Publications by authors named "Curt D Haffner"

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Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors.
Curt D Haffner, Adam K Charnley, Christopher J Aquino, Linda Casillas, Máire A Convery

ACS Med Chem Lett· November 2019

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2,4-Diamino-8-quinazoline carboxamides as novel, potent inhibitors of the NAD hydrolyzing enzyme CD38: Exploration of the 2-position structure-activity relationships.
David N Deaton, Curt D Haffner, Brad R Henke, Michael R Jeune, Barry G Shearer

Bioorg Med Chem· May 2018

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Genetic Ablation of CD38 Protects against Western Diet-Induced Exercise Intolerance and Metabolic Inflexibility.
Shian-Huey Chiang, W Wallace Harrington, Guizhen Luo, Naphtali O Milliken, John C Ulrich, Curt D Haffner

PLoS One· May 2016

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Discovery of 4-Amino-8-quinoline Carboxamides as Novel, Submicromolar Inhibitors of NAD-Hydrolyzing Enzyme CD38.
J David Becherer, Eric E Boros, Tiffany Y Carpenter, David J Cowan, David N Deaton, Curt D Haffner

J Med Chem· September 2015

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Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors.
Curt D Haffner, J David Becherer, Eric E Boros, Rodolfo Cadilla, Tiffany Carpenter

J Med Chem· April 2015

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N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 inhibitors. Part 1.
Curt D Haffner, Stephen A Thomson, Yu Guo, Lee T Schaller, Sharon Boggs

Bioorg Med Chem Lett· December 2010

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Substituted N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 ion channel blockers. Part 2.
Curt D Haffner, Stephen A Thomson, Yu Guo, Kimberly Petrov, Andrew Larkin

Bioorg Med Chem Lett· December 2010

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Pyrrolidinyl pyridone and pyrazinone analogues as potent inhibitors of prolyl oligopeptidase (POP).
Curt D Haffner, Caroline J Diaz, Aaron B Miller, Robert A Reid, Kevin P Madauss

Bioorg Med Chem Lett· August 2008

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2-Cyano-4-fluoro-1-thiovalylpyrrolidine analogues as potent inhibitors of DPP-IV.
Curt D Haffner, Darryl L McDougald, Steven M Reister, Brian D Thompson, Christopher Conlee

Bioorg Med Chem Lett· December 2005

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Structure-based design of potent retinoid X receptor alpha agonists.
Curt D Haffner, James M Lenhard, Aaron B Miller, Darryl L McDougald, Kate Dwornik

J Med Chem· April 2004

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Novel selective small molecule agonists for peroxisome proliferator-activated receptor delta (PPARdelta)--synthesis and biological activity.
Marcos L Sznaidman, Curt D Haffner, Patrick R Maloney, Adam Fivush, Esther Chao

Bioorg Med Chem Lett· May 2003

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