Publications by authors named "Collin D Heer"

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Somatic CRISPR tumorigenesis and multiomic analysis reveal a pentose phosphate pathway disruption vulnerability in MPNSTs.
Gavin R McGivney, Qierra R Brockman, Nicholas Borcherding, Amanda Scherer, Adam J Rauckhorst, Collin D Heer

Sci Adv· August 2025

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NAPRT expression and epigenetic regulation in pediatric rhabdomyosarcoma as a potential biomarker for NAMPT inhibition.
Angela Kim, Prateek Bhardwaj, Collin D Heer, Sophia J Zhao, Karlie N Lucas

bioRxiv· July 2025

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Mitoregulin Promotes Cell Cycle Progression in Non-Small Cell Lung Cancer Cells.
Colleen S Stein, Connor R Linzer, Collin D Heer, Nathan H Witmer, Jesse D Cochran

Int J Mol Sci· February 2025

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Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide-induced microglial and astrocytic neuroinflammation by increasing NAD.
Jureepon Roboon, Tsuyoshi Hattori, Hiroshi Ishii, Mika Takarada-Iemata, Dinh Thi Nguyen, Collin D Heer

J Neurochem· July 2021

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Avasopasem manganese synergizes with hypofractionated radiation to ablate tumors through the generation of hydrogen peroxide.
Brock J Sishc, Lianghao Ding, Taek-Keun Nam, Collin D Heer, Samuel N Rodman

Sci Transl Med· May 2021

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Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity.
Collin D Heer, Daniel J Sanderson, Lynden S Voth, Yousef M O Alhammad, Mark S Schmidt

J Biol Chem· December 2020

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Succinate Accumulation Links Mitochondrial MnSOD Depletion to Aberrant Nuclear DNA Methylation and Altered Cell Fate.
Kimberly L Cramer-Morales, Collin D Heer, Kranti A Mapuskar, Frederick E Domann

J Exp Pathol (Wilmington)· December 2020

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Coronavirus infection and PARP expression dysregulate the NAD Metabolome: an actionable component of innate immunity.
Collin D Heer, Daniel J Sanderson, Lynden S Voth, Yousef M O Alhammad, Mark S Schmidt

bioRxiv· October 2020

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Letting off electrons to cope with metabolic stress.
Collin D Heer, Charles Brenner

Nat Metab· June 2020

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Superoxide Dismutase Mimetic GC4419 Enhances the Oxidation of Pharmacological Ascorbate and Its Anticancer Effects in an H₂O₂-Dependent Manner.
Collin D Heer, Andrew B Davis, David B Riffe, Brett A Wagner, Kelly C Falls

Antioxidants (Basel)· January 2018

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SOD2 targeted gene editing by CRISPR/Cas9 yields Human cells devoid of MnSOD.
Kimberly Cramer-Morales, Collin D Heer, Kranti A Mapuskar, Frederick E Domann

Free Radic Biol Med· December 2015

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