Publications by authors named "Congjun Xu"

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Discovery of novel 2,4,5,6-tetrahydro-7H-pyrazolo[3,4-c]pyridine-7-one derivatives as PDE2 inhibitors with Alzheimer's disease therapeutic potential.
Fan Yang, Qi Guo, Mingbin Chen, Wei Wang, Xinyi Chen, Congjun Xu

Eur J Med Chem· January 2026

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Design, synthesis, and induction of tumor ferroptosis activity of a novel FSP1 protein degrading agent.
Yanhong Huang, Qiao Liu, Jinzhuo Li, Mingyu Cheng, Rui Su, Congjun Xu

Eur J Med Chem· January 2026

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Nitric oxide releasing ecologically friendly tannic acid based antibacterial hydrogel as flexible electronics.
Yuxing Ma, Ziyu Qin, Guanghua Xia, Congjun Xu, Shuting Zhang

Colloids Surf B Biointerfaces· October 2025

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Discovery of Rigid Linker-Based IRAK4 PROTACs with Improved Metabolic Stability for the Treatment of Inflammatory Diseases.
Yapeng Fan, Rongxiang Ma, Kabonde Makasa Njobvu, Yifan Wang, Yichang Ren, Congjun Xu

J Med Chem· August 2025

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Discovery of structurally intriguing diterpenoids as anti-neuroinflammatory agents from mangrove plant Excoecaria agallocha L. via inhibiting macrophage polarization and inflammasome.
Jun-Yi Li, Ming-Bin Chen, Ting-Ting Fu, Fei-Fei Liu, Jin Liu, Cong-Jun Xu

Phytochemistry· June 2025

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Discovery of novel rigid STING PROTAC degraders as potential therapeutics for acute kidney injury.
Rongxiang Ma, Renquan Fu, Yifan Wang, Kabonde Makasa Njobvu, Yapeng Fan, Congjun Xu

Eur J Med Chem· June 2025

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Identification of 1,2,3,4,6-O-Pentagalloylglucose as a novel ASNS inhibitor for MASLD amelioration in mice by increasing l-aspartate levels alongside LKB1/AMPK metabolic axis activation.
Ting-Ting Fu, Ren-Quan Fu, Hai-Qing Liu, Hui-Ling Fu, Rui Su, Cong-Jun Xu

Int Immunopharmacol· June 2025

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Development of a Highly Selective Ferroptosis Inducer Targeting GPX4 with 2-Ethynylthiazole-4-carboxamide as Electrophilic Warhead.
Sunkai Gu, Guanyu Yang, Hongyuan Bian, Fan Yang, Yajing Zhang, Congjun Xu

J Med Chem· February 2025

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A GSH-responsive oxidative stress nanoamplifier for self-augmented chemo/chemodynamic therapy to reverse cisplatin resistance.
Yanjuan Huang, Meng Xia, Congjun Xu, Zijun Lin, Meixu Chen

Acta Biomater· January 2025

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Natural linoleic acid from marine fungus Eutypella sp. F0219 blocks KEAP1/NRF2 interaction and ameliorates MASLD by targeting FABP4.
Chen-Yan Wu, Yue Chen, Meng-Ting Chen, Ting-Ting Fu, Jin Liu, Cong-Jun Xu

Free Radic Biol Med· November 2024

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Amplifying hepatic L-aspartate levels suppresses CCl-induced liver fibrosis by reversing glucocorticoid receptor β-mediated mitochondrial malfunction.
Rui Su, Hui-Ling Fu, Qian-Xue Zhang, Chen-Yan Wu, Guan-Yu Yang, Cong-Jun Xu

Pharmacol Res· August 2024

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Corrigendum: Taxonomic and functional β-diversity patterns reveal stochastic assembly rules in microbial communities of seagrass beds.
Xiaofeng Niu, Wenjing Ren, Congjun Xu, Ruilong Wang, Jingwei Zhang

Front Plant Sci· August 2024

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Ent-eudesmane sesquiterpenoids with anti-neuroinflammatory activity from the marine-derived fungus Eutypella sp. F0219.
Zhong-Ping Jiang, Rui Su, Meng-Ting Chen, Jun-Yi Li, Han-Yu Chen, Cong-Jun Xu

Phytochemistry· July 2024

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Discovery of novel melatonin-mydroxyquinoline hybrids as multitarget strategies for Alzheimer's disease therapy.
Wei Wang, Tingting Pan, Rui Su, Mingbin Chen, Wandi Xiong, Congjun Xu

Front Chem· April 2024

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Taxonomic and functional β-diversity patterns reveal stochastic assembly rules in microbial communities of seagrass beds.
Xiaofeng Niu, Wenjing Ren, Congjun Xu, Ruilong Wang, Jingwei Zhang

Front Plant Sci· February 2024

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Identification of a natural PLA2 inhibitor from the marine fungus sp. c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting the IRE-1/XBP-1s axis and JNK signaling.
Yong Rao, Rui Su, Chenyan Wu, Xingxing Chai, Jinjian Li, Congjun Xu

Acta Pharm Sin B· January 2024

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Marine fungus c1. sp metabolite activates the HSF1/PGC-1α axis, inducing a thermogenic program for treating obesity.
Yong Rao, Rui Su, Chenyan Wu, Guanyu Yang, Renquan Fu, Congjun Xu

Front Pharmacol· January 2024

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Assessment of greenhouse gases emissions and intensity from Chinese marine aquaculture in the past three decades.
Congjun Xu, Guohuan Su, Kangshun Zhao, Huan Wang, Xiaoqi Xu, Jun Xu

J Environ Manage· March 2023

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A facile method for anti-cancer drug encapsulation into polymersomes with a core-satellite structure.
Hongchao Xu, Weiwei Cui, Zhitao Zong, Yinqiu Tan, Congjun Xu

Drug Deliv· December 2022

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Reactive oxygen species-activated self-amplifying prodrug nanoagent for tumor-specific Cu-chelate chemotherapy and cascaded photodynamic therapy.
Jie Chen, Xiaomin Tan, Yanjuan Huang, Congjun Xu, Zishan Zeng, Xiaoyu Xu

Biomaterials· May 2022

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Phototriggered Self-Adaptive Functionalized MOC-Based Drug Delivery Platform Promises High Antitumor Efficacy.
Yifeng Shen, Congjun Xu, Jie Chen, Zilin Guan, Yanjuan Huang, Xiaoyu Xu

Adv Healthc Mater· October 2021

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Discovery of a Potent Glutathione Peroxidase 4 Inhibitor as a Selective Ferroptosis Inducer.
Congjun Xu, Zhanghong Xiao, Jing Wang, Hualu Lai, Tao Zhang, Meixu Chen

J Med Chem· September 2021

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Reduction-responsive dehydroepiandrosterone prodrug nanoparticles loaded with camptothecin for cancer therapy by enhancing oxidation therapy and cell replication inhibition.
Congjun Xu, Haolan Yang, Zhanghong Xiao, Tao Zhang, Zilin Guan, Xiaoyu Xu

Int J Pharm· June 2021

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Discovery of 4-Arylindolines Containing a Thiazole Moiety as Potential Antitumor Agents Inhibiting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction.
Mingze Qin, Yangyang Meng, Haoshen Yang, Lei Liu, Haotian Zhang, Congjun Xu

J Med Chem· May 2021

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[Identification of keystone predators in Haizhou Bay food web based on the revised SURF index].
Cong-Jun Xu, Chong-Liang Zhang, Bin-Duo Xu, Yi-Ping Ren, Ying Xue

Ying Yong Sheng Tai Xue Bao· November 2020

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