NPJ Microgravity December 2019 PMID 31815178

Pembrolizumab microgravity crystallization experimentation.

Paul Reichert, Winifred Prosise, Thierry O Fischmann, Giovanna Scapin, Chakravarthy Narasimhan, April Spinale, Ray Polniak, Xiaoyu Yang, Erika Walsh, Daya Patel, Wendy Benjamin, Johnathan Welch, Denarra Simmons, Corey Strickland

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Mentions

Peak: 2 in Dec 2019

across 3 sources since Dec 2019

Extended reach

263,758

potential audience

Total likes

1,989

Video views

250,119

Mentions per month

Dec 2019 – May 2025

Where it's discussed

X / Twitter4 posts
YouTube2 videos
News2 articles

AI synopsis

What people are saying

The discussions show a general curiosity about the new crystalline methods, evidenced by comments on improved uniformity and drug administration techniques, while also noting the technological relevance of microgravity experiments. The tone is informative but not heavily detailed, reflecting interest without deep emotional investment or critical debate.

AgreementNeither agree nor disagree

The discussions are mostly neutral or slightly positive, with some acknowledgment of the new methods but no strong consensus.

InterestModerate interest

There is some curiosity about the experimental methods and potential applications, though overall engagement remains moderate.

EngagementModerate engagement

Participants reference technical aspects like crystallization methods and implications for drug development, indicating active but not deeply detailed engagement.

ImpactModerate impact

The posts suggest that the research could influence pharmaceutical manufacturing, but the conversations do not explicitly demonstrate widespread or immediate impact.

Abstract in brief

Researchers teamed up with NASA to perform crystallization experiments on pembrolizumab (Keytruda) in the microgravity environment of the ISS, aiming to improve biologic drug manufacturing.
Microgravity conditions resulted in more uniform, high-quality crystalline suspensions with smaller, more consistent particle sizes, compared to less uniform ground-based samples.
These findings have been applied to develop new methods on Earth, such as using rotational mixers to produce uniform crystalline suspensions suitable for injectable medications, potentially enhancing drug delivery for patients.]

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All mentions

Microgravity Crystallization of Pembrolizumab for Improved Drug Manufacturing

Researchers collaborated with NASA to perform crystallization experiments on pembrolizumab in microgravity, resulting in higher quality crystals. These findings are helping develop new manufacturing methods for more…

에스오디 SOD · Mar 13, 2024 250,091 views

Advancements in Microgravity Crystallization for Biologics Manufacturing

Researchers collaborated with NASA to crystallize pembrolizumab in space, resulting in higher quality crystals. These findings improve biologic drug manufacturing and have led to new ground-based methods for producing…

แค่1นาที · May 6, 2025 29 views

starky

@astrobiopunk · X

@mogustine new methods for producing crystalline drugs with better uniformity and development of new administering techniques: https://t.co/58ivY114bg

Nov 16, 2023 · 2 likes · 494 followers View post →

Formulatrix

@formulatrix · X

NATURE: Pembrolizumab microgravity crystallization experimentation #sonicc #crystallography #crystallization https://t.co/7ubEZkWN1x https://t.co/hNsTOPNq4b

Jan 9, 2020 · 658 followers View post →

npj Journals

@Nature_NPJ · X

Pembrolizumab microgravity crystallization experimentation #npjmgrav https://t.co/bD204H64iQ https://t.co/HeeoJUQPLl

Dec 16, 2019 · 5 likes · 9,085 followers View post →

Hematopoiesis News

@Hema_News · X

Publication | Pembrolizumab #microgravity crystallization experimentation.

Dec 8, 2019 · 3,383 followers View post →

Warp drive: conducting experiments in space allows speedy results ...

News

... doi:10.1038/s41526-019-0090-3. Last updated 3 October 2024 11:38. Citation: The Pharmaceutical Journal, PJ, October 2024, Vol 313, No 7990;313(7990):: ...

Dec 18, 2025 View →

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