Publications by authors named "Concepcion Alonso"

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Sensitivity enhancement of a lossy mode resonance immunosensor using gold-nanoparticles for the detection of vascular endothelial growth factor protein.
Melanys Benítez, Ignacio R Matías, Pablo Zubiate, Sukayna Ezquerro, Enrique Azuaje-Hualde, Concepción Alonso

Talanta· January 2026

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A patent review of topoisomerase 1 inhibitors (2021-present).
Maria Fuertes, Endika Martín-Encinas, Asier Selas, Concepcion Alonso

Expert Opin Ther Pat· January 2026

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Platinum(II) complexes with 4,5-diazafluorene ligands: Synthesis, structural features, and in vitro antiproliferative evaluation.
Leonardo Sandin-Mazzondo, Jesús M Martínez-Ilarduya, Concepción Alonso, Camino Bartolomé

Eur J Med Chem· December 2025

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Sulfadoxine derivatization through multicomponent reactions to obtain new antiplasmodial compounds.
Angela Trejo, Yunuen Avalos-Padilla, Concepción Alonso, Xavier Fernàndez-Busquets, Carme Masdeu

Bioorg Med Chem· November 2025

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4,5-Diazafluorene derivatives and their silver(I) complexes: Synthesis and biological evaluation as antiproliferative agents.
Leonardo Sandin-Mazzondo, Angela Trejo, Mariachiara Mammone, Maria Grazia Perrone, Marialessandra Contino, Concepción Alonso

Eur J Med Chem· August 2025

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Investigational DNA topoisomerase I inhibitors for colorectal cancer: preclinical and early phase developments.
Endika Martin-Encinas, Maria Fuertes, Carme Masdeu, Asier Selas, Concepcion Alonso

Expert Opin Investig Drugs· August 2025

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Phosphine Oxide Indenoquinoline Derivatives: Synthesis and Biological Evaluation as Topoisomerase I Inhibitors and Antiproliferative Agents.
Alba Rodriguez-Paniagua, Cinzia Tesauro, Birgitta R Knudsen, Maria Fuertes, Concepción Alonso

Molecules· December 2024

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Synthesis, biological and computational evaluation of novel cyanomethyl vinyl ether derivatives.
Endika Martín-Encinas, María Fuertes, Samuel Delgado-Hernández, Fernando García-Tellado, David Tejedor, Concepción Alonso

Front Pharmacol· March 2024

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Aza-Povarov Reaction. A Method for the Synthesis of Fused Tetracyclic Chromeno[4,3-]pyrido[1,2-]pyrimidines.
Endika Martín-Encinas, Leyre Lopez-Aguileta, Francisco Palacios, Concepción Alonso

J Org Chem· January 2024

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Antileishmanial Effect of 1,5- and 1,8-Substituted Fused Naphthyridines.
Estela Melcón-Fernandez, Endika Martín-Encinas, Francisco Palacios, Gulio Galli, Rosa M Reguera, Concepción Alonso

Molecules· December 2023

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Impact of concurrent tumour events on the prostate cancer outcomes of germline BRCA2 mutation carriers.
Rebeca Lozano, Elena Castro, Fernando Lopez-Campos, Heather Thorne, Miguel Ramirez-Backhaus, Concepción Alonso

Eur J Cancer· May 2023

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The Intramolecular Povarov Tool in the Construction of Fused Nitrogen-Containing Heterocycles.
Carme Masdeu, Jesús M de Los Santos, Francisco Palacios, Concepción Alonso

Top Curr Chem (Cham)· May 2023

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Gel-Free Tools for Quick and Simple Screening of Anti-Topoisomerase 1 Compounds.
Josephine Geertsen Keller, Kamilla Vandsø Petersen, Karol Mizielinski, Celine Thiesen, Lotte Bjergbæk, Concepcion Alonso

Pharmaceuticals (Basel)· April 2023

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Efficient AntiMycolata Agents by Increasing the Lipophilicity of Known Antibiotics through Multicomponent Reactions.
Angela Trejo, Carme Masdeu, Irene Serrano-Pérez, Marina Pedrola, Narcís Juanola, Concepción Alonso

Antibiotics (Basel)· January 2023

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The design and discovery of topoisomerase I inhibitors as anticancer therapies.
Endika Martín-Encinas, Asier Selas, Francisco Palacios, Concepción Alonso

Expert Opin Drug Discov· June 2022

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Hydrogen sulphide-triggered theranostic prodrugs based on the dynamic chemistry of tetrazines.
Marcelle D Perretti, Yaiza Pérez-Pérez, Kevin Soler-Carracedo, Endika Martín-Encinas, Concepción Alonso

Chem Commun (Camb)· May 2022

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Multicomponent Synthesis of Unsaturated γ-Lactam Derivatives. Applications as Antiproliferative Agents through the Bioisosterism Approach: Carbonyl vs. Phosphoryl Group.
Xabier Del Corte, Adrián López-Francés, Ilia Villate-Beitia, Myriam Sainz-Ramos, Edorta Martínez de Marigorta, Concepción Alonso

Pharmaceuticals (Basel)· April 2022

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Synthesis of hybrid phosphorated indenoquinolines and biological evaluation as topoisomerase I inhibitors and antiproliferative agents.
María Fuertes, Asier Selas, Angela Trejo, Birgitta R Knudsen, Francisco Palacios, Concepción Alonso

Bioorg Med Chem Lett· February 2022

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Naphthyridine Derivatives Induce Programmed Cell Death in .
Aitor Rizo-Liendo, Iñigo Arberas-Jiménez, Endika Martin-Encinas, Ines Sifaoui, María Reyes-Batlle, Concepción Alonso

Pharmaceuticals (Basel)· October 2021

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Hybrid Quinolinyl Phosphonates as Heterocyclic Carboxylate Isosteres: Synthesis and Biological Evaluation against Topoisomerase 1B (TOP1B).
Asier Selas, María Fuertes, Estela Melcón-Fernández, Yolanda Pérez-Pertejo, Rosa M Reguera, Concepcion Alonso

Pharmaceuticals (Basel)· August 2021

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Simple and Fast DNA Based Sensor System for Screening of Small-Molecule Compounds Targeting Eukaryotic Topoisomerase 1.
Kamilla Vandsø Petersen, Asier Selas, Kirstine Mejlstrup Hymøller, Karol Mizielinski, Maria Thorsager, Concepcion Alonso

Pharmaceutics· August 2021

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A Dual-Sensor-Based Screening System for In Vitro Selection of TDP1 Inhibitors.
Ann-Katrine Jakobsen, Josephine Geertsen Keller, María Gonzalez, Endika Martin-Encinas, Francisco Palacios, Concepcion Alonso

Sensors (Basel)· July 2021

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A patent review of topoisomerase I inhibitors (2016-present).
Asier Selas, Endika Martin-Encinas, Maria Fuertes, Carme Masdeu, Gloria Rubiales, Concepción Alonso

Expert Opin Ther Pat· June 2021

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Fused chromeno and quinolino[1,8]naphthyridines: Synthesis and biological evaluation as topoisomerase I inhibitors and antiproliferative agents.
Endika Martín-Encinas, Gloria Rubiales, Birgitta R Knudsen, Francisco Palacios, Concepción Alonso

Bioorg Med Chem· June 2021

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Familial hypercholesterolemia: A single-nucleotide variant (SNV) in mosaic at the low density lipoprotein receptor (LDLR).
Sonia Rodríguez-Nóvoa, Carmen Rodríguez-Jiménez, Concepción Alonso, Lara Rodriguez-Laguna, Gema Gordo

Atherosclerosis· October 2020

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