Publications by authors named "Craig A Lygate"

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Hypercontractility and Oxidative Stress Drive Creatine Kinase Dysfunction in Hypertrophic Cardiomyopathy.
Anton Xu, David Weissman, Katharina J Ermer, Edoardo Bertero, Jan M Federspiel, Craig A Lygate

Circulation· December 2025

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Nitric oxide releasing graphene for next-generation therapeutics.
Tanveer A Tabish, Craig A Lygate

Adv Drug Deliv Rev· November 2025

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Cardiac energetics in severe mitral regurgitation: relationship with eccentric hypertrophy, stroke volume, and effects of valve repair.
Mark A Peterzan, William T Clarke, Hannah A Lake, David Dearlove, John A Henry, Craig A Lygate

Eur Heart J Imaging Methods Pract· October 2025

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Hyperpolarized C and P MRS detects differences in cardiac energetics, metabolism, and function in obesity, and responses following treatment.
Andrew J M Lewis, Michael S Dodd, Joevin Sourdon, Craig A Lygate, Kieran Clarke

NMR Biomed· November 2024

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Cardiac function and energetics in mice with combined genetic augmentation of creatine and creatine kinase activity.
Sevasti Zervou, Debra J McAndrew, Hannah A Lake, Elina Kuznecova, Christopher Preece, Craig A Lygate

J Mol Cell Cardiol· November 2024

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Synthesis and characterization of amine-functionalized graphene as a nitric oxide-generating coating for vascular stents.
Tanveer A Tabish, Mian Zahid Hussain, Yangzhi Zhu, Jiabao Xu, Wei E Huang, Craig A Lygate

Appl Phys Rev· September 2024

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S-nitrosocysteamine-functionalised porous graphene oxide nanosheets as nitric oxide delivery vehicles for cardiovascular applications.
Tanveer A Tabish, Mian Zahid Hussain, Sevasti Zervou, William K Myers, Weiming Tu, Craig A Lygate

Redox Biol· June 2024

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pH-sensitive release of nitric oxide gas using peptide-graphene co-assembled hybrid nanosheets.
Tanveer A Tabish, Jiamin Xu, Christopher K Campbell, Manzar Abbas, William K Myers, Craig A Lygate

Nitric Oxide· June 2024

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Nitric Oxide Releasing Nanomaterials for Cardiovascular Applications.
Tanveer A Tabish, Mark J Crabtree, Helen E Townley, Paul G Winyard, Craig A Lygate

JACC Basic Transl Sci· May 2024

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Maintaining energy provision in the heart: the creatine kinase system in ischaemia-reperfusion injury and chronic heart failure.
Craig A Lygate

Clin Sci (Lond)· April 2024

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Mitochondria-targeted nanomedicines for cardiovascular applications.
Tanveer A Tabish, Craig A Lygate

Nanomedicine (Lond)· December 2023

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Measuring cardiomyocyte cellular characteristics in cardiac hypertrophy using diffusion-weighted MRI.
Mohsen Farzi, Sam Coveney, Maryam Afzali, Marie-Christine Zdora, Craig A Lygate

Magn Reson Med· November 2023

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Graphene nanocomposites for real-time electrochemical sensing of nitric oxide in biological systems.
Tanveer A Tabish, Yangzhi Zhu, Shubhangi Shukla, Sachin Kadian, Gurneet S Sangha, Craig A Lygate

Appl Phys Rev· November 2023

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Homoarginine and creatine deficiency do not exacerbate murine ischaemic heart failure.
Debra J McAndrew, Hannah A Lake, Sevasti Zervou, Edzard Schwedhelm, Jurgen E Schneider, Craig A Lygate

ESC Heart Fail· February 2023

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Synergistic effect on cardiac energetics by targeting the creatine kinase system: in vivo application of high-resolution P-CMRS in the mouse.
Mahon L Maguire, Debra J McAndrew, Hannah A Lake, Philip J Ostrowski, Sevasti Zervou, Craig A Lygate

J Cardiovasc Magn Reson· February 2023

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Insights Into the Metabolic Aspects of Aortic Stenosis With the Use of Magnetic Resonance Imaging.
Shveta Monga, Ladislav Valkovič, Damian Tyler, Craig A Lygate, Oliver Rider

JACC Cardiovasc Imaging· December 2022

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The Amino Acid Homoarginine Inhibits Atherogenesis by Modulating T-Cell Function.
Katrin Nitz, Michael Lacy, Mariaelvy Bianchini, Kanin Wichapong, Irem Avcilar Kücükgöze, Craig A Lygate

Circ Res· September 2022

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Influence of homoarginine on creatine accumulation and biosynthesis in the mouse.
Craig A Lygate, Hannah A Lake, Debra J McAndrew, Stefan Neubauer, Sevasti Zervou

Front Nutr· August 2022

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Assessing Myocardial Microstructure With Biophysical Models of Diffusion MRI.
Mohsen Farzi, Darryl Mcclymont, Hannah Whittington, Marie-Christine Zdora, Leah Khazin, Craig A Lygate

IEEE Trans Med Imaging· December 2021

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The Pitfalls of Cardiac Physiology in Genetically Modified Mice - Lessons Learnt the Hard Way in the Creatine Kinase System.
Craig A Lygate

Front Physiol· May 2021

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BH4 Increases nNOS Activity and Preserves Left Ventricular Function in Diabetes.
Ricardo Carnicer, Drew Duglan, Klemen Ziberna, Alice Recalde, Svetlana Reilly, Craig A Lygate

Circ Res· March 2021

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Subtle Role for Adenylate Kinase 1 in Maintaining Normal Basal Contractile Function and Metabolism in the Murine Heart.
Sevasti Zervou, Debra J McAndrew, Hannah J Whittington, Hannah A Lake, Kyung Chan Park, Craig A Lygate

Front Physiol· March 2021

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Altered calcium handling in cardiomyocytes from arginine-glycine amidinotransferase-knockout mice is rescued by creatine.
Martin Laasmaa, Jelena Branovets, Karina Barsunova, Niina Karro, Craig A Lygate

Am J Physiol Heart Circ Physiol· February 2021

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Cardiac expression and location of hexokinase changes in a mouse model of pure creatine deficiency.
Jelena Branovets, Niina Karro, Karina Barsunova, Martin Laasmaa, Craig A Lygate

Am J Physiol Heart Circ Physiol· February 2021

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Cardiac Energetics in Patients With Aortic Stenosis and Preserved Versus Reduced Ejection Fraction.
Mark A Peterzan, William T Clarke, Craig A Lygate, Hannah A Lake, Justin Y C Lau

Circulation· June 2020

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