Publications by authors named "Colin J Meyer"

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Correction: Triterpenoid Dihydro-CDDO-Trifluoroethyl Amide Protects against Maladaptive Cardiac Remodeling and Dysfunction in Mice: A Critical Role of Nrf2.
Yifan Xing, Ting Niu, Wenjuan Wang, Jinqing Li, Siying Li, Colin J Meyer

PLoS One· November 2024

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Efficacy of Omaveloxolone in Friedreich's Ataxia: Delayed-Start Analysis of the MOXIe Extension.
David R Lynch, Melanie P Chin, Sylvia Boesch, Martin B Delatycki, Paola Giunti, Colin J Meyer

Mov Disord· February 2023

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Effects of Bardoxolone Methyl in Alport Syndrome.
Bradley A Warady, Pablo E Pergola, Rajiv Agarwal, Sharon Andreoli, Gerald B Appel, Colin J Meyer

Clin J Am Soc Nephrol· December 2022

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Study Design and Baseline Characteristics of the CARDINAL Trial: A Phase 3 Study of Bardoxolone Methyl in Patients with Alport Syndrome.
Glenn M Chertow, Gerald B Appel, Sharon Andreoli, Sripal Bangalore, Geoffrey A Block, Colin J Meyer

Am J Nephrol· January 2022

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Effects of Bardoxolone Methyl on Hepatic Enzymes in Patients with Type 2 Diabetes Mellitus and Stage 4 CKD.
James H Lewis, Michel Jadoul, Geoffrey A Block, Melanie P Chin, Deborah A Ferguson, Colin J Meyer

Clin Transl Sci· January 2021

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Understanding the role of the cytoprotective transcription factor nuclear factor erythroid 2-related factor 2-lessons from evolution, the animal kingdom and rare progeroid syndromes.
Peter Stenvinkel, Colin J Meyer, Geoffrey A Block, Glenn M Chertow, Paul G Shiels

Nephrol Dial Transplant· December 2020

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Effects of Bardoxolone Methyl on QT Interval in Healthy Volunteers.
Melanie P Chin, Shannon Rich, Angie Goldsberry, Megan O Apos Grady, Colin J Meyer

Cardiorenal Med· May 2020

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Effects of Bardoxolone Methyl on Magnesium in Patients with Type 2 Diabetes Mellitus and Chronic Kidney Disease.
Dana V Rizk, Arnold L Silva, Pablo E Pergola, Robert Toto, David G Warnock, Colin J Meyer

Cardiorenal Med· May 2020

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Bardoxolone methyl analog attenuates proteinuria-induced tubular damage by modulating mitochondrial function.
Hajime Nagasu, Yuji Sogawa, Kengo Kidokoro, Seiji Itano, Toshiya Yamamoto, Colin J Meyer

FASEB J· November 2019

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Effect of bardoxolone methyl on the urine albumin-to-creatinine ratio in patients with type 2 diabetes and stage 4 chronic kidney disease.
Peter Rossing, Geoffrey A Block, Melanie P Chin, Angie Goldsberry, Hiddo J L Heerspink, Colin J Meyer

Kidney Int· October 2019

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Orphan Drugs In Development For The Treatment Of Friedreich's Ataxia: Focus On Omaveloxolone.
Shaila D Ghanekar, Wai Wai Miller, Colin J Meyer, Kevin J Fenelon, Alvin Lacdao

Degener Neurol Neuromuscul Dis· October 2019

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Bardoxolone Methyl Improves Kidney Function in Patients with Chronic Kidney Disease Stage 4 and Type 2 Diabetes: Post-Hoc Analyses from Bardoxolone Methyl Evaluation in Patients with Chronic Kidney Disease and Type 2 Diabetes Study.
Melanie P Chin, George L Bakris, Geoffrey A Block, Glenn M Chertow, Angie Goldsberry, Colin J Meyer

Am J Nephrol· August 2019

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Effects of bardoxolone methyl on body weight, waist circumference and glycemic control in obese patients with type 2 diabetes mellitus and stage 4 chronic kidney disease.
Glenn M Chertow, Gerald B Appel, Geoffrey A Block, Melanie P Chin, Daniel W Coyne, Colin J Meyer

J Diabetes Complications· December 2018

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Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors.
Ben C Creelan, Dmitry I Gabrilovich, Jhanelle E Gray, Charles C Williams, Tawee Tanvetyanon, Colin J Meyer

Onco Targets Ther· August 2017

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A potent Nrf2 activator, dh404, bolsters antioxidant capacity in glial cells and attenuates ischaemic retinopathy.
Devy Deliyanti, Jae Young Lee, Steven Petratos, Colin J Meyer, Keith W Ward

Clin Sci (Lond)· August 2016

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Peloruside A Inhibits Growth of Human Lung and Breast Tumor Xenografts in an Athymic nu/nu Mouse Model.
Colin J Meyer, Melissa Krauth, Michael J Wick, Jerry W Shay, Ginelle Gellert

Mol Cancer Ther· August 2015

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The spatiotemporal regulation of the Keap1-Nrf2 pathway and its importance in cellular bioenergetics.
Albena T Dinkova-Kostova, Liam Baird, Kira M Holmström, Colin J Meyer, Andrey Y Abramov

Biochem Soc Trans· August 2015

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Topical application of RTA 408 lotion activates Nrf2 in human skin and is well-tolerated by healthy human volunteers.
Scott A Reisman, Angela R Goldsberry, Chun-Yue I Lee, Megan L O'Grady, Joel W Proksch, Colin J Meyer

BMC Dermatol· July 2015

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Mechanisms contributing to adverse cardiovascular events in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease treated with bardoxolone methyl.
Melanie P Chin, Scott A Reisman, George L Bakris, Megan O'Grady, Peter G Linde, Colin J Meyer

Am J Nephrol· March 2015

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Reply: To PMID 25307295.
Melanie P Chin, Colin J Meyer

J Card Fail· March 2015

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Risk factors for heart failure in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease treated with bardoxolone methyl.
Melanie P Chin, Danielle Wrolstad, George L Bakris, Glenn M Chertow, Dick de Zeeuw, Colin J Meyer

J Card Fail· December 2014

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A food effect study and dose proportionality study to assess the pharmacokinetics and safety of bardoxolone methyl in healthy volunteers.
Nathan S Teuscher, Richard J Kelley, Emily O Dumas, Cheri Enders Klein, Walid M Awni, Colin J Meyer

Clin Pharmacol Drug Dev· July 2014

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Targeting Nrf2 by dihydro-CDDO-trifluoroethyl amide enhances autophagic clearance and viability of β-cells in a setting of oxidative stress.
Wenjuan Li, Weiwei Wu, Haibo Song, Fang Wang, Huanjie Li, Colin J Meyer

FEBS Lett· June 2014

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Topical application of the synthetic triterpenoid RTA 408 protects mice from radiation-induced dermatitis.
Scott A Reisman, Chun-Yue I Lee, Colin J Meyer, Joel W Proksch, Stephen T Sonis

Radiat Res· May 2014

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