Publications by authors named "Colleen Fearns"

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Targeting protein aggregation for the treatment of degenerative diseases.
Yvonne S Eisele, Cecilia Monteiro, Colleen Fearns, Sandra E Encalada, R Luke Wiseman

Nat Rev Drug Discov· November 2015

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The transthyretin amyloidoses: from delineating the molecular mechanism of aggregation linked to pathology to a regulatory-agency-approved drug.
Steven M Johnson, Stephen Connelly, Colleen Fearns, Evan T Powers, Jeffery W Kelly

J Mol Biol· August 2012

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Zinc-finger nuclease editing of human cxcr4 promotes HIV-1 CD4(+) T cell resistance and enrichment.
Jinyun Yuan, Jianbin Wang, Karen Crain, Colleen Fearns, Kenneth A Kim

Mol Ther· April 2012

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Pharmacological inhibition of BMK1 suppresses tumor growth through promyelocytic leukemia protein.
Qingkai Yang, Xianming Deng, Bingwen Lu, Michael Cameron, Colleen Fearns

Cancer Cell· September 2010

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Kinome siRNA screen identifies SMG-1 as a negative regulator of hypoxia-inducible factor-1alpha in hypoxia.
Run-Qiang Chen, Qing-Kai Yang, Yan-Ling Chen, Vasco A Oliveira, William S Dalton, Colleen Fearns

J Biol Chem· June 2009

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Nuclear factor kappaB (NF-kappaB) activation primes cells to a pro-inflammatory polarized response to a Toll-like receptor 7 (TLR7) agonist.
Jongdae Lee, Masaaki Hayashi, Jeng-Fan Lo, Colleen Fearns, Wen-Ming Chu

Biochem J· June 2009

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Combined integrin phosphoproteomic analyses and small interfering RNA--based functional screening identify key regulators for cancer cell adhesion and migration.
Yanling Chen, Bingwen Lu, Qingkai Yang, Colleen Fearns, John R Yates

Cancer Res· April 2009

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CDC25B mediates rapamycin-induced oncogenic responses in cancer cells.
Run-Qiang Chen, Qing-Kai Yang, Bing-Wen Lu, Wei Yi, Greg Cantin, Colleen Fearns

Cancer Res· March 2009

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MDP-induced interleukin-1beta processing requires Nod2 and CIAS1/NALP3.
Qilin Pan, John Mathison, Colleen Fearns, Vladimir V Kravchenko, Jean Da Silva Correia

J Leukoc Biol· July 2007

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Triad3A regulates ubiquitination and proteasomal degradation of RIP1 following disruption of Hsp90 binding.
Colleen Fearns, Qilin Pan, John C Mathison, Tsung-Hsien Chuang

J Biol Chem· November 2006

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N-(3-oxo-acyl)homoserine lactones signal cell activation through a mechanism distinct from the canonical pathogen-associated molecular pattern recognition receptor pathways.
Vladimir V Kravchenko, Gunnar F Kaufmann, John C Mathison, David A Scott, Alexander Z Katz, Colleen Fearns

J Biol Chem· September 2006

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Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4.
Christian R H Raetz, Teresa A Garrett, C Michael Reynolds, Walter A Shaw, Jeff D Moore, Colleen Fearns

J Lipid Res· May 2006

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A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy.
Masaaki Hayashi, Kyoko Imanaka-Yoshida, Toshimichi Yoshida, Malcolm Wood, Colleen Fearns

Nat Med· January 2006

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Tid1 negatively regulates the migratory potential of cancer cells by inhibiting the production of interleukin-8.
Sung-Woo Kim, Masaaki Hayashi, Jeng-Fan Lo, Colleen Fearns, Rong Xiang

Cancer Res· October 2005

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Big mitogen-activated protein kinase 1/extracellular signal-regulated kinase 5 signaling pathway is essential for tumor-associated angiogenesis.
Masaaki Hayashi, Colleen Fearns, Brian Eliceiri, Young Yang, Jiing-Dwan Lee

Cancer Res· September 2005

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Tid1 is required for T cell transition from double-negative 3 to double-positive stages.
Jeng-Fan Lo, He Zhou, Colleen Fearns, Ralph A Reisfeld, Young Yang

J Immunol· May 2005

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Tid1, the human homologue of a Drosophila tumor suppressor, reduces the malignant activity of ErbB-2 in carcinoma cells.
Sung-Woo Kim, Ta-Hsiang Chao, Rong Xiang, Jeng-Fan Lo, Michael J Campbell, Colleen Fearns

Cancer Res· November 2004

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Tid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor l(2)tid, is critical for early embryonic development and cell survival.
Jeng-Fan Lo, Masaaki Hayashi, Sung Woo-Kim, Bin Tian, Jing-Feng Huang, Colleen Fearns

Mol Cell Biol· March 2004

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MKK3 mitogen-activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury.
Leo E Otterbein, Sherrie L Otterbein, Emeka Ifedigbo, Fang Liu, Danielle E Morse, Colleen Fearns

Am J Pathol· December 2003

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Expression and role of CD14 in mice sensitized to lipopolysaccharide by Propionibacterium acnes.
Thomas Merlin, Regina Woelky-Bruggmann, Colleen Fearns, Marina Freudenberg, Regine Landmann

Eur J Immunol· March 2002

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