Publications by authors named "Collin Crowley"

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Murine HSD17β13 does not control liver steatosis and modestly impacts fibrosis in a sex- and diet-specific manner.
Justin D Crane, Ornella Barrandon, Bryan Faherty, Matt Gorgoglione, Collin Crowley

J Lipid Res· October 2024

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Discovery of Ervogastat (PF-06865571): A Potent and Selective Inhibitor of Diacylglycerol Acyltransferase 2 for the Treatment of Non-alcoholic Steatohepatitis.
Kentaro Futatsugi, Shawn Cabral, Daniel W Kung, Kim Huard, Esther Lee, Collin Crowley

J Med Chem· November 2022

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Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model Systems.
Trenton T Ross, Collin Crowley, Kenneth L Kelly, Anthony Rinaldi, David A Beebe

Cell Mol Gastroenterol Hepatol· November 2021

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ACC inhibitor alone or co-administered with a DGAT2 inhibitor in patients with non-alcoholic fatty liver disease: two parallel, placebo-controlled, randomized phase 2a trials.
Roberto A Calle, Neeta B Amin, Santos Carvajal-Gonzalez, Trenton T Ross, Arthur Bergman, Collin Crowley

Nat Med· October 2021

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Pharmacologic inhibition of ketohexokinase prevents fructose-induced metabolic dysfunction.
Jemy A Gutierrez, Wei Liu, Sylvie Perez, Gang Xing, Gabriele Sonnenberg, Collin Crowley

Mol Metab· June 2021

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Optimizing the Benefit/Risk of Acetyl-CoA Carboxylase Inhibitors through Liver Targeting.
Kim Huard, Aaron C Smith, Gregg Cappon, Robert L Dow, David J Edmonds, Collin Crowley

J Med Chem· October 2020

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Targeting diacylglycerol acyltransferase 2 for the treatment of nonalcoholic steatohepatitis.
Neeta B Amin, Santos Carvajal-Gonzalez, Julie Purkal, Tong Zhu, Collin Crowley

Sci Transl Med· November 2019

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