Publications by authors named "Connor Weidle"

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Bottom-up design of Ca channels from defined selectivity filter geometry.
Yulai Liu, Connor Weidle, Ljubica Mihaljević, Joseph L Watson, Zhe Li

Nature· December 2025

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Atomically accurate de novo design of antibodies with RFdiffusion.
Nathaniel R Bennett, Joseph L Watson, Robert J Ragotte, Andrew J Borst, DéJenaé L See, Connor Weidle

Nature· November 2025

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Computational design of bifaceted protein nanomaterials.
Sanela Rankovic, Kenneth D Carr, Justin Decarreau, Rebecca Skotheim, Ryan D Kibler, Connor Weidle

Nat Mater· October 2025

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De novo design of RNA and nucleoprotein complexes.
Andrew Favor, Riley Quijano, Elizaveta Chernova, Andrew Kubaney, Connor Weidle

bioRxiv· October 2025

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De novo design of potent inhibitors of clostridial family toxins.
Robert J Ragotte, Huazhu Liang, John Tam, Sean Miletic, Jacob M Berman, Connor Weidle

Proc Natl Acad Sci U S A· September 2025

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Protein identification using Cryo-EM and artificial intelligence guides improved sample purification.
Kenneth D Carr, Dane Evan D Zambrano, Connor Weidle, Alex Goodson, Helen E Eisenach

J Struct Biol X· June 2025

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Elicitation of liver-stage immunity by nanoparticle immunogens displaying P. falciparum CSP-derived antigens.
Mark D Langowski, Joseph R Francica, Alex L Roederer, Nicholas K Hurlburt, Justas V Rodarte, Connor Weidle

NPJ Vaccines· May 2025

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Atomically accurate de novo design of antibodies with RFdiffusion.
Nathaniel R Bennett, Joseph L Watson, Robert J Ragotte, Andrew J Borst, DéJenaé L See, Connor Weidle

bioRxiv· February 2025

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Solubilization of Membrane Proteins using designed protein WRAPS.
Ljubica Mihaljević, David E Kim, Helen E Eisenach, Pooja D Bandawane, Andrew J Borst, Connor Weidle

bioRxiv· February 2025

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Computational design of bifaceted protein nanomaterials.
Sanela Rankovic, Kenneth D Carr, Justin Decarreau, Rebecca Skotheim, Ryan D Kibler, Connor Weidle

bioRxiv· December 2024

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Bottom-up design of calcium channels from defined selectivity filter geometry.
Yulai Liu, Connor Weidle, Ljubica Mihaljević, Joseph L Watson, Zhe Li

bioRxiv· December 2024

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De novo design of allosterically switchable protein assemblies.
Arvind Pillai, Abbas Idris, Annika Philomin, Connor Weidle, Rebecca Skotheim

Nature· August 2024

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Blueprinting extendable nanomaterials with standardized protein blocks.
Timothy F Huddy, Yang Hsia, Ryan D Kibler, Jinwei Xu, Neville Bethel, Connor Weidle

Nature· March 2024

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Accurate computational design of three-dimensional protein crystals.
Zhe Li, Shunzhi Wang, Una Nattermann, Asim K Bera, Andrew J Borst, Connor Weidle

Nat Mater· December 2023

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Blueprinting expandable nanomaterials with standardized protein building blocks.
Timothy F Huddy, Yang Hsia, Ryan D Kibler, Jinwei Xu, Neville Bethel, Connor Weidle

bioRxiv· June 2023

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Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
Justas V Rodarte, Carly Baehr, Dustin Hicks, Tyler L Liban, Connor Weidle

Structure· January 2023

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Characterization of a vaccine-elicited human antibody with sequence homology to VRC01-class antibodies that binds the C1C2 gp120 domain.
Matthew D Gray, Junli Feng, Connor E Weidle, Kristen W Cohen, Lamar Ballweber-Fleming

Sci Adv· May 2022

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Protective antibodies against human parainfluenza virus type 3 infection.
Jim Boonyaratanakornkit, Suruchi Singh, Connor Weidle, Justas Rodarte, Ramasamy Bakthavatsalam

MAbs· January 2022

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Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Emilie Seydoux, Yu-Hsin Wan, Junli Feng, Abigail Wall, Safia Aljedani, Connor Weidle

Cell Rep· July 2021

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Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Emilie Seydoux, Yu-Hsin Wan, Junli Feng, Abigail Wall, Safia Aljedani, Connor Weidle

Cell Rep· May 2021

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HIV-1 VRC01 Germline-Targeting Immunogens Select Distinct Epitope-Specific B Cell Receptors.
Yu-Ru Lin, K Rachael Parks, Connor Weidle, Anika S Naidu, Arineh Khechaduri

Immunity· October 2020

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Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization.
K Rachael Parks, Anna J MacCamy, Josephine Trichka, Matthew Gray, Connor Weidle

Cell Rep· December 2019

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Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes.
Tara Bancroft, Blair L DeBuysscher, Connor Weidle, Allison Schwartz, Abigail Wall

J Exp Med· October 2019

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Anti-idiotypic antibodies elicit anti-HIV-1-specific B cell responses.
Pia Dosenovic, Anna-Klara Pettersson, Abigail Wall, Eddy S Thientosapol, Junli Feng, Connor Weidle

J Exp Med· October 2019

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Author Correction: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Neville K Kisalu, Azza H Idris, Connor Weidle, Yevel Flores-Garcia, Barbara J Flynn

Nat Med· January 2019

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