Publications by authors named "Corey Strickland"

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Pembrolizumab microgravity crystallization experimentation.
Paul Reichert, Winifred Prosise, Thierry O Fischmann, Giovanna Scapin, Chakravarthy Narasimhan, April Spinale, Ray Polniak, Xiaoyu Yang, Erika Walsh, Daya Patel

NPJ Microgravity· December 2019

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Discovery of a Novel Series of -Indolinone-Based Glutarimides as Highly Efficacious and Selective IKZF2 Molecular Glue Degraders.
Xuqing Zhang, Harshil Dhruv, Qiaolin Deng, Matthew Tudor, Nelisa Bechtel, Corey Strickland

J Med Chem· September 2025

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Overcoming CK1α liability in the discovery of a series of isoIndolinone Glutarimides as selective IKZF2 molecular glue degraders.
Xuqing Zhang, Qiaolin Deng, Harshil Dhruv, Matthew Tudor, Rakesh Nagilla, Corey O Strickland

Bioorg Med Chem Lett· August 2025

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Discovery and Characterization of PVTX-321 as a Potent and Orally Bioavailable Estrogen Receptor Degrader for ER+/HER2- Breast Cancer.
Guozhang Xu, Courtney G Havens, Qiaolin Deng, Cassandra Lowenstein, Debangshu Samanta, Corey Strickland

J Med Chem· June 2025

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Development of PVTX-405 as a potent and highly selective molecular glue degrader of IKZF2 for cancer immunotherapy.
Zhixiang Chen, Harshil Dhruv, Xuqing Zhang, Rohan Kalyan Rej, Longchuan Bai, Corey O Strickland

Nat Commun· May 2025

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Discovery of Potent, Highly Selective, and Efficacious SMARCA2 Degraders.
Zhenwu Li, Lalgudi S Harikrishnan, Guozhang Xu, Debangshu Samanta, Jose C Clemente, Corey Strickland

J Med Chem· January 2025

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Discovery of SMD-3236: A Potent, Highly Selective and Efficacious SMARCA2 Degrader for the Treatment of SMARC4-Deficient Human Cancers.
Lin Yang, Wenbin Tu, Lingying Leng, Liyue Huang, Wei Jiang, Corey Strickland

J Med Chem· January 2025

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Identification, structural, and biophysical characterization of a positive modulator of human Kv3.1 channels.
Yun-Ting Chen, Mee Ra Hong, Xin-Jun Zhang, James Kostas, Yuxing Li, Corey Strickland

Proc Natl Acad Sci U S A· October 2023

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Discovery and Structure-Based Design of Macrocyclic Peptides Targeting STUB1.
Simon Ng, Alexander C Brueckner, Soheila Bahmanjah, Qiaolin Deng, Jennifer M Johnston, Corey Strickland

J Med Chem· July 2022

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Author Correction: Cryo-EM structures of inhibitory antibodies complexed with arginase 1 provide insight into mechanism of action.
Rachel L Palte, Veronica Juan, Yacob Gomez-Llorente, Marc Andre Bailly, Kalyan Chakravarthy, Corey Strickland

Commun Biol· November 2021

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Cryo-EM structures of inhibitory antibodies complexed with arginase 1 provide insight into mechanism of action.
Rachel L Palte, Veronica Juan, Yacob Gomez-Llorente, Marc Andre Bailly, Kalyan Chakravarthy, Corey Strickland

Commun Biol· July 2021

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Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation.
Chuan Hong, Noel J Byrne, Beata Zamlynny, Srivanya Tummala, Li Xiao, Corey Strickland

Nat Commun· February 2021

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Characterization and Modeling of Reversible Antibody Self-Association Provide Insights into Behavior, Prediction, and Correction.
Carl Mieczkowski, Alan Cheng, Thierry Fischmann, Mark Hsieh, Jeanne Baker, Corey Strickland

Antibodies (Basel)· February 2021

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Discovery of an Anion-Dependent Farnesyltransferase Inhibitor from a Phenotypic Screen.
Marina Bukhtiyarova, Erica M Cook, Paula J Hancock, Alan W Hruza, Anthony W Shaw, Corey Strickland

ACS Med Chem Lett· January 2021

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Crystal Structure and Characterization of Human Heavy-Chain Only Antibodies Reveals a Novel, Stable Dimeric Structure Similar to Monoclonal Antibodies.
Carl Mieczkowski, Soheila Bahmanjah, Yao Yu, Jeanne Baker, Gopalan Raghunathan, Corey Strickland

Antibodies (Basel)· November 2020

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Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis.
Giovanna Scapin, Venkata P Dandey, Zhening Zhang, Winifred Prosise, Alan Hruza, Corey Strickland

Nature· April 2018

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Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry.
Noreen F Rizvi, John A Howe, Ali Nahvi, Daniel J Klein, Thierry O Fischmann, Corey Strickland

ACS Chem Biol· March 2018

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A novel storage system for cryoEM samples.
Giovanna Scapin, Winifred W Prosise, Michael K Wismer, Corey Strickland

J Struct Biol· July 2017

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Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931)-A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer's Disease.
Jack D Scott, Sarah W Li, Andrew P J Brunskill, Xia Chen, Kathleen Cox, Corey O Strickland

J Med Chem· December 2016

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Structure-activity relationship study of 4-substituted piperidines at Leu26 moiety of novel p53-hDM2 inhibitors.
Yuan Tian, Yao Ma, Craig R Gibeau, Brian R Lahue, Gerald W Shipps, Corey Strickland

Bioorg Med Chem Lett· June 2016

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Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates.
Mihirbaran Mandal, Yusheng Wu, Jeffrey Misiaszek, Guoqing Li, Alexei Buevich, Corey Strickland

J Med Chem· April 2016

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Discovery of Novel 3,3-Disubstituted Piperidines as Orally Bioavailable, Potent, and Efficacious HDM2-p53 Inhibitors.
Stéphane L Bogen, Weidong Pan, Craig R Gibeau, Brian R Lahue, Yao Ma, Corey Strickland

ACS Med Chem Lett· March 2016

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Structure of full-length human anti-PD1 therapeutic IgG4 antibody pembrolizumab.
Giovanna Scapin, Xiaoyu Yang, Winifred W Prosise, Mark McCoy, Paul Reichert, Corey Strickland

Nat Struct Mol Biol· December 2015

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Iminopyrimidinones: a novel pharmacophore for the development of orally active renin inhibitors.
Brian A McKittrick, John P Caldwell, Thomas Bara, George Boykow, Madhu Chintala, Corey Strickland

Bioorg Med Chem Lett· April 2015

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Discovery of potent iminoheterocycle BACE1 inhibitors.
John P Caldwell, Robert D Mazzola, James Durkin, Joseph Chen, Xia Chen, Corey Strickland

Bioorg Med Chem Lett· December 2014

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