta Valeria Latorre, Claudio Sorio

Front Cell Dev Biol· November 2023

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Theratyping of the Rare CFTR Genotype A559T in Rectal Organoids and Nasal Cells Reveals a Relevant Response to Elexacaftor (VX-445) and Tezacaftor (VX-661) Combination.
Karina Kleinfelder, Valeria Rachela Villella, Anca Manuela Hristodor, Carlo Laudanna, Giuseppe Castaldo, Claudio Sorio

Int J Mol Sci· June 2023

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Crosslink between SARS-CoV-2 replication and cystic fibrosis hallmarks.
Virginia Lotti, Anna Lagni, Erica Diani, Claudio Sorio, Davide Gibellini

Front Microbiol· May 2023

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CFTR Modulators Rescue the Activity of CFTR in Colonoids Expressing the Complex Allele p.[R74W;V201M;D1270N]/dele22_24.
Karina Kleinfelder, Elena Somenza, Alessia Farinazzo, Jessica Conti, Virginia Lotti, Claudio Sorio

Int J Mol Sci· March 2023

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CFTR Inhibitors Display In Vitro Antiviral Activity against SARS-CoV-2.
Anna Lagni, Virginia Lotti, Erica Diani, Giada Rossini, Ercole Concia, Claudio Sorio

Cells· February 2023

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Organoid Technology and Its Role for Theratyping Applications in Cystic Fibrosis.
Jessica Conti, Claudio Sorio, Paola Melotti

Children (Basel)· December 2022

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Protein Tyrosine Phosphatase Receptor Gamma as Potential Therapeutic Target for Chronic Myeloid Leukemia Patients.
Mohamed A Ismail, Claudio Sorio, Nader Al-Dewik

Cancer Control· November 2022

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spp. Adaptation in Cystic Fibrosis Infection and Candidate Biomarkers of Antimicrobial Resistance.
Angela Sandri, Laura Veschetti, Giulia Maria Saitta, Rebeca Passarelli Mantovani, Maria Carelli, Claudio Sorio

Int J Mol Sci· August 2022

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Ultrastructural Characterization of Human Bronchial Epithelial Cells during SARS-CoV-2 Infection: Morphological Comparison of Wild-Type and CFTR-Modified Cells.
Flavia Merigo, Virginia Lotti, Paolo Bernardi, Anita Conti, Andrea Di Clemente, Claudio Sorio

Int J Mol Sci· August 2022

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Gene Expression Landscape of Chronic Myeloid Leukemia K562 Cells Overexpressing the Tumor Suppressor Gene PTPRG.
Giulia Lombardi, Roberta Valeria Latorre, Alessandro Mosca, Diego Calvanese, Luisa Tomasello, Claudio Sorio

Int J Mol Sci· August 2022

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Successful Preservation of Native BCR::ABL1 in Chronic Myeloid Leukemia Primary Leukocytes Reveals a Reduced Kinase Activity.
Christian Boni, Massimiliano Bonifacio, Marzia Vezzalini, Luigi Scaffidi, Luisa Tomasello, Claudio Sorio

Front Oncol· June 2022

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