Publications by authors named "Cory A Ocasio"

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A palmitoyl transferase chemical-genetic system to map ZDHHC-specific S-acylation.
Cory A Ocasio, Marc P Baggelaar, James Sipthorp, Ana Losada de la Lastra, Manuel Tavares

Nat Biotechnol· October 2024

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Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis.
Goran Tomić, Clare Sheridan, Alice Y Refermat, Marc P Baggelaar, James Sipthorp, Cory A Ocasio

Cell Rep· May 2024

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Genotoxicity and Epigenotoxicity of Carbazole-Derived Molecules on MCF-7 Breast Cancer Cells.
Claudio Luparello, Ilenia Cruciata, Andreas C Joerger, Cory A Ocasio, Rhiannon Jones

Int J Mol Sci· March 2021

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Wheat pathogen -myristoyltransferase inhibitors: on-target antifungal activity and an unusual metabolic defense mechanism.
Roman O Fedoryshchak, Cory A Ocasio, Benjamin Strutton, Jo Mattocks, Andrew J Corran

RSC Chem Biol· June 2020

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Acylation-coupled lipophilic induction of polarisation (Acyl-cLIP): a universal assay for lipid transferase and hydrolase enzymes.
Thomas Lanyon-Hogg, Markus Ritzefeld, Lea Sefer, Jasmine K Bickel, Amalie F Rudolf, Cory A Ocasio

Chem Sci· October 2019

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Type II Kinase Inhibitors Targeting Cys-Gatekeeper Kinases Display Orthogonality with Wild Type and Ala/Gly-Gatekeeper Kinases.
Cory A Ocasio, Alexander A Warkentin, Patrick J McIntyre, Krister J Barkovich, Clare Vesely

ACS Chem Biol· October 2018

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Correction: Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety.
Supojjanee Sansook, Cory A Ocasio, Iain J Day, Graham J Tizzard, Simon J Coles

Org Biomol Chem· January 2018

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Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety.
Supojjanee Sansook, Cory A Ocasio, Iain J Day, Graham J Tizzard, Simon J Coles

Org Biomol Chem· October 2017

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A first generation inhibitor of human Greatwall kinase, enabled by structural and functional characterisation of a minimal kinase domain construct.
Cory A Ocasio, Mohan B Rajasekaran, Sarah Walker, Darren Le Grand, John Spencer

Oncotarget· November 2016

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Elaboration of tetra-orthogonally-substituted aromatic scaffolds towards novel EGFR-kinase inhibitors.
Adam J Close, Rhiannon N Jones, Cory A Ocasio, Paul Kemmitt, S Mark Roe

Org Biomol Chem· September 2016

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A crucial requirement for Hedgehog signaling in small cell lung cancer.
Kwon-Sik Park, Luciano G Martelotto, Martin Peifer, Martin L Sos, Anthony N Karnezis, Cory A Ocasio

Nat Med· October 2011

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Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade.
Joel M Hyman, Ari J Firestone, Vivi M Heine, Yun Zhao, Cory A Ocasio

Proc Natl Acad Sci U S A· August 2009

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The imidazopyridine derivative JK184 reveals dual roles for microtubules in Hedgehog signaling.
Tommaso Cupido, Paul G Rack, Ari J Firestone, Joel M Hyman, Kyuho Han, Cory A Ocasio

Angew Chem Int Ed Engl· April 2009

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Characterization of thyroid hormone receptor alpha (TRalpha)-specific analogs with varying inner- and outer-ring substituents.
Cory A Ocasio, Thomas S Scanlan

Bioorg Med Chem· January 2008

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Design and characterization of a thyroid hormone receptor alpha (TRalpha)-specific agonist.
Cory A Ocasio, Thomas S Scanlan

ACS Chem Biol· October 2006

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A high-throughput screening method to identify small molecule inhibitors of thyroid hormone receptor coactivator binding.
Leggy A Arnold, Eva Estébanez-Perpiñá, Marie Togashi, Anang Shelat, Cory A Ocasio

Sci STKE· June 2006

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Structure-based design of selective agonists for a rickets-associated mutant of the vitamin d receptor.
Steve L Swann, Joel Bergh, Mary C Farach-Carson, Cory A Ocasio, John T Koh

J Am Chem Soc· November 2002

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