Publications by authors named "Cornelia Handl"

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Mosperafenib, a novel paradox breaker BRAF inhibitor with potent preclinical activity in BRAF mutated colorectal cancer.
Florian Renner, Jan Eckmann, Cornelia Handl, Jürgen Wichmann, Gabriel Schnetzler

Mol Cancer Ther· December 2025

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Author Correction: Targeting the SHOC2-RAS interaction in RAS-mutant cancers.
Zachary J Hauseman, Frédéric Stauffer, Kim S Beyer, Sandra Mollé, Elena Cavicchioli, Cornelia Handl

Nature· July 2025

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Targeting the SHOC2-RAS interaction in RAS-mutant cancers.
Zachary J Hauseman, Frédéric Stauffer, Kim S Beyer, Sandra Mollé, Elena Cavicchioli, Cornelia Handl

Nature· June 2025

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High-throughput screen of 100 000 small molecules in C9ORF72 ALS neurons identifies spliceosome modulators that mobilize G4C2 repeat RNA into nuclear export and repeat associated non-canonical translation.
Maartje J Luteijn, Varun Bhaskar, Dominic Trojer, Melanie Schürz, Hicham Mahboubi, Cornelia Handl

Nucleic Acids Res· April 2025

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Activity and Resistance of a Brain-Permeable Paradox Breaker BRAF Inhibitor in Melanoma Brain Metastasis.
Ester Bonfill-Teixidor, Raffaella Iurlaro, Cornelia Handl, Jürgen Wichmann, Alexandra Arias

Cancer Res· July 2022

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Preclinical Characterization of a Next-Generation Brain Permeable, Paradox Breaker BRAF Inhibitor.
Jürgen Wichmann, Caroline Rynn, Thomas Friess, Jeannine Petrig-Schaffland, Martin Kornacker, Cornelia Handl

Clin Cancer Res· February 2022

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A reversible haploid mouse embryonic stem cell biobank resource for functional genomics.
Ulrich Elling, Reiner A Wimmer, Andreas Leibbrandt, Thomas Burkard, Georg Michlits, Cornelia Handl

Nature· October 2017

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RNA-interacting proteins act as site-specific repressors of ADAR2-mediated RNA editing and fluctuate upon neuronal stimulation.
Aamira Tariq, Wojciech Garncarz, Cornelia Handl, Ales Balik, Oliver Pusch

Nucleic Acids Res· February 2013

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A high-throughput screen to identify enhancers of ADAR-mediated RNA-editing.
Wojciech Garncarz, Aamira Tariq, Cornelia Handl, Oliver Pusch, Michael F Jantsch

RNA Biol· February 2013

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