Publications by authors named "Colin A Flaveny"

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A two-hit model of alcoholic liver disease that exhibits rapid, severe fibrosis.
Monideepa Sengupta, Suomia Abuirqeba, Amina Kameric, Aurore Cecile-Valfort, Arindam Chatterjee, Colin A Flaveny

PLoS One· July 2024

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Combined regenerative rehabilitation improves recovery following volumetric muscle loss injury in a rat model.
David Johnson, Connor Tobo, Jeffrey Au, Aakash Nagarapu, Natalia Ziemkiewicz, Colin A Flaveny

J Biomed Mater Res B Appl Biomater· July 2024

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International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily-Update 2023.
Thomas P Burris, Ian Mitchelle S de Vera, Isabelle Cote, Colin A Flaveny, Udayanga S Wanninayake

Pharmacol Rev· November 2023

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Retinal Degeneration: Short-Term Options and Long-Term Vision for Future Therapy.
Shabnam Majidi, Judith M Ogilvie, Colin A Flaveny

Mo Med· October 2021

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CRTC1/MAML2 directs a PGC-1α-IGF-1 circuit that confers vulnerability to PPARγ inhibition.
Adele M Musicant, Kshitij Parag-Sharma, Weida Gong, Monideepa Sengupta, Arindam Chatterjee, Colin A Flaveny

Cell Rep· February 2021

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Rev-erbα heterozygosity produces a dose-dependent phenotypic advantage in mice.
Ryan D Welch, Cyrielle Billon, Amina Kameric, Thomas P Burris, Colin A Flaveny

PLoS One· July 2020

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LXR-inverse agonism stimulates immune-mediated tumor destruction by enhancing CD8 T-cell activity in triple negative breast cancer.
Katherine J Carpenter, Aurore-Cecile Valfort, Nick Steinauer, Arindam Chatterjee, Suomia Abuirqeba, Colin A Flaveny

Sci Rep· December 2019

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Inhibition of Hepatotoxicity by a LXR Inverse Agonist in a Model of Alcoholic Liver Disease.
Monideepa Sengupta, Kristine Griffett, Colin A Flaveny, Thomas P Burris

ACS Pharmacol Transl Sci· September 2018

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Pharmacological inhibition of REV-ERB stimulates differentiation, inhibits turnover and reduces fibrosis in dystrophic muscle.
Ryan D Welch, Cyrielle Billon, Aurore-Cecile Valfort, Thomas P Burris, Colin A Flaveny

Sci Rep· December 2017

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Rev-Erb co-regulates muscle regeneration via tethered interaction with the NF-Y cistrome.
Ryan D Welch, Chun Guo, Monideepa Sengupta, Katherine J Carpenter, Natalie A Stephens, Colin A Flaveny

Mol Metab· July 2017

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REV-ERB and ROR: therapeutic targets for treating myopathies.
Ryan D Welch, Colin A Flaveny

Phys Biol· June 2017

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Fluorophore-NanoLuc BRET Reporters Enable Sensitive In Vivo Optical Imaging and Flow Cytometry for Monitoring Tumorigenesis.
Franz X Schaub, Md Shamim Reza, Colin A Flaveny, Weimin Li, Adele M Musicant

Cancer Res· December 2015

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Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis.
Bin Li, Colin A Flaveny, Camilla Giambelli, Dennis Liang Fei, Lu Han

PLoS One· October 2015

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Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis.
Colin A Flaveny, Kristine Griffett, Bahaa El-Dien M El-Gendy, Melissa Kazantzis, Monideepa Sengupta

Cancer Cell· July 2015

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The LXR inverse agonist SR9238 suppresses fibrosis in a model of non-alcoholic steatohepatitis.
Kristine Griffett, Ryan D Welch, Colin A Flaveny, Grant R Kolar, Brent A Neuschwander-Tetri

Mol Metab· April 2015

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Pyrvinium attenuates Hedgehog signaling downstream of smoothened.
Bin Li, Dennis Liang Fei, Colin A Flaveny, Nadia Dahmane, Valérie Baubet

Cancer Res· September 2014

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Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3',4'-dimethoxy-α-naphthoflavone.
Iain A Murray, Colin A Flaveny, Christopher R Chiaro, Arun K Sharma, Rachel S Tanos

Mol Pharmacol· March 2011

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Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells.
Anthony E Boitano, Jian Wang, Russell Romeo, Laure C Bouchez, Albert E Parker, Colin A Flaveny

Science· September 2010

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Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling.
Brett C DiNatale, Iain A Murray, Jennifer C Schroeder, Colin A Flaveny, Tejas S Lahoti

Toxicol Sci· May 2010

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Differential gene regulation by the human and mouse aryl hydrocarbon receptor.
Colin A Flaveny, Iain A Murray, Gary H Perdew

Toxicol Sci· April 2010

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Evidence for ligand-mediated selective modulation of aryl hydrocarbon receptor activity.
Iain A Murray, Jose L Morales, Colin A Flaveny, Brett C Dinatale, Chris Chiaro

Mol Pharmacol· February 2010

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Antagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimethoxyflavone.
Iain A Murray, Colin A Flaveny, Brett C DiNatale, Chris R Chairo, Jennifer C Schroeder

J Pharmacol Exp Ther· January 2010

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The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor.
Jennifer C Schroeder, Brett C Dinatale, Iain A Murray, Colin A Flaveny, Qiang Liu

Biochemistry· January 2010

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Ligand selectivity and gene regulation by the human aryl hydrocarbon receptor in transgenic mice.
Colin A Flaveny, Iain A Murray, Chris R Chiaro, Gary H Perdew

Mol Pharmacol· June 2009

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Ah receptor represses acute-phase response gene expression without binding to its cognate response element.
Rushang D Patel, Iain A Murray, Colin A Flaveny, Ann Kusnadi, Gary H Perdew

Lab Invest· June 2009

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