Publications by authors named "Colleen M Connelly"

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Synthesis, characterization and comparative biological activity of a novel set of Cu(II) complexes containing azole-based ligand frames.
Courtney E Elwell, Emily Stein, Adam Lewis, Stefan Hamaway, Kennedy A Alexis, Colleen M Connelly

J Inorg Biochem· January 2025

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Mechanistic analysis of Riboswitch Ligand interactions provides insights into pharmacological control over gene expression.
Shaifaly Parmar, Desta Doro Bume, Colleen M Connelly, Robert E Boer, Peri R Prestwood

Nat Commun· September 2024

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Parallel Discovery Strategies Provide a Basis for Riboswitch Ligand Design.
Brandon Tran, Patricio Pichling, Logan Tenney, Colleen M Connelly, Michelle H Moon

Cell Chem Biol· October 2020

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Ligand-observed NMR techniques to probe RNA-small molecule interactions.
David R Calabrese, Colleen M Connelly, John S Schneekloth

Methods Enzymol· May 2020

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Synthetic ligands for PreQ riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure.
Colleen M Connelly, Tomoyuki Numata, Robert E Boer, Michelle H Moon, Ranu S Sinniah

Nat Commun· April 2019

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Small Molecule Inhibition of MicroRNA miR-21 Rescues Chemosensitivity of Renal-Cell Carcinoma to Topotecan.
Yuta Naro, Nicholas Ankenbruck, Meryl Thomas, Yaniv Tivon, Colleen M Connelly

J Med Chem· July 2018

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Characterization of clinically used oral antiseptics as quadruplex-binding ligands.
David R Calabrese, Katherine Zlotkowski, Stephanie Alden, William M Hewitt, Colleen M Connelly

Nucleic Acids Res· April 2018

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Discovery of RNA Binding Small Molecules Using Small Molecule Microarrays.
Colleen M Connelly, Fardokht A Abulwerdi, John S Schneekloth

Methods Mol Biol· January 2018

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Discovery of Inhibitors of MicroRNA-21 Processing Using Small Molecule Microarrays.
Colleen M Connelly, Robert E Boer, Michelle H Moon, Peter Gareiss, John S Schneekloth

ACS Chem Biol· February 2017

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The Emerging Role of RNA as a Therapeutic Target for Small Molecules.
Colleen M Connelly, Michelle H Moon, John S Schneekloth

Cell Chem Biol· September 2016

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Aryl amide small-molecule inhibitors of microRNA miR-21 function.
Yuta Naro, Meryl Thomas, Matthew D Stephens, Colleen M Connelly, Alexander Deiters

Bioorg Med Chem Lett· November 2015

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Control of oncogenic miRNA function by light-activated miRNA antagomirs.
Colleen M Connelly, Alexander Deiters

Methods Mol Biol· December 2014

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Thiourea-based fluorescent chemosensors for aqueous metal ion detection and cellular imaging.
Mireille Vonlanthen, Colleen M Connelly, Alexander Deiters, Anthony Linden, Nathaniel S Finney

J Org Chem· July 2014

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Cellular microRNA sensors based on luciferase reporters.
Colleen M Connelly, Alexander Deiters

Methods Mol Biol· May 2014

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Identification of inhibitors of microRNA function from small molecule screens.
Colleen M Connelly, Alexander Deiters

Methods Mol Biol· May 2014

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Spatiotemporal control of microRNA function using light-activated antagomirs.
Colleen M Connelly, Rajendra Uprety, James Hemphill, Alexander Deiters

Mol Biosyst· November 2012

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High-throughput luciferase reporter assay for small-molecule inhibitors of microRNA function.
Colleen M Connelly, Meryl Thomas, Alexander Deiters

J Biomol Screen· July 2012

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Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma.
Douglas D Young, Colleen M Connelly, Christoph Grohmann, Alexander Deiters

J Am Chem Soc· June 2010

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