Publications by authors named "Colin D Medley"

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Automated online deconjugation of antibody-drug conjugate for small molecule drug profiling.
Rekha Thomas, Dong Song, Tony Pourmohamad, Kenji Kurita, Steven Chin, Colin D Medley

J Chromatogr A· January 2024

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A Small-scale Model to Assess the Risk of Leachables from Single-use Bioprocess Containers through Protein Quality Characterization.
Nina J Xiao, Colin D Medley, Ian C Shieh, Gregory Downing, Shelly Pizarro

PDA J Pharm Sci Technol· May 2018

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An enzymatic deconjugation method for the analysis of small molecule active drugs on antibody-drug conjugates.
Yi Li, Christine Gu, Jason Gruenhagen, Peter Yehl, Nik P Chetwyn, Colin D Medley

MAbs· November 2017

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Investigation of low recovery in the free drug assay for antibody drug conjugates by size exclusion-reversed phase two dimensional-liquid chromatography.
Yi Li, Cinzia Stella, Laura Zheng, Charity Bechtel, Jason Gruenhagen, Colin D Medley

J Chromatogr B Analyt Technol Biomed Life Sci· October 2016

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Antibody-drug conjugate characterization by chromatographic and electrophoretic techniques.
Tao Chen, Yan Chen, Cinzia Stella, Colin D Medley, Jason A Gruenhagen

J Chromatogr B Analyt Technol Biomed Life Sci· October 2016

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Chemical de-conjugation for investigating the stability of small molecule drugs in antibody-drug conjugates.
Tao Chen, Dian Su, Jason Gruenhagen, Christine Gu, Yi Li, Colin D Medley

J Pharm Biomed Anal· January 2016

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A size exclusion-reversed phase two dimensional-liquid chromatography methodology for stability and small molecule related species in antibody drug conjugates.
Yi Li, Christine Gu, Jason Gruenhagen, Kelly Zhang, Peter Yehl, Colin D Medley

J Chromatogr A· May 2015

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Quantification of residual solvents in antibody drug conjugates using gas chromatography.
Colin D Medley, Jacob Kay, Yi Li, Jason Gruenhagen, Peter Yehl

Anal Chim Acta· November 2014

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Limiting degradation of reactive antibody drug conjugate intermediates in HPLC method development.
Yi Li, Colin D Medley, Kelly Zhang, Larry Wigman, Nik Chetwyn

J Pharm Biomed Anal· April 2014

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Turning on lanthanide luminescence via nanoencapsulation.
Boris Makhinson, Alexandra K Duncan, Ashley R Elam, Ana de Bettencourt-Dias, Colin D Medley

Inorg Chem· June 2013

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A DNA-conjugated magnetic nanoparticle assay for assessing genotoxicity.
Colin D Medley, Joshua E Smith, Larry S Wigman, Nik P Chetwyn

Anal Bioanal Chem· November 2012

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Aptamer-conjugated nanoparticles for cancer cell detection.
Colin D Medley, Suwussa Bamrungsap, Weihong Tan, Joshua E Smith

Anal Chem· February 2011

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Quantitation of plasmid DNA deposited on gold particles for particle-mediated epidermal delivery using ICP-MS.
Colin D Medley, Bilikallahalli K Muralidhara, Steven Chico, Stephen Durban, Paul Mehelic

Anal Bioanal Chem· September 2010

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Locked nucleic acid based beacons for surface interaction studies and biosensor development.
Karen Martinez, M-Carmen Estevez, Yanrong Wu, Joseph A Phillips, Colin D Medley

Anal Chem· May 2009

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Molecular engineering of DNA: molecular beacons.
Kemin Wang, Zhiwen Tang, Chaoyong James Yang, Youngmi Kim, Xiaohong Fang, Colin D Medley

Angew Chem Int Ed Engl· February 2009

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Molecular recognition of small-cell lung cancer cells using aptamers.
Hui William Chen, Colin D Medley, Kwame Sefah, Dihua Shangguan, Zhiwen Tang

ChemMedChem· June 2008

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Investigation of the hybrid molecular probe for intracellular studies.
Karen Martinez, Colin D Medley, Chaoyong James Yang, Weihong Tan

Anal Bioanal Chem· June 2008

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Antibody-functionalized nano test tubes target breast cancer cells.
Fatih Buyukserin, Colin D Medley, Miguel O Mota, Kaan Kececi, Richard R Rogers

Nanomedicine (Lond)· June 2008

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Gold nanoparticle-based colorimetric assay for the direct detection of cancerous cells.
Colin D Medley, Joshua E Smith, Zhiwen Tang, Yanrong Wu, Suwussa Bamrungsap

Anal Chem· February 2008

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Separation and detection of individual submicron particles by capillary electrophoresis with laser-light-scattering detection.
Yohannes H Rezenom, Amber D Wellman, Luanne Tilstra, Colin D Medley, S Douglass Gilman

Analyst· December 2007

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Multiplexed detection of ions and mRNA expression in single living cells.
Colin D Medley, Hui Lin, Hillary Mullins, Richard J Rogers, Weihong Tan

Analyst· September 2007

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Synthesis and investigation of deoxyribonucleic acid/locked nucleic acid chimeric molecular beacons.
Chaoyong James Yang, Lin Wang, Yanrong Wu, Youngmi Kim, Colin D Medley

Nucleic Acids Res· August 2007

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Aptamer-conjugated nanoparticles for the collection and detection of multiple cancer cells.
Joshua E Smith, Colin D Medley, Zhiwen Tang, Dihua Shangguan, Charles Lofton

Anal Chem· April 2007

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Aptamer-conjugated nanoparticles for selective collection and detection of cancer cells.
Joshua K Herr, Joshua E Smith, Colin D Medley, Dihua Shangguan, Weihong Tan

Anal Chem· May 2006

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Monitoring nucleic acids using molecular beacons.
Chaoyong James Yang, Colin D Medley, Weihong Tan

Curr Pharm Biotechnol· December 2005

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