Publications by authors named "Craig Lapsley"

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ATR, a DNA damage kinase, modulates DNA replication timing in Leishmania major.
Gabriel L A da Silva, Jeziel D Damasceno, Jennifer A Black, Craig Lapsley, Richard McCulloch

PLoS Genet· November 2025

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Leishmania major chromosomes are replicated from a single high-efficiency locus supplemented by thousands of lower efficiency initiation events.
Jeziel D Damasceno, Gabriel L A Silva, Catarina A Marques, Marija Krasilnikova, Craig Lapsley

Cell Rep· August 2025

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R-loops acted on by RNase H1 influence DNA replication timing and genome stability in Leishmania.
Jeziel D Damasceno, Emma M Briggs, Marija Krasilnikova, Catarina A Marques, Craig Lapsley

Nat Commun· February 2025

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Nanopore sequencing reveals that DNA replication compartmentalisation dictates genome stability and instability in Trypanosoma brucei.
Marija Krasiļņikova, Catarina A Marques, Emma M Briggs, Craig Lapsley, Graham Hamilton

Nat Commun· January 2025

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RAD51-mediated R-loop formation acts to repair transcription-associated DNA breaks driving antigenic variation in .
Mark John Girasol, Marija Krasilnikova, Catarina A Marques, Jeziel D Damasceno, Craig Lapsley

Proc Natl Acad Sci U S A· November 2023

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Genome duplication in relies on persistent subtelomeric DNA replication.
Jeziel Dener Damasceno, Catarina A Marques, Dario Beraldi, Kathryn Crouch, Craig Lapsley

Elife· September 2020

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Conditional knockout of RAD51-related genes in Leishmania major reveals a critical role for homologous recombination during genome replication.
Jeziel D Damasceno, João Reis-Cunha, Kathryn Crouch, Dario Beraldi, Craig Lapsley

PLoS Genet· July 2020

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Trypanosoma brucei ATR Links DNA Damage Signaling during Antigenic Variation with Regulation of RNA Polymerase I-Transcribed Surface Antigens.
Jennifer Ann Black, Kathryn Crouch, Leandro Lemgruber, Craig Lapsley, Nicholas Dickens

Cell Rep· January 2020

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Trypanosoma brucei ribonuclease H2A is an essential R-loop processing enzyme whose loss causes DNA damage during transcription initiation and antigenic variation.
Emma Briggs, Kathryn Crouch, Leandro Lemgruber, Graham Hamilton, Craig Lapsley

Nucleic Acids Res· September 2019

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Genome-wide mapping reveals conserved and diverged R-loop activities in the unusual genetic landscape of the African trypanosome genome.
Emma Briggs, Graham Hamilton, Kathryn Crouch, Craig Lapsley, Richard McCulloch

Nucleic Acids Res· December 2018

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Ribonuclease H1-targeted R-loops in surface antigen gene expression sites can direct trypanosome immune evasion.
Emma Briggs, Kathryn Crouch, Leandro Lemgruber, Craig Lapsley, Richard McCulloch

PLoS Genet· December 2018

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Mapping replication dynamics in Trypanosoma brucei reveals a link with telomere transcription and antigenic variation.
Rebecca Devlin, Catarina A Marques, Daniel Paape, Marko Prorocic, Andrea C Zurita-Leal, Craig Lapsley

Elife· May 2016

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Interactions among Trypanosoma brucei RAD51 paralogues in DNA repair and antigenic variation.
Rachel Dobson, Christopher Stockdale, Craig Lapsley, Jonathan Wilkes, Richard McCulloch

Mol Microbiol· July 2011

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How effective are maternal effects at having effects?
Andrew P Beckerman, Tim G Benton, Craig T Lapsley, Nils Koesters

Proc Biol Sci· February 2006

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Context-dependent intergenerational effects: the interaction between past and present environments and its effect on population dynamics.
Stewart J Plaistow, Craig T Lapsley, Tim G Benton

Am Nat· February 2006

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Age and size at maturity: sex, environmental variability and developmental thresholds.
Stewart J Plaistow, Craig T Lapsley, Andrew P Beckerman, Tim G Benton

Proc Biol Sci· May 2004

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Talkin' 'bout my generation: environmental variability and cohort effects.
Andrew P Beckerman, Tim G Benton, Craig T Lapsley, Nils Koesters

Am Nat· December 2003

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