Publications by authors named "Craig Rayner"

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Retraction notice to Effect of early treatment with metformin on risk of emergency care and hospitalization among patients with COVID-19: the TOGETHER randomized platform clinical trial [The Lancet Regional Health-Americas Volume 6, February 2022, 100142].
Gilmar Reis, Eduardo Augusto Dos Santos Moreira Silv, Daniela Carla Medeiros Silv, Lehana Thabane, Aline Cruz Milagres, Craig R Rayner

Lancet Reg Health Am· November 2025

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Identification of a moxidectin dose for 4- to 11-year-old children to support registration and potential use for onchocerciasis elimination: results of an open-label pharmacokinetic and safety study.
Nicholas O Opoku, Felix Doe, Mannel E Agbogah, Rukaya Laryea, Shelter K Gordor, Craig R Rayner

Parasit Vectors· July 2025

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Advancing pharmacometrics in Africa-Transition from capacity development toward job creation.
Goonaseelan Colin Pillai, Samer Mouksassi, Innocent G Asiimwe, Craig R Rayner, Steven Kern

CPT Pharmacometrics Syst Pharmacol· March 2025

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A Modern Curriculum for Training Scientists in Model-Informed Drug Development: Progress Report on FDA Grant to Train Regulatory Scientists.
Jeffrey S Barrett, Klaus Romero, Craig Rayner, Marc Gastonguay, Goonaseelan Colin Pillai

Clin Pharmacol Ther· August 2024

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The use of quantitative clinical pharmacology approaches to support moxidectin dosing recommendations in lactation.
Nolan D Wood, Danelle Smith, Sally A Kinrade, Mark T Sullivan, Craig R Rayner

PLoS Negl Trop Dis· August 2024

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Oral Fluvoxamine With Inhaled Budesonide for Treatment of Early-Onset COVID-19 : A Randomized Platform Trial.
Gilmar Reis, Eduardo Augusto Dos Santos Moreira Silva, Daniela Carla Medeiros Silva, Lehana Thabane, Vitoria Helena de Souza Campos, Craig R Rayner

Ann Intern Med· May 2023

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Early Treatment with Pegylated Interferon Lambda for Covid-19.
Gilmar Reis, Eduardo A S Moreira Silva, Daniela C Medeiros Silva, Lehana Thabane, Vitoria H S Campos, Craig R Rayner

N Engl J Med· February 2023

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Fluvoxamine for the treatment of COVID-19.
Michael G Dodds, Eileen B Doyle, Angela M Reiersen, Fran Brown, Craig R Rayner

Lancet Glob Health· March 2022

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Pharmacokinetics of oral moxidectin in individuals with Onchocerca volvulus infection.
Beesan Tan, Nicholas Opoku, Simon K Attah, Kwablah Awadzi, Annette C Kuesel, Craig Rayner

PLoS Negl Trop Dis· March 2022

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Effect of early treatment with metformin on risk of emergency care and hospitalization among patients with COVID-19: The TOGETHER randomized platform clinical trial.
Gilmar Reis, Eduardo Augusto Dos Santos Moreira Silva, Daniela Carla Medeiros Silva, Lehana Thabane, Aline Cruz Milagres, Craig R Rayner

Lancet Reg Health Am· February 2022

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Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: the TOGETHER randomised, platform clinical trial.
Gilmar Reis, Eduardo Augusto Dos Santos Moreira-Silva, Daniela Carla Medeiros Silva, Lehana Thabane, Aline Cruz Milagres, Craig R Rayner

Lancet Glob Health· January 2022

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Model-informed drug repurposing: Viral kinetic modelling to prioritize rational drug combinations for COVID-19.
Michael G Dodds, Rajesh Krishna, Antonio Goncalves, Craig R Rayner

Br J Clin Pharmacol· September 2021

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Using in silico viral kinetic models to guide therapeutic strategies during a pandemic: An example in SARS-CoV-2.
Kashyap Patel, Michael Dodds, Antonio Gonçalves, Mohamed A Kamal, Craig R Rayner

Br J Clin Pharmacol· September 2021

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Model-informed drug repurposing: A pharmacometric approach to novel pathogen preparedness, response and retrospection.
Michael Dodds, Yuan Xiong, Samer Mouksassi, Carl M Kirkpatrick, Katrina Hui, Craig R Rayner

Br J Clin Pharmacol· September 2021

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Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers.
C Glenn Begley, Mark Ashton, Jonathan Baell, Michael Bettess, Michael P Brown, Craig Rayner

Sci Transl Med· September 2021

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How COVID-19 has fundamentally changed clinical research in global health.
Jay J H Park, Robin Mogg, Gerald E Smith, Etheldreda Nakimuli-Mpungu, Fyezah Jehan, Craig R Rayner

Lancet Glob Health· May 2021

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Model-Informed Drug Development for Anti-Infectives: State of the Art and Future.
Craig R Rayner, Patrick F Smith, David Andes, Kayla Andrews, Hartmut Derendorf

Clin Pharmacol Ther· April 2021

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The Rise and Fall of Hydroxychloroquine for the Treatment and Prevention of COVID-19.
Zelyn Lee, Craig R Rayner, Jamie I Forrest, Jean B Nachega, Esha Senchaudhuri

Am J Trop Med Hyg· January 2021

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Early Treatment of COVID-19 Disease: A Missed Opportunity.
Jamie I Forrest, Craig R Rayner, Jay J H Park, Edward J Mills

Infect Dis Ther· December 2020

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The Landscape of Emerging Randomized Clinical Trial Evidence for COVID-19 Disease Stages: A Systematic Review of Global Trial Registries.
Alison Dillman, Michael J Zoratti, Jay J H Park, Grace Hsu, Louis Dron, Craig R Rayner

Infect Drug Resist· December 2020

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Correction to: Early Treatment of COVID-19 Disease: A Missed Opportunity.
Jamie I Forrest, Craig R Rayner, Jay J H Park, Edward J Mills

Infect Dis Ther· December 2020

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Accelerating Clinical Evaluation of Repurposed Combination Therapies for COVID-19.
Craig R Rayner, Louis Dron, Jay J H Park, Eric H Decloedt, Mark F Cotton

Am J Trop Med Hyg· October 2020

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Clinical trials of disease stages in COVID 19: complicated and often misinterpreted.
Jay J H Park, Eric H Decloedt, Craig R Rayner, Mark Cotton, Edward J Mills

Lancet Glob Health· October 2020

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Time to Step Up: A Call to Action For the Clinical and Quantitative Pharmacology Community to Accelerate Therapeutics for COVID-19.
Dan Hartman, Steven Kern, Fran Brown, Suzanne K Minton, Craig R Rayner

Clin Transl Sci· July 2020

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