Publications by authors named "Cosimo Commisso"

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The Aging Microenvironment is a Determinant of Immune Exclusion and Metastatic Fate in Pancreatic Cancer.
Priyanka Gupta, Rabi Murad, Li Ling, Yijuan Zhang, Karen Duong-Polk, Cosimo Commisso

Cancer Res· November 2025

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Organellar pH as an emerging vulnerability to exploit in cancer.
Cheska Marie Galapate, Cosimo Commisso

Trends Cancer· October 2025

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ULK1/2 Inhibitors that Degrade ATG13 Effectively Target KRAS-Mutant Cancers.
Patrick M Hagan, Huiyu Ren, Sonja N Brun, Fabiana I A Layng, Dhanya R Panickar, Cosimo Commisso

bioRxiv· October 2025

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Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancer.
Yijuan Zhang, Li Ling, Rabi Murad, Swetha Maganti, Ambroise Manceau, Cosimo Commisso

Cancer Cell· September 2025

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PI5P4Kα promotes glucose and iron acquisition to support metabolic fitness in pancreatic cancer.
Gurpreet K Arora, Ryan M Loughran, Kyanh Ly, Cheska Marie Galapate, Alicia Llorente, Cosimo Commisso

Cell Rep· September 2025

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Disabling PSGL-1 abrogates immune suppression and resistance to PD-1 blockade in pancreatic cancer.
Jennifer L Hope, Yijuan Zhang, Hannah A F Hetrick, Evelyn S Sanchez-Hernandez, Beatrice Silvestri, Cosimo Commisso

bioRxiv· May 2025

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The Aging Microenvironment as a Determinant of Immune Exclusion and Metastatic Fate in Pancreatic Cancer.
Priyanka Gupta, Rabi Murad, Lily Ling, Yijuan Zhang, Karen Duong-Polk, Cosimo Commisso

bioRxiv· May 2025

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A hormetic response model for glutamine stress in cancer.
Shea F Grenier, Cosimo Commisso

Trends Cancer· March 2025

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MICAL2 Promotes Pancreatic Cancer Growth and Metastasis.
Bharti Garg, Sohini Khan, Asimina S Courelli, Ponmathi Panneerpandian, Deepa Sheik Pran Babu, Cosimo Commisso

Cancer Res· March 2025

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Cell polarity proteins promote macropinocytosis in response to metabolic stress.
Guillem Lambies, Szu-Wei Lee, Karen Duong-Polk, Pedro Aza-Blanc, Swetha Maganti, Cosimo Commisso

Nat Commun· December 2024

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Macropinocytosis controls metabolic stress-driven CAF subtype identity in pancreatic cancer.
Yijuan Zhang, Li Ling, Swetha Maganti, Jennifer L Hope, Cheska Marie Galapate, Cosimo Commisso

bioRxiv· December 2024

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A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response.
Sandra L Leibel, Rachael N McVicar, Rabi Murad, Elizabeth M Kwong, Alex E Clark, Cosimo Commisso

Proc Natl Acad Sci U S A· July 2024

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MICAL2 Is a Super Enhancer Associated Gene that Promotes Pancreatic Cancer Growth and Metastasis.
Bharti Garg, Sohini Khan, Deepa Sheikh Babu, Evangeline Mose, Kevin Gulay, Cosimo Commisso

bioRxiv· June 2024

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Glutamine mimicry suppresses tumor progression through asparagine metabolism in pancreatic ductal adenocarcinoma.
Maria Victoria Recouvreux, Shea F Grenier, Yijuan Zhang, Edgar Esparza, Guillem Lambies, Cosimo Commisso

Nat Cancer· January 2024

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Cell polarity proteins promote macropinocytosis in response to metabolic stress.
Guillem Lambies, Szu-Wei Lee, Karen Duong-Polk, Pedro Aza-Blanc, Swetha Maganti, Cosimo Commisso

bioRxiv· January 2024

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Stopping the fat: Repurposing an antidepressant for cancer treatment.
Deepika Bhullar, Cosimo Commisso

J Exp Med· March 2023

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The lung employs an intrinsic surfactant-mediated inflammatory response for viral defense.
Sandra L Leibel, Rachael N McVicar, Rabi Murad, Elizabeth M Kwong, Alex E Clark, Cosimo Commisso

bioRxiv· January 2023

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Macropinocytosis and Cancer: From Tumor Stress to Signaling Pathways.
Guillem Lambies, Cosimo Commisso

Subcell Biochem· April 2022

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Automated Imaging and Analysis for the Quantification of Fluorescently Labeled Macropinosomes.
Koen M O Galenkamp, Cheska Marie Galapate, Yijuan Zhang, Cosimo Commisso

J Vis Exp· August 2021

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Macropinocytosis in Cancer-Associated Fibroblasts Is Dependent on CaMKK2/ARHGEF2 Signaling and Functions to Support Tumor and Stromal Cell Fitness.
Yijuan Zhang, M Victoria Recouvreux, Michael Jung, Koen M O Galenkamp, Yunbo Li, Cosimo Commisso

Cancer Discov· July 2021

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The Golgi as a "Proton Sink" in Cancer.
Koen M O Galenkamp, Cosimo Commisso

Front Cell Dev Biol· May 2021

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Metabolic regulation of EGFR effector and feedback signaling in pancreatic cancer cells requires K-Ras.
Szu-Wei Lee, Cosimo Commisso

Biochem Biophys Res Commun· December 2020

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Rac1 and EGFR cooperate to activate Pak in response to nutrient stress.
Szu-Wei Lee, Cosimo Commisso

Biochem Biophys Res Commun· December 2020

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Loss of HIF1A From Pancreatic Cancer Cells Increases Expression of PPP1R1B and Degradation of p53 to Promote Invasion and Metastasis.
Ashutosh Tiwari, Kojiro Tashiro, Ajay Dixit, Aditi Soni, Keianna Vogel, Cosimo Commisso

Gastroenterology· November 2020

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Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer.
Maria Victoria Recouvreux, Matthew R Moldenhauer, Koen M O Galenkamp, Michael Jung, Brian James, Cosimo Commisso

J Exp Med· September 2020

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