Publications by authors named "Colin Jaques"

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Manipulation of mRNA translation elongation influences the fragmentation of a biotherapeutic Fc-fusion protein produced in CHO cells.
Tanya J Knight, Jane F Povey, Davide Vito, Atul Mohindra, Colin M Jaques

Biotechnol Bioeng· December 2022

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A proline metabolism selection system and its application to the engineering of lipid biosynthesis in Chinese hamster ovary cells.
James D Budge, Joanne Roobol, Gurdeep Singh, Théo Mozzanino, Tanya J Knight, Colin M Jaques

Metab Eng Commun· December 2021

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Selection of CHO host and recombinant cell pools by inhibition of the proteasome results in enhanced product yields and cell specific productivity.
Tanya J Knight, Sarah Turner, Colin M Jaques, C Mark Smales

J Biotechnol· August 2021

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Feedback control of two supplemental feeds during fed-batch culture on a platform process using inline Raman models for glucose and phenylalanine concentration.
Thaddaeus A Webster, Brian C Hadley, Marissa Dickson, John K Busa, Colin Jaques

Bioprocess Biosyst Eng· January 2021

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Data for engineering lipid metabolism of Chinese hamster ovary (CHO) cells for enhanced recombinant protein production.
James D Budge, Tanya J Knight, Jane Povey, Joanne Roobol, Ian R Brown, Colin M Jaques

Data Brief· April 2020

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Engineering of Chinese hamster ovary cell lipid metabolism results in an expanded ER and enhanced recombinant biotherapeutic protein production.
James D Budge, Tanya J Knight, Jane Povey, Joanne Roobol, Ian R Brown, Colin M Jaques

Metab Eng· January 2020

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Improving the accuracy of flux balance analysis through the implementation of carbon availability constraints for intracellular reactions.
Maximilian Lularevic, Andrew J Racher, Colin Jaques, Alexandros Kiparissides

Biotechnol Bioeng· September 2019

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At-line raman spectroscopy and design of experiments for robust monitoring and control of miniature bioreactor cultures.
Ruth C Rowland-Jones, Colin Jaques

Biotechnol Prog· March 2019

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Development of generic raman models for a GS-KO CHO platform process.
Thaddaeus A Webster, Brian C Hadley, William Hilliard, Colin Jaques, Carrie Mason

Biotechnol Prog· May 2018

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Extraction of indirectly captured information for use in a comparison of offline pH measurement technologies.
Elspeth K Ritchie, Elaine B Martin, Andy Racher, Colin Jaques

J Biotechnol· June 2017

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Comparison of spectroscopy technologies for improved monitoring of cell culture processes in miniature bioreactors.
Ruth C Rowland-Jones, Frans van den Berg, Andrew J Racher, Elaine B Martin, Colin Jaques

Biotechnol Prog· March 2017

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