Publications by authors named "Constantin Georgescu"

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Anthrax toxins exacerbate sepsis-induced coagulopathy and endothelial dysfunction in a baboon model of anthrax.
Ravi S Keshari, Robert Silasi, Stephanie D Byrum, Narcis I Popescu, Girija Regmi, Constantin Georgescu

J Thromb Haemost· November 2025

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Hepatocyte MLKL Drives Obesity-Driven Hepatocellular Carcinoma Progression via Mitochondrial Dysfunction Independent of Necroptosis in MASLD.
Phoebe Ohene-Marfo, Sabira Mohammed, Chao Jiang, Shylesh Bhaskaran, Constantin Georgescu

bioRxiv· November 2025

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Protective effects of factor XI inhibition by abelacimab in a baboon model of live Staphylococcus aureus sepsis.
Robert Silasi, Ravi S Keshari, Tomohiro Abe, Stephanie D Byrum, Girija Regmi, Constantin Georgescu

J Thromb Haemost· October 2025

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Publisher Correction: Tetraspanin-enriched membrane domains regulate vascular leakage by altering membrane cholesterol accessibility to balance antagonistic GTPases.
Yingjun Ding, Junxiong Chen, Songlan Liu, Jennifer M Hays, Xiaowu Gu, Constantin Georgescu

Nat Cardiovasc Res· September 2025

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Tetraspanin-enriched membrane domains regulate vascular leakage by altering membrane cholesterol accessibility to balance antagonistic GTPases.
Yingjun Ding, Junxiong Chen, Songlan Liu, Jennifer M Hays, Xiaowu Gu, Constantin Georgescu

Nat Cardiovasc Res· August 2025

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Multimodal Analysis of Sepsis-induced Cardiomyopathy in a Baboon Model.
Tomohiro Abe, Robert Silasi, Ravi S Keshari, Narcis Popescu, Girija Regmi, Constantin Georgescu

bioRxiv· June 2025

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A Non-canonical Role for Hepatocyte MLKL in Promoting Mitochondrial Dysfunction and Senescence in the Aging Liver.
Sabira Mohammed, Chao Jiang, Travis Pennington, Shylesh Bhaskaran, Phoebe Ohene-Marfo, Constantin Georgescu

bioRxiv· May 2025

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Spatial transcriptomics delineates potential differences in intestinal phenotypes of cardiac and classical necrotizing enterocolitis.
Kathryn Y Burge, Constantin Georgescu, Hua Zhong, Adam P Wilson, Aarthi Gunasekaran

iScience· April 2025

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Sulforaphane acutely activates multiple starvation response pathways.
Kendra S Plafker, Constantin Georgescu, Nathan Pezant, Atul Pranay, Scott M Plafker

Front Nutr· January 2025

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Unacylated Ghrelin Protects Against Age-Related Loss of Muscle Mass and Contractile Dysfunction in Skeletal Muscle.
Hyunyoung Kim, Rojina Ranjit, Dennis R Claflin, Constantin Georgescu, Jonathan D Wren

Aging Cell· December 2024

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The nitrone compound OKN-007 delays motor neuron loss and disease progression in the G93A mouse model of amyotrophic lateral sclerosis.
Shylesh Bhaskaran, Katarzyna M Piekarz, Jacob Brown, Brian Yang, Sarah R Ocañas, Constantin Georgescu

Front Neurosci· November 2024

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Dynamics of microRNA secreted via extracellular vesicles during the maturation of embryonic stem cell-derived retinal pigment epithelium.
Dimitrios Pollalis, Gopa Kumar Gopinadhan Nair, Justin Leung, Clarisa Marie Bloemhof, Jeffrey K Bailey, Constantin Georgescu

J Extracell Biol· September 2024

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CD151 Maintains Endolysosomal Protein Quality to Inhibit Vascular Inflammation.
Junxiong Chen, Yingjun Ding, Chao Jiang, Rongmei Qu, Jonathan D Wren, Constantin Georgescu

Circ Res· May 2024

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Rescuing Photoreceptors in RPE Dysfunction-Driven Retinal Degeneration: The Role of Small Extracellular Vesicles Secreted from Retinal Pigment Epithelium.
Dimitrios Pollalis, Constantin Georgescu, Jonathan D Wren, Grigor Tombulyan, Justin M Leung

bioRxiv· April 2024

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Autoantibodies identify primary Sjögren's syndrome in patients lacking serum IgG specific for Ro/SS-A and La/SS-B.
Sherri Longobardi, Charmaine Lopez-Davis, Bhuwan Khatri, Constantin Georgescu, Cherilyn Pritchett-Frazee

Ann Rheum Dis· September 2023

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Absence of Either Ripk3 or Mlkl Reduces Incidence of Hepatocellular Carcinoma Independent of Liver Fibrosis.
Sabira Mohammed, Nidheesh Thadathil, Phoebe Ohene-Marfo, Albert L Tran, Michael Van Der Veldt, Constantin Georgescu

Mol Cancer Res· September 2023

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An unbiased seed-based RNAi selection screen identifies small RNAs that inhibit androgen signaling and prostate cancer cell growth.
Joshua M Corbin, Constantin Georgescu, Lin Wang, Jonathan D Wren, Magdalena Bieniasz

Mol Ther Nucleic Acids· September 2023

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Anti-miR-93-5p therapy prolongs sepsis survival by restoring the peripheral immune response.
Mihnea P Dragomir, Enrique Fuentes-Mattei, Melanie Winkle, Keishi Okubo, Recep Bayraktar, Constantin Georgescu

J Clin Invest· July 2023

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Dietary protection against the visual and motor deficits induced by experimental autoimmune encephalomyelitis.
Katarzyna Zyla-Jackson, Dorothy A Walton, Kendra S Plafker, Susan Kovats, Constantin Georgescu

Front Neurol· March 2023

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The Isolation and In Vitro Differentiation of Primary Fetal Baboon Tracheal Epithelial Cells for the Study of SARS-CoV-2 Host-Virus Interactions.
Bharathiraja Subramaniyan, Sunam Gurung, Manish Bodas, Andrew R Moore, Jason L Larabee, Constantin Georgescu

Viruses· March 2023

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Lipid hydroperoxides and oxylipins are mediators of denervation induced muscle atrophy.
Jacob L Brown, Fredrick F Peelor, Constantin Georgescu, Jonathan D Wren, Michael Kinter

Redox Biol· November 2022

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Detecting anomalous referencing patterns in PubMed papers suggestive of author-centric reference list manipulation.
Jonathan D Wren, Constantin Georgescu

Scientometrics· October 2022

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Developing immortal cell lines from embryos four novel cell lines derived from .
Gary J Gorbsky, John R Daum, Hem Sapkota, Katja Summala, Hitoshi Yoshida, Constantin Georgescu

Open Biol· July 2022

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A novel sulindac derivative protects against oxidative damage by a cyclooxygenase-independent mechanism.
Shailaja Kesaraju Allani, Ramanjaneyulu Rayala, Oscar Rivera, Howard M Prentice, Xi Chen, Constantin Georgescu

J Pharmacol Exp Ther· June 2022

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Proteomic Insight into the Role of Exosomes in Proliferative Vitreoretinopathy Development.
Gopa Kumar Gopinadhan Nair, Dimitrios Pollalis, Jonathan D Wren, Constantin Georgescu, Virginie Sjoelund

J Clin Med· May 2022

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