Publications by authors named "Codruta Ignea"

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Unraveling the regulatory dynamics of bidirectional promoters for modulating gene co-expression and metabolic flux in Saccharomyces cerevisiae.
Zimo Jin, Yueming Dong, Abdul Muntakim Rafi, Md Mohsin Patwary, Catherine Xu, Codruta Ignea

Nucleic Acids Res· June 2025

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Bioengineered yeast for preventing age-related diseases.
Olga Sofianovich, Kate Willis-Urena, Yueming Dong, Codruta Ignea

Trends Biotechnol· March 2025

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Synthetic biology advances towards a bio-based society in the era of artificial intelligence.
Attia Iram, Yueming Dong, Codruta Ignea

Curr Opin Biotechnol· June 2024

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Enhanced production of withaferin A from the hairy root culture of Withania somnifera via synergistic effect of Methyl jasmonate and β-cyclodextrin.
Mahbobeh Karami, Mohammad Reza Naghavi, Jaber Nasiri, Narjes Farzin, Codruta Ignea

Plant Physiol Biochem· March 2024

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Engineering yeast for the production of plant terpenoids using synthetic biology approaches.
Jean-Alexandre Bureau, Magdalena Escobar Oliva, Yueming Dong, Codruta Ignea

Nat Prod Rep· December 2023

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Widespread biosynthesis of 16-carbon terpenoids in bacteria.
Yao-Tao Duan, Aikaterini Koutsaviti, Maria Harizani, Codruta Ignea, Vassilios Roussis

Nat Chem Biol· December 2023

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Engineering membrane architecture for biotechnological applications.
Zimo Jin, Asia Vighi, Yueming Dong, Jean-Alexandre Bureau, Codruta Ignea

Biotechnol Adv· March 2023

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Expanding the terpene biosynthetic code with non-canonical 16 carbon atom building blocks.
Codruta Ignea, Morten H Raadam, Aikaterini Koutsaviti, Yong Zhao, Yao-Tao Duan

Nat Commun· September 2022

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Transforming yeast peroxisomes into microfactories for the efficient production of high-value isoprenoids.
Simon Dusséaux, William Thomas Wajn, Yixuan Liu, Codruta Ignea, Sotirios C Kampranis

Proc Natl Acad Sci U S A· December 2020

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Integrating pathway elucidation with yeast engineering to produce polpunonic acid the precursor of the anti-obesity agent celastrol.
Nikolaj L Hansen, Karel Miettinen, Yong Zhao, Codruta Ignea, Aggeliki Andreadelli

Microb Cell Fact· January 2020

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Orthogonal monoterpenoid biosynthesis in yeast constructed on an isomeric substrate.
Codruta Ignea, Morten H Raadam, Mohammed S Motawia, Antonios M Makris, Claudia E Vickers

Nat Commun· August 2019

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Isoprenoid biosynthesis in the diatom Haslea ostrearia.
Anastasia Athanasakoglou, Emilia Grypioti, Sofia Michailidou, Codruta Ignea, Antonios M Makris

New Phytol· April 2019

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Synthesis of 11-carbon terpenoids in yeast using protein and metabolic engineering.
Codruta Ignea, Marianna Pontini, Mohammed S Motawia, Massimo E Maffei, Antonios M Makris

Nat Chem Biol· December 2018

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Overcoming the plasticity of plant specialized metabolism for selective diterpene production in yeast.
Codruta Ignea, Anastasia Athanasakoglou, Aggeliki Andreadelli, Maria Apostolaki, Minas Iakovides

Sci Rep· August 2017

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Carnosic acid biosynthesis elucidated by a synthetic biology platform.
Codruta Ignea, Anastasia Athanasakoglou, Efstathia Ioannou, Panagiota Georgantea, Fotini A Trikka

Proc Natl Acad Sci U S A· March 2016

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Production of the forskolin precursor 11β-hydroxy-manoyl oxide in yeast using surrogate enzymatic activities.
Codruta Ignea, Efstathia Ioannou, Panagiota Georgantea, Fotini A Trikka, Anastasia Athanasakoglou

Microb Cell Fact· February 2016

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Combined metabolome and transcriptome profiling provides new insights into diterpene biosynthesis in S. pomifera glandular trichomes.
Fotini A Trikka, Alexandros Nikolaidis, Codruta Ignea, Aphrodite Tsaballa, Leto-Aikaterini Tziveleka

BMC Genomics· November 2015

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Use of the de novo transcriptome analysis of silver-leaf nightshade (Solanum elaeagnifolium) to identify gene expression changes associated with wounding and terpene biosynthesis.
Aphrodite Tsaballa, Alexandros Nikolaidis, Foteini Trikka, Codruta Ignea, Sotirios C Kampranis

BMC Genomics· July 2015

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Iterative carotenogenic screens identify combinations of yeast gene deletions that enhance sclareol production.
Fotini A Trikka, Alexandros Nikolaidis, Anastasia Athanasakoglou, Aggeliki Andreadelli, Codruta Ignea

Microb Cell Fact· April 2015

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Reconstructing the chemical diversity of labdane-type diterpene biosynthesis in yeast.
Codruta Ignea, Efstathia Ioannou, Panagiota Georgantea, Sofia Loupassaki, Fotini A Trikka

Metab Eng· March 2015

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Efficient diterpene production in yeast by engineering Erg20p into a geranylgeranyl diphosphate synthase.
Codruta Ignea, Fotini A Trikka, Alexandros K Nikolaidis, Panagiota Georgantea, Efstathia Ioannou

Metab Eng· January 2015

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The downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 axis and by human cytomegalovirus (HCMV) associated factors allows the activation of the HCMV major IE promoter and the transition to productive infection.
George Sourvinos, Antigoni Morou, Ioannis Sanidas, Ignea Codruta, Scott A Ezell

PLoS Pathog· May 2014

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Engineering monoterpene production in yeast using a synthetic dominant negative geranyl diphosphate synthase.
Codruta Ignea, Marianna Pontini, Massimo E Maffei, Antonios M Makris, Sotirios C Kampranis

ACS Synth Biol· May 2014

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Modulation of the antioxidant/pro-oxidant balance, cytotoxicity and antiviral actions of grape seed extracts.
Codruţa Ignea, Cristina Mihaela Dorobanţu, Christopher Paul Mintoff, Norica Branza-Nichita, Michael R Ladomery

Food Chem· December 2013

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Positive genetic interactors of HMG2 identify a new set of genetic perturbations for improving sesquiterpene production in Saccharomyces cerevisiae.
Codruta Ignea, Fotini A Trikka, Ioannis Kourtzelis, Anagnostis Argiriou, Angelos K Kanellis

Microb Cell Fact· December 2012

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