Publications by authors named "Constanze Depp"

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The circadian clock regulates scavenging of fluid-borne substrates by brain border-associated macrophages.
Helena J Barr, Sydney K Caldwell, Justin M Reimertz, Constanze Depp, Alec J Walker

bioRxiv· December 2025

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Conserved phenotype and function of human brain border-associated macrophages in iPSC-derived models.
Helena J Barr, Constanze Depp, Maximilian Hingerl, Trang Nguyen, Justin M Reimertz

bioRxiv· December 2025

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White matters arising: Rethinking Alzheimer's disease through the lens of myelin.
Constanze Depp

Science· October 2025

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Microglia transcriptional states and their functional significance: Context drives diversity.
Constanze Depp, Jordan L Doman, Maximilian Hingerl, Judy Xia, Beth Stevens

Immunity· May 2025

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Parental origin of transgene modulates amyloid-β plaque burden in the 5xFAD mouse model of Alzheimer's disease.
Andrew Octavian Sasmita, Erinne Cherisse Ong, Taisiia Nazarenko, Shuying Mao, Lina Komarek, Constanze Depp

Neuron· March 2025

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Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.
Seiji Kaji, Stefan A Berghoff, Lena Spieth, Lennart Schlaphoff, Andrew O Sasmita, Constanze Depp

Immunity· January 2025

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Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.
Seiji Kaji, Stefan A Berghoff, Lena Spieth, Lennart Schlaphoff, Andrew O Sasmita, Constanze Depp

Immunity· November 2024

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Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer's disease model mice.
Andrew Octavian Sasmita, Constanze Depp, Taisiia Nazarenko, Ting Sun, Sophie B Siems

Nat Neurosci· September 2024

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Downregulated expression of lactate dehydrogenase in adult oligodendrocytes and its implication for the transfer of glycolysis products to axons.
Erik Späte, Baoyu Zhou, Ting Sun, Kathrin Kusch, Ebrahim Asadollahi, Constanze Depp

Glia· August 2024

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Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease.
Constanze Depp, Ting Sun, Andrew Octavian Sasmita, Lena Spieth, Stefan A Berghoff

Nature· June 2023

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Isolated catatonia-like executive dysfunction in mice with forebrain-specific loss of myelin integrity.
Sahab Arinrad, Constanze Depp, Sophie B Siems, Andrew Octavian Sasmita, Maria A Eichel

Elife· March 2023

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Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice.
Stefan A Berghoff, Lena Spieth, Ting Sun, Leon Hosang, Constanze Depp

Cell Rep· October 2021

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Live Imaging of the Mitochondrial Glutathione Redox State in Primary Neurons using a Ratiometric Indicator.
Athanasios Katsalifis, Angela Maria Casaril, Constanze Depp, Carlos Bas-Orth

J Vis Exp· October 2021

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Hippocampal neurons respond to brain activity with functional hypoxia.
Umer Javed Butt, Agnes A Steixner-Kumar, Constanze Depp, Ting Sun, Imam Hassouna

Mol Psychiatry· June 2021

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CaMKIIα Expressing Neurons to Report Activity-Related Endogenous Hypoxia upon Motor-Cognitive Challenge.
Umer Javed Butt, Imam Hassouna, Laura Fernandez Garcia-Agudo, Agnes A Steixner-Kumar, Constanze Depp

Int J Mol Sci· March 2021

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Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis.
Stefan A Berghoff, Lena Spieth, Ting Sun, Leon Hosang, Lennart Schlaphoff, Constanze Depp

Nat Neurosci· January 2021

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A single, open access journal may prevent the primary publishing problems in the life sciences.
Philip Lewis, Constanze Depp

Account Res· August 2019

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An emerging role of dysfunctional axon-oligodendrocyte coupling in neurodegenerative diseases.
Alexandra I Mot, Constanze Depp, Klaus-Armin Nave

Dialogues Clin Neurosci· December 2018

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Synaptic Activity Protects Neurons Against Calcium-Mediated Oxidation and Contraction of Mitochondria During Excitotoxicity.
Constanze Depp, Carlos Bas-Orth, Lisa Schroeder, Andrea Hellwig, Hilmar Bading

Antioxid Redox Signal· October 2018

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Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells.
Amy M Smith, Constanze Depp, Brent J Ryan, Geoffrey I Johnston, Javier Alegre-Abarrategui

Mov Disord· October 2018

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