Publications by authors named "Colin A Holbrook"

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Multiomic profiling reveals that prostaglandin E2 reverses aged muscle stem cell dysfunction, leading to increased regeneration and strength.
Yu Xin Wang, Adelaida R Palla, Andrew T V Ho, Daniel C L Robinson, Meenakshi Ravichandran, Colin A Holbrook

Cell Stem Cell· July 2025

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Hydrogel biomaterials that stiffen and soften on demand reveal that skeletal muscle stem cells harbor a mechanical memory.
Christopher M Madl, Yu Xin Wang, Colin A Holbrook, Shiqi Su, Xuechen Shi

Proc Natl Acad Sci U S A· August 2024

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Machine learning-based classification of dual fluorescence signals reveals muscle stem cell fate transitions in response to regenerative niche factors.
Matteo Togninalli, Andrew T V Ho, Christopher M Madl, Colin A Holbrook, Yu Xin Wang

NPJ Regen Med· January 2023

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Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration.
Ermelinda Porpiglia, Thach Mai, Peggy Kraft, Colin A Holbrook, Antoine de Morree

Cell Stem Cell· December 2022

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Biophysical matrix cues from the regenerating niche direct muscle stem cell fate in engineered microenvironments.
Christopher M Madl, Iris A Flaig, Colin A Holbrook, Yu Xin Wang, Helen M Blau

Biomaterials· August 2021

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Prostaglandin E2 is essential for efficacious skeletal muscle stem-cell function, augmenting regeneration and strength.
Andrew T V Ho, Adelaida R Palla, Matthew R Blake, Nora D Yucel, Yu Xin Wang, Colin A Holbrook

Proc Natl Acad Sci U S A· June 2017

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