Publications by authors named "Clement Douault"

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Optimisation of a novel series of potent and orally bioavailable azanaphthyridine SYK inhibitors.
Neil S Garton, Michael D Barker, Rob P Davis, Clement Douault, Edward Hooper-Greenhill

Bioorg Med Chem Lett· October 2016

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A Chemical Probe for the ATAD2 Bromodomain.
Paul Bamborough, Chun-Wa Chung, Emmanuel H Demont, Rebecca C Furze, Andrew J Bannister, Clement Douault

Angew Chem Int Ed Engl· September 2016

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Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives.
Susan M Westaway, Alex G S Preston, Michael D Barker, Fiona Brown, Jack A Brown, Clement Douault

J Med Chem· February 2016

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Structure-Based Optimization of Naphthyridones into Potent ATAD2 Bromodomain Inhibitors.
Paul Bamborough, Chun-wa Chung, Rebecca C Furze, Paola Grandi, Anne-Marie Michon, Clement Douault

J Med Chem· August 2015

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Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors.
Emmanuel H Demont, Chun-wa Chung, Rebecca C Furze, Paola Grandi, Anne-Marie Michon, Clement Douault

J Med Chem· July 2015

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Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor.
John Liddle, Francis L Atkinson, Michael D Barker, Paul S Carter, Neil R Curtis, Clement Douault

Bioorg Med Chem Lett· October 2011

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Pyrazolopyridazine alpha-2-delta-1 ligands for the treatment of neuropathic pain.
James W Myatt, Mark P Healy, Gianpaolo S Bravi, Andrew Billinton, Christopher N Johnson, Clement B Douault

Bioorg Med Chem Lett· August 2010

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