Publications by authors named "Clay B Frederick"

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Reader comment on: "Comprehensive genotoxicity and carcinogenicity assessment of molnupiravir".
Clay B Frederick, Raymond F Schinazi, Ronald Swanstrom

Toxicol Sci· March 2025

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Native Oxyntomodulin Has Significant Glucoregulatory Effects Independent of Weight Loss in Obese Humans With and Without Type 2 Diabetes.
Sudha S Shankar, R Ravi Shankar, Lori A Mixson, Deborah L Miller, Barnali Pramanik, Clay B Frederick

Diabetes· June 2018

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Safety assessment of drug metabolites: implications of regulatory guidance and potential application of genetically engineered mouse models that express human P450s.
Mark W Powley, Clay B Frederick, Frank D Sistare, Joseph J DeGeorge

Chem Res Toxicol· February 2009

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CYP2C75-involved autoinduction of metabolism in rhesus monkeys of methyl 3-chloro-3'-fluoro-4'-{(1R)-1-[({1-[(trifluoroacetyl)amino]cyclopropyl}carbonyl)amino]ethyl}-1,1'-biphenyl-2-carboxylate (MK-0686), a bradykinin B1 receptor antagonist.
Cuyue Tang, Brian A Carr, Frédéric Poignant, Bennett Ma, Stacey L Polsky-Fisher, Clay B Frederick

J Pharmacol Exp Ther· June 2008

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Evaluation of ubiquinone concentration and mitochondrial function relative to cerivastatin-induced skeletal myopathy in rats.
William H Schaefer, Jeffery W Lawrence, Amy F Loughlin, Dana A Stoffregen, Lori A Mixson, Clay B Frederick

Toxicol Appl Pharmacol· January 2004

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Physiologically based pharmacokinetic (PBPK) models for nasal tissue dosimetry of organic esters: assessing the state-of-knowledge and risk assessment applications with methyl methacrylate and vinyl acetate.
Melvin E Andersen, Trevor Green, Clay B Frederick, Matthew S Bogdanffy

Regul Toxicol Pharmacol· December 2002

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Use of a hybrid computational fluid dynamics and physiologically based inhalation model for interspecies dosimetry comparisons of ester vapors.
Clay B Frederick, Larry G Lomax, Kurt A Black, Lavorgie Finch, Harvey E Scribner

Toxicol Appl Pharmacol· August 2002

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