Publications by authors named "Colin Sheehan"

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Tumor nutrient stress gives rise to a drug tolerant cell state in pancreatic cancer.
Colin Sheehan, Lyndon Hu, Guillaume Cognet, Grace Croley, Thao Trang Nguyen

bioRxiv· September 2025

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What's on the menu?: metabolic constraints in the pancreatic tumor microenvironment.
Colin Sheehan, Alexander Muir

J Clin Invest· July 2025

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Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis.
Patrick B Jonker, Mumina Sadullozoda, Guillaume Cognet, Juan J Apiz Saab, Kelly H Sokol, Colin Sheehan

bioRxiv· March 2025

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Catabolism of extracellular glutathione supplies amino acids to support tumor growth.
Fabio Hecht, Marco Zocchi, Emily T Tuttle, Nathan P Ward, Bradley Smith, Colin Sheehan

bioRxiv· October 2024

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Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis.
Juan J Apiz Saab, Lindsey N Dzierozynski, Patrick B Jonker, Roya AminiTabrizi, Hardik Shah, Colin Sheehan

Elife· May 2023

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Tryptophan mutations in G3BP1 tune the stability of a cellular signaling hub by weakening transient interactions with Caprin1 and USP10.
Colin T Sheehan, Thomas H Hampton, Dean R Madden

J Biol Chem· December 2022

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The requirement for mitochondrial respiration in cancer varies with disease stage.
Colin Sheehan, Alexander Muir

PLoS Biol· September 2022

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Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer.
Yogev Sela, Jinyang Li, Shivahamy Maheswaran, Robert Norgard, Salina Yuan, Colin Sheehan

Cancer Res· May 2022

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Recruitment of DNA to tumor-derived microvesicles.
James W Clancy, Colin S Sheehan, Alex C Boomgarden, Crislyn D'Souza-Schorey

Cell Rep· March 2022

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Extracellular Vesicles in the Tumor Microenvironment: Various Implications in Tumor Progression.
Alex C Boomgarden, Colin Sheehan, Crislyn D'Souza-Schorey

Adv Exp Med Biol· July 2020

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Tumor-derived extracellular vesicles: molecular parcels that enable regulation of the immune response in cancer.
Colin Sheehan, Crislyn D'Souza-Schorey

J Cell Sci· October 2019

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An ARF6-Exportin-5 axis delivers pre-miRNA cargo to tumour microvesicles.
James W Clancy, Ye Zhang, Colin Sheehan, Crislyn D'Souza-Schorey

Nat Cell Biol· July 2019

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Aberrant endocytosis leads to the loss of normal mitotic spindle orientation during epithelial glandular morphogenesis.
James W Clancy, Colin S Sheehan, Christopher J Tricarico, Crislyn D'Souza-Schorey

J Biol Chem· August 2018

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Update on nitrous oxide and its use in anesthesia practice.
Zdravka Zafirova, Colin Sheehan, Leila Hosseinian

Best Pract Res Clin Anaesthesiol· June 2018

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