Publications by authors named "Colin R Green"

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Retinal Hyperreflective Foci Are Biomarkers of Ocular Disease: A Scoping Review With Evidence From Humans and Insights From Animal Models.
Mohd N Mat Nor, Colin R Green, David Squirrell, Monica L Acosta

J Ophthalmol· May 2025

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Correlative light and X-ray tomography jointly unveil the critical role of connexin43 channels on inflammation-induced cellular ultrastructural alterations.
Chidinma Adanna Okolo, Jack Jonathan Maran, Amy Watts, Jaime Maripillan, Maria Harkiolaki, Colin R Green

Heliyon· April 2024

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Tonabersat Significantly Reduces Disease Progression in an Experimental Mouse Model of Multiple Sclerosis.
Andrea Kwakowsky, Bhavya Chawdhary, Antonio de Souza, Emily Meyer, Andrew H Kaye, Colin R Green

Int J Mol Sci· December 2023

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Hyper-reflective dots in optical coherence tomography imaging and inflammation markers in diabetic retinopathy.
Mohd N Mat Nor, Cindy X Guo, Colin R Green, David Squirrell, Monica L Acosta

J Anat· October 2023

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The central role of the NLRP3 inflammasome pathway in the pathogenesis of age-related diseases in the eye and the brain.
Jack J Maran, Moradeke M Adesina, Colin R Green, Andrea Kwakowsky, Odunayo O Mugisho

Ageing Res Rev· July 2023

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Retinal inner nuclear layer thickness in the diagnosis of cognitive impairment explored using a C57BL/6J mouse model.
Jack J Maran, Moradeke M Adesina, Colin R Green, Andrea Kwakowsky, Odunayo O Mugisho

Sci Rep· May 2023

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Orally Delivered Connexin43 Hemichannel Blocker, Tonabersat, Inhibits Vascular Breakdown and Inflammasome Activation in a Mouse Model of Diabetic Retinopathy.
Odunayo O Mugisho, Jyoti Aryal, Avik Shome, Heather Lyon, Monica L Acosta, Colin R Green

Int J Mol Sci· February 2023

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Connexins, Pannexins and Gap Junctions in Perinatal Brain Injury.
Alice McDouall, Kelly Q Zhou, Laura Bennet, Colin R Green, Alistair J Gunn

Biomedicines· June 2022

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Blocking connexin43 hemichannels prevents TGF-β2 upregulation and epithelial-mesenchymal transition in retinal pigment epithelial cells.
Heather Lyon, Naibo Yin, Ilva D Rupenthal, Colin R Green, Odunayo O Mugisho

Cell Biol Int· February 2022

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The NLRP3 inflammasome in age-related eye disease: Evidence-based connexin hemichannel therapeutics.
Odunayo O Mugisho, Colin R Green

Exp Eye Res· February 2022

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Cell transdifferentiation in ocular disease: Potential role for connexin channels.
Jie Zhang, Colin R Green, Odunayo O Mugisho

Exp Cell Res· October 2021

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Connexin therapeutics: blocking connexin hemichannel pores is distinct from blocking pannexin channels or gap junctions.
Monica L Acosta, Mohd N Mat Nor, Cindy X Guo, Odunayo O Mugisho, Frazer P Coutinho, Colin R Green

Neural Regen Res· March 2021

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Collagen I Modifies Connexin-43 Hemichannel Activity via Integrin α2β1 Binding in TGFβ1-Evoked Renal Tubular Epithelial Cells.
Joe A Potter, Gareth W Price, Chelsy L Cliff, Colin R Green, Paul E Squires

Int J Mol Sci· March 2021

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Cx31.1 expression is modulated in HaCaT cells exposed to UV-induced damage and scrape-wounding.
Louise Nugent, Boatemaa Ofori-Frimpong, Patricia E Martin, Colin R Green, Catherine S Wright

J Cell Physiol· February 2021

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Differential Action of Connexin Hemichannel and Pannexin Channel Therapeutics for Potential Treatment of Retinal Diseases.
Mohd N Mat Nor, Ilva D Rupenthal, Colin R Green, Monica L Acosta

Int J Mol Sci· February 2021

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Connexin43 hemichannel block inhibits NLRP3 inflammasome activation in a human retinal explant model of diabetic retinopathy.
Henry H Louie, Avik Shome, Charisse Yj Kuo, Ilva D Rupenthal, Colin R Green

Exp Eye Res· January 2021

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Tonabersat Inhibits Connexin43 Hemichannel Opening and Inflammasome Activation in an In Vitro Retinal Epithelial Cell Model of Diabetic Retinopathy.
Heather Lyon, Avik Shome, Ilva D Rupenthal, Colin R Green, Odunayo O Mugisho

Int J Mol Sci· December 2020

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Connexin Hemichannel Mimetic Peptide Attenuates Cortical Interneuron Loss and Perineuronal Net Disruption Following Cerebral Ischemia in Near-Term Fetal Sheep.
Panzao Yang, Joanne O Davidson, Tania M Fowke, Robert Galinsky, Guido Wassink, Colin R Green

Int J Mol Sci· September 2020

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Connexin43 Expression and Associated Chronic Inflammation Presages the Development of Cerebral Radiation Necrosis.
Lisa A Feldman, Shewta Haldankar, Simon J O'Carroll, Karen Liu, Barbara Fackelmeier, Colin R Green

J Neuropathol Exp Neurol· July 2020

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Xentry-Gap19 inhibits Connexin43 hemichannel opening especially during hypoxic injury.
Frazer P Coutinho, Colin R Green, Monica L Acosta, Ilva D Rupenthal

Drug Deliv Transl Res· June 2020

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Blocking Connexin-43 mediated hemichannel activity protects against early tubular injury in experimental chronic kidney disease.
Gareth W Price, Christos E Chadjichristos, Panagiotis Kavvadas, Sydney C W Tang, Wai Han Yiu, Colin R Green

Cell Commun Signal· May 2020

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Connexin43 hemichannel block protects against retinal pigment epithelial cell barrier breakdown.
Charisse Kuo, Colin R Green, Ilva D Rupenthal, Odunayo O Mugisho

Acta Diabetol· January 2020

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Connexin Hemichannel Block Using Orally Delivered Tonabersat Improves Outcomes in Animal Models of Retinal Disease.
Mohd Nasir Mat Nor, Ilva D Rupenthal, Colin R Green, Monica L Acosta

Neurotherapeutics· January 2020

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Targeting connexin hemichannels to control the inflammasome: the correlation between connexin43 and NLRP3 expression in chronic eye disease.
Odunayo O Mugisho, Ilva D Rupenthal, Francois Paquet-Durand, Monica L Acosta, Colin R Green

Expert Opin Ther Targets· October 2019

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Corneal Curvature: the Influence of Corneal Accommodation and Biomechanics on Corneal Shape.
Henry B Wallace, James McKelvie, Colin R Green, Stuti L Misra

Transl Vis Sci Technol· July 2019

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