Publications by authors named "Colin M Fadzen"

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Rapid synthesis of glycosylated insulins by flow-based peptide synthesis.
Yuta Maki, Surin K Mong, Chaitra Chandrashekar, Briony E Forbes, Mohammed Akhter Hossain, Colin M Fadzen

Chem Sci· May 2025

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A Tumor-Homing Peptide Platform Enhances Drug Solubility, Improves Blood-Brain Barrier Permeability and Targets Glioblastoma.
Choi-Fong Cho, Charlotte E Farquhar, Colin M Fadzen, Benjamin Scott, Pei Zhuang

Cancers (Basel)· April 2022

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Deep learning to design nuclear-targeting abiotic miniproteins.
Carly K Schissel, Somesh Mohapatra, Justin M Wolfe, Colin M Fadzen, Kamela Bellovoda

Nat Chem· October 2021

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CT and MRI features differentiating mucinous cystic neoplasms of the liver from pathologically simple cysts.
Mark A Anderson, Ranjodh S Dhami, Colin M Fadzen, George Molina, Martin S Taylor

Clin Imaging· August 2021

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Targeting glioblastoma using a novel peptide specific to a deglycosylated isoform of brevican.
Niklas von Spreckelsen, Colin M Fadzen, Nina Hartrampf, Yarah Ghotmi, Justin M Wolfe

Adv Ther (Weinh)· April 2021

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A Platinum(IV) Prodrug-Perfluoroaryl Macrocyclic Peptide Conjugate Enhances Platinum Uptake in the Brain.
Colin M Fadzen, Justin M Wolfe, Wen Zhou, Choi-Fong Cho, Niklas von Spreckelsen

J Med Chem· July 2020

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Chimeras of Cell-Penetrating Peptides Demonstrate Synergistic Improvement in Antisense Efficacy.
Colin M Fadzen, Rebecca L Holden, Justin M Wolfe, Zi-Ning Choo, Carly K Schissel

Biochemistry· September 2019

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A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins.
Daniel T Cohen, Chi Zhang, Colin M Fadzen, Alexander J Mijalis, Liana Hie

Nat Chem· January 2019

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Blood-brain-barrier organoids for investigating the permeability of CNS therapeutics.
Sonja Bergmann, Sean E Lawler, Yuan Qu, Colin M Fadzen, Justin M Wolfe

Nat Protoc· December 2018

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Perfluoroaryl Bicyclic Cell-Penetrating Peptides for Delivery of Antisense Oligonucleotides.
Justin M Wolfe, Colin M Fadzen, Rebecca L Holden, Monica Yao, Gunnar J Hanson

Angew Chem Int Ed Engl· April 2018

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Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery.
Justin M Wolfe, Colin M Fadzen, Zi-Ning Choo, Rebecca L Holden, Monica Yao

ACS Cent Sci· April 2018

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Perfluoroarene-Based Peptide Macrocycles to Enhance Penetration Across the Blood-Brain Barrier.
Colin M Fadzen, Justin M Wolfe, Choi-Fong Cho, E Antonio Chiocca, Sean E Lawler

J Am Chem Soc· November 2017

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Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents.
Choi-Fong Cho, Justin M Wolfe, Colin M Fadzen, David Calligaris, Kalvis Hornburg

Nat Commun· June 2017

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Labeling proteins with fluorophore/thioamide Förster resonant energy transfer pairs by combining unnatural amino acid mutagenesis and native chemical ligation.
Rebecca F Wissner, Solongo Batjargal, Colin M Fadzen, E James Petersson

J Am Chem Soc· May 2013

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