Publications by authors named "Corrado Spadafora"

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Reverse transcriptase inhibitors induce autophagy in a LINE-1 ORF1p-dependent manner.
Michela Damizia, Mirko Baranzini, Ilaria Sciamanna, Ludovica Altieri, Paola Rovella, Corrado Spadafora

bioRxiv· August 2025

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The epigenetic basis of evolution.
Corrado Spadafora

Prog Biophys Mol Biol· March 2023

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An Epigenetic -Based Mechanism in Cancer.
Patrizia Lavia, Ilaria Sciamanna, Corrado Spadafora

Int J Mol Sci· November 2022

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Reverse transcriptase inhibitors promote the remodelling of nuclear architecture and induce autophagy in prostate cancer cells.
Cristina Bellisai, Ilaria Sciamanna, Paola Rovella, Daniela Giovannini, Mirko Baranzini, Corrado Spadafora

Cancer Lett· May 2020

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Transgenerational epigenetic reprogramming of early embryos: a mechanistic model.
Corrado Spadafora

Environ Epigenet· January 2020

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A re-evaluation of LINE-1 ORF2 expression in LNCaP prostate cancer cells.
Erica M Briggs, Corrado Spadafora, Susan K Logan

Mob DNA· December 2019

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The active role of spermatozoa in transgenerational inheritance.
Ilaria Sciamanna, Annalucia Serafino, James A Shapiro, Corrado Spadafora

Proc Biol Sci· August 2019

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The "evolutionary field" hypothesis. Non-Mendelian transgenerational inheritance mediates diversification and evolution.
Corrado Spadafora

Prog Biophys Mol Biol· May 2018

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LINE-1-encoded reverse Transcriptase as a target in cancer therapy.
Ilaria Sciamanna, Paola Sinibaldi-Vallebona, Annalucia Serafino, Corrado Spadafora

Front Biosci (Landmark Ed)· March 2018

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Long interspersed nuclear element-1 expression and retrotransposition in prostate cancer cells.
Erica M Briggs, Susan Ha, Paolo Mita, Gregory Brittingham, Ilaria Sciamanna, Corrado Spadafora

Mob DNA· January 2018

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Sperm-Mediated Transgenerational Inheritance.
Corrado Spadafora

Front Microbiol· December 2017

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Soma to germline inheritance of extrachromosomal genetic information via a LINE-1 reverse transcriptase-based mechanism.
Corrado Spadafora

Bioessays· August 2016

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The Reverse Transcriptase Encoded by LINE-1 Retrotransposons in the Genesis, Progression, and Therapy of Cancer.
Ilaria Sciamanna, Chiara De Luca, Corrado Spadafora

Front Chem· February 2016

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Enhanced expression of LINE-1-encoded ORF2 protein in early stages of colon and prostate transformation.
Chiara De Luca, Fiorella Guadagni, Paola Sinibaldi-Vallebona, Steno Sentinelli, Michele Gallucci, Corrado Spadafora

Oncotarget· January 2016

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Soma-to-germline transmission of RNA in mice xenografted with human tumour cells: possible transport by exosomes.
Cristina Cossetti, Luana Lugini, Letizia Astrologo, Isabella Saggio, Stefano Fais, Corrado Spadafora

PLoS One· November 2015

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A LINE-1-encoded reverse transcriptase-dependent regulatory mechanism is active in embryogenesis and tumorigenesis.
Corrado Spadafora

Ann N Y Acad Sci· April 2015

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Regulatory roles of LINE-1-encoded reverse transcriptase in cancer onset and progression.
Ilaria Sciamanna, Alberto Gualtieri, Pier Francesco Piazza, Corrado Spadafora

Oncotarget· September 2014

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A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines.
Ilaria Sciamanna, Alberto Gualtieri, Cristina Cossetti, Emanuele Felice Osimo, Manuela Ferracin, Corrado Spadafora

Oncotarget· December 2013

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Increased expression and copy number amplification of LINE-1 and SINE B1 retrotransposable elements in murine mammary carcinoma progression.
Alberto Gualtieri, Federica Andreola, Ilaria Sciamanna, Paola Sinibaldi-Vallebona, Annalucia Serafino, Corrado Spadafora

Oncotarget· November 2013

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LINE-1 retrotransposon copies are amplified during murine early embryo development.
Patrizia Vitullo, Ilaria Sciamanna, Marta Baiocchi, Paola Sinibaldi-Vallebona, Corrado Spadafora

Mol Reprod Dev· February 2012

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Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors.
Gianluca Sbardella, Antonello Mai, Sara Bartolini, Sabrina Castellano, Roberto Cirilli, Corrado Spadafora

J Med Chem· August 2011

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A reverse transcriptase-dependent mechanism is essential for murine preimplantation development.
Ilaria Sciamanna, Patrizia Vitullo, Angela Curatolo, Corrado Spadafora

Genes (Basel)· May 2011

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Retrotransposon-encoded reverse transcriptase in the genesis, progression and cellular plasticity of human cancer.
Paola Sinibaldi-Vallebona, Claudia Matteucci, Corrado Spadafora

Cancers (Basel)· March 2011

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Re: In vitro evidence for a new therapeutic approach in renal cell carcinoma.
Corrado Spadafora

Int Braz J Urol· February 2010

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Retrotransposons, reverse transcriptase and the genesis of new genetic information.
Ilaria Sciamanna, Patrizia Vitullo, Angela Curatolo, Corrado Spadafora

Gene· December 2009

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